A5020924544- Child and Adolescent Psychosocial and Emotional Development
- Cognitive Abilities and Testing
- Early Childhood Education and Development
- Toxic Organic Pollutants Impact
- Indigenous Health, Education, and Rights
- Autism Spectrum Disorder Research
- Heavy Metal Exposure and Toxicity
- Mercury impact and mitigation studies
- Genetics and Neurodevelopmental Disorders
- Effects and risks of endocrine disrupting chemicals
- Bullying, Victimization, and Aggression
- Per- and polyfluoroalkyl substances research
- Reading and Literacy Development
- Language Development and Disorders
- Indigenous Studies and Ecology
- Maternal Mental Health During Pregnancy and Postpartum
- Neuroendocrine regulation and behavior
- Genomic variations and chromosomal abnormalities
- Air Quality and Health Impacts
- Motivation and Self-Concept in Sports
- Prenatal Substance Exposure Effects
- Birth, Development, and Health
- Mentoring and Academic Development
- Child Development and Digital Technology
- Attachment and Relationship Dynamics
Université Laval
2012-2022
Centre hospitalier universitaire de Québec
2012-2020
Government of Quebec
2020
Quebec Research and Development Centre
2016-2020
Research Unit on Children's Psychosocial Maladjustment
2003-2019
Centre hospitalier de l'Université Laval
2011-2019
Université de Montréal
2003
Pharmacological, genetic and expression studies implicate N-methyl-D-aspartate (NMDA) receptor hypofunction in schizophrenia (SCZ). Similarly, several lines of evidence suggest that autism spectrum disorders (ASD) could be due to an imbalance between excitatory inhibitory neurotransmission. As part a project aimed at exploring rare and/or de novo mutations neurodevelopmental disorders, we have sequenced the seven genes encoding for NMDA subunits (NMDARs) large cohort individuals affected...
Background: Prenatal exposure to methylmercury (MeHg) and polychlorinated biphenyls (PCBs) has been associated with impaired performance on attention tasks in previous studies, but the extent which these cognitive deficits translate into behavioral problems classroom deficit/hyperactivity disorder (ADHD) remains unknown. By contrast, lead (Pb) childhood ADHD disruptive behaviors several studies.Objectives: In this study we examined relation of developmental MeHg, PCBs, Pb at school age Inuit...
Home environment quality is a well‐known predictor of school readiness (SR), although the underlying processes are little known. This study tested two hypotheses: (a) child language mediates association between home characteristics (socioeconomic status and exposure to reading) SR, (b) genetic factors partly explain SR. Data were collected 6 63 months in large sample twins. Results showed that had direct effects on SR indirect through language. No correlation was found These results suggest...
The objectives were (1) to assess associations between sleep consolidation at 6, 18 and 30 months language skills 18, 30, 60 months; (2) investigate the genetic/environmental etiology of these associations. Longitudinal study a population-based twin cohort. 1029 twins from Quebec Newborn Twin Study. Sleep was derived parental reports day/night consecutive sleeping durations. Language assessed with MacArthur Communicative Development Inventory Peabody Picture Vocabulary Test months. ratio...
The etiology of autism spectrum disorder is poorly understood. Few studies have investigated the link between endocrine-disrupting chemicals and autistic traits. We examined relationship gestational phthalates traits in 3- to 4-y-old Canadian children. also potential effect modification by sex folic acid supplementation. enrolled 2,001 women>18 years age during first trimester pregnancy 2008 2011 from 10 cities Canada. At 3-4 age, 610 children underwent neuropsychological assessments...
We compared the results of different methods for diagnosing zygosity in a sample 237 same-sex pairs twins assessed at 5 and 18 months age. Despite twins' very young age early stage development, physical similarity was concordant with genotyping 91.9% cases 93.8% months, subsample 123 113 pairs, respectively. This concordance rate obtained following case-by-case assessment each pair's using shortened version Zygosity Questionnaire Young Twins (Goldsmith, 1991). Taking into account...
