A5048665119- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Computational Drug Discovery Methods
- Biochemical and Molecular Research
- Ubiquitin and proteasome pathways
- Tannin, Tannase and Anticancer Activities
- Autophagy in Disease and Therapy
- Hippo pathway signaling and YAP/TAZ
- RNA modifications and cancer
- Advanced Computing and Algorithms
- Head and Neck Cancer Studies
- Cancer, Lipids, and Metabolism
Zhongshan Hospital
2025
Fudan University
2025
Tianjin Medical University General Hospital
2024
Tianjin Stomatological Hospital
2020
Tianjin Medical University
2020
Background: Metastatic Castration-Resistant Prostate Cancer (mCRPC) represents a critical challenge in current prostate cancer treatment. Benzimidazole Derivative XY123 has emerged as novel inhibitor for its Objective: This study aims to establish robust Quantitative Structure-Activity Relationship (QSAR) model predicting the activity of derivatives, aiding development anti-prostate drugs. Methods: Utilizing CODESSA software, descriptors were computed based on various moieties derivatives....
Objectives To investigate the effect and mechanism of anti-tumor agent hydroxycamptothecin (HCPT) on HeLa cells in cervical cancer. Materials methods Autophagy apoptosis were detected by western blotting transfection GFP-LC3 shRNA as well Hoechst staining. Results The authors found that expression regulators Beclin-1, p62, microtubule-associated protein 1 light chain 3 (LC3) upregulated then triggered occurrence cell autophagy. On other hand, HCPT could induce to formation autophagy resulted...
This paper focuses on the analysis and monitoring application of medical data for chronic diseases in elderly individuals living alone using wearable sensor wristbands. It introduces background, objectives, significance, content, methods research. The development wristbands status are discussed, highlighting existing research gaps. section characteristics needs defines term, analyzes common types diseases, examines such patients. principles technologies explained, covering working...
Objective: To explore differentially expressed genes (DEG) and pathways between human papilloma virus (HPV) positive negative head neck squamous cell carcinoma (HNSCC) to search gene targets for diagnosis treatment of HPV-related HNSCC. Methods: HNSCC expression profile chips GSE3292 (including 8 HPV-positive 28 HPV-negative tissues, which 15 collected from oral cavity cancer, 9 oropharyngeal laryngeal cancer 3 hypopharyngeal cancer) were selected Gene Expression Omnibus (GEO) database...