School readiness tests are significant predictors of early school achievement. Measuring on a large scale would be necessary for the implementation intervention programs at community level. However, assessment is costly and time consuming. This study assesses predictive value measure, Early Development Instrument (EDI), which relies kindergarten teachers' ratings children's well-being social, emotional, cognitive development. We also compared EDI with that direct test battery tests. Data...
Using a genetic design of 840 60‐month‐old twins, this study investigated the and environmental contributions to (a) individual differences in four components cognitive school readiness, (b) general ability underlying these components, (c) predictive association between readiness achievement. Results revealed that contribution shared environment for was substantial. Genetic effects were more important core abilities than each specific skill, although remained largest factor overall. Genetic,...
Little is known about why people differ in their levels of academic motivation. This study explored the etiology individual differences enjoyment and self-perceived ability for several school subjects nearly 13,000 twins aged 9-16 from 6 countries. The results showed a striking consistency across ages, subjects, cultures. Contrary to common belief, learning children's perceptions competence were no less heritable than cognitive ability. Genetic factors explained approximately 40% variance...
Abstract We report the heritability of response inhibition, latency, and variability, which are potential markers genetic risk in neuropsychiatric conditions. Genetic environmental influences on cancellation restraint, variability measured a novel variant stop signal task were studied 139 eight-year-old twin pairs from birth cohort. Cancellation (50%), restraint (27%), latency (41%) showed significant heritability, balance being non-shared and/or error. Response was not heritable, with 23%...
Lead exposure predicts altered neurodevelopment and lower intelligence quotient (IQ) in children, but few studies have examined this association children who relatively low blood lead concentrations.To test the associations between concentrations cognitive function Canadian preschoolers, with a possible moderation by sex.The data were gathered from 609 mother-child pairs Maternal-Infant Research on Environmental Chemicals (MIREC) Study. was measured umbilical maternal blood, children's...
Abstract Obsessive–compulsive disorder (OCD) is a heritable childhood-onset psychiatric that may represent the extreme of obsessive–compulsive (OC) traits are widespread in general population. We report heritability Toronto Obsessive–Compulsive Scale (TOCS), new measure designed to assess complete range OC youth. also examined dimensional nature TOCS and degree which genetic effects unique or shared between dimensions. were measured using 16,718 youth (6–18 years) at science museum....
Abstract Early disruptive behaviors, such as aggressive and hyperactive known to be influenced by genetic factors, have been found predict early school peer relation difficulties, rejection victimization. However, there is no consensus regarding the developmental processes underlying this predictive association. Genetically informative designs, twin studies, are well suited for investigating environmental etiology of The main goal present study was examine possible establishment an emerging...
About half of Nunavik Inuit live in overcrowded households compared to very few Canadians from the general population. Living is associated with greater risks suffering mental health problems for Canadian adolescents. The present work aims at studying prospectively hypothesised relationship between household overcrowding childhood and psychological distress during adolescence among Inuit, as well these phenomena when they are both measure adolescence. Recruited part Child Development Study,...
Abstract Objective: The present study aims at measuring the association between household food insecurity and psychological distress in adolescents Inuit communities, concurrently overtime from childhood to adolescence. Design: used measures of internalising behaviours (anxiety, withdrawn attitude, somatic complaints depression) as indicators during adolescence, a concurrent measure adolescence an assessment longitudinal patterns We collected descriptive information birth, on potential...
The phenotypic and genetic associations between decoding skills ADHD dimensions have been documented but less is known about the association with reading comprehension. aim of study to document comprehension inattention hyperactivity/impulsivity in early schooling compare them those skills.Data were collected two population-based samples twins (Quebec Newborn Twin Study - QNTS) singletons Longitudinal Child Development QLSCD) totaling ≈ 2300 children. Reading was assessed normed measures...
This study examined the moderating role of pragmatic language skills in relationship between perceived prosociality and gender among children two different educational contexts age groups (n = 108 childcare centres, 4–5; n 113 kindergarten, 5–6). In line with many other studies, results showed that boys were by their ECEs kindergarten teachers as being less prosocial than girls. seeking to explain this gap, played pragmatics girls was investigated tended be supported. These are discussed...