- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Retinal Imaging and Analysis
- Retinal and Optic Conditions
- Retinal Development and Disorders
- Ophthalmology and Eye Disorders
- Intraocular Surgery and Lenses
- Cerebrovascular and Carotid Artery Diseases
- Ocular Surface and Contact Lens
- Ophthalmology and Visual Impairment Studies
- Cerebral Venous Sinus Thrombosis
- Traumatic Ocular and Foreign Body Injuries
- Neurological Disorders and Treatments
- Facial Trauma and Fracture Management
- Visual perception and processing mechanisms
- Dermatologic Treatments and Research
- Retinal and Macular Surgery
- Carbohydrate Chemistry and Synthesis
- Educational and Social Studies
- Adaptive optics and wavefront sensing
- Spatial Cognition and Navigation
- Spaceflight effects on biology
- Corneal Surgery and Treatments
- Photoreceptor and optogenetics research
University of Turin
2012-2023
University of Pisa
2020
Allergan (Ireland)
2020
Santen (Japan)
2020
Maison des Sciences de l’Homme de Dijon
2020
S:t Eriks Ögonsjukhus
2020
Karolinska Institutet
2020
Fondazione G.B. Bietti
2020
Manchester Royal Eye Hospital
2017
Candiolo Cancer Institute
2005
Purpose. To investigate retinal function using microperimetry in patients affected by idiopathic epiretinal membrane (iERM) and cataract who underwent combined surgery: 4-year follow-up. Design. Prospective, interventional case series. Methods. 30 eyes of consecutive with iERM age-related 25-gauge vitrectomy surgery. At baseline, 90 180 days, 1 4 years, we examined mean sensitivity (MS), defect (MD), fixation stability, frequency microscotomas MP1 microperimetry. Best-corrected visual acuity...
PURPOSE: To compare phacoemulsification alone and with micro-bypass stent implantation in eyes primary open-angle glaucoma. SETTING: Instituto di Fisiopatologia Clinica, Clinica Oculistica, Universita' Torino, Italy. METHODS: In this prospective double-masked randomized clinical trial, patients had (control group) or iStent (combined group). Primary outcomes were intraocular pressure (IOP) reduction medication use over 15 months IOP after a 1-month washout of ocular hypotensive agents (ie,...
Micro-invasive glaucoma surgical implantation of trabecular micro-bypass stents, previously shown to be safe and effective for open-angle (OAG) subjects during cataract surgery, was considered evaluation as a sole procedure. The aim this study evaluate the safety intraocular pressure (IOP)-lowering efficacy after ab interno two Glaukos Trabecular Micro-Bypass iStent inject second generation devices in with OAG. This performed at sites France, Germany, Italy, Republic Armenia, Spain. In...
The purpose of this study was to compare outcomes subjects with open-angle glaucoma (OAG) not controlled on one medication who underwent either implantation two iStent inject (®) trabecular micro-bypass devices or received medical therapy consisting a fixed combination latanoprost/timolol.Of 192 qualified for the and were enrolled, 94 randomized surgery inject(®) in treated eye 98 receive therapy.At month 12 visit, 94.7% eyes (89/94) stent group reported an unmedicated intraocular pressure...
To evaluate frequency, conversion rate, and risk factors for blindness in glaucoma patients treated European Universities.This multicenter retrospective study included 2402 consecutive with at least one eye. Medical charts were inspected divided into those blind the remainder ('controls'). Blindness was defined as visual acuity≤0.05 and/or field loss to less than 10°.Unilateral bilateral respectively 11.0% 1.6% beginning, 15.5% 3.6% end of observation period (7.5±5.5 years, range:1-25...
To investigate the efficacy and safety of a cross-linked gel stent (XEN45) with or without cataract surgery in treatment glaucoma patients.Five university hospitals.Prospective multicenter clinical trial.Patients inadequately controlled by poor compliance intolerance to topical therapy were included. Patients divided into those who had an implant only (Solo Group; phakic pseudophakic patients) combined (Combo Group). Differences mean intraocular pressure (IOP) number medications between...
To assess inflammatory involvement of cornea in dry eye by means confocal microscopy, evaluating the presence and distribution Langherans cells (LCs).98 eyes 49 subjects were enrolled: 18 affected Sjögren Syndrome Dry Eye (SSDE), 17 with Non-Sjögren (NSSDE), 14 healthy volunteeers. symptoms, tear film, ocular surface damage corneal microscopy analized.A significant increase LCs density was observed at sub-basal nerve plexus (SSDE = 79 cells/mm(2) andNDE 22 cells/mm(2); p 0,0031)...
Micropulse diode laser trabeculoplasty (MDLT): A phase II clinical study with 12 months follow-up Antonio Maria Fea, Alex Bosone, Teresa Rolle, Beatrice Brogliatti, Federico GrignoloIstituto di Fisiopatologia Clinica, Clinica Oculistica dell’ Università Torino, ItalyObjective: This pilot evaluates the pressure lowering potential of subthreshold micropulse (MDLT) for a clinically meaningful duration in patients medically uncontrolled open angle glaucoma (OAG).Design: prospective...
Copy number variation (CNV) has been associated with a variety of neuropsychiatric disorders, including intellectual disability/developmental delay (ID/DD), autism spectrum disorder (ASD), and schizophrenia (SCZ). Often, individuals carrying the same pathogenic CNV display high clinical variability. By array‐CGH analysis, we identified novel familial 3q29 deletion (1.36 Mb), centromeric to region, which manifests variable expressivity. The was in 3‐year‐old girl diagnosed ID/DD segregated...
Parry-Romberg syndrome (PRS) is a rare disorder characterized by unilateral facial atrophy affecting the skin, subcutaneous tissue, muscles, and sometimes extending to osteocartilaginous structures. Ocular involvement relatively rare. We present case of 23-year-old female caucasian patient with Parry Romberg extensive ocular involvement: enophthalmos, uveitis, iris atrophy. Ultrasound biomicroscopy (UBM) demonstrated hypotrophy ciliary body. The body has been previously reported just once...
Purpose To evaluate the efficacy and safety of a new Schlemm canal scaffold microstent (Hydrus) combined with cataract surgery in routine clinical practice. Settings Clinics Italy, Poland, United Kingdom. Design Retrospective case series. Methods Clinical outcomes patients primary open-angle glaucoma who had phacoemulsification implantation were analyzed. Data (intraocular pressure [IOP], number medications, incidence complications) collected preoperatively postoperatively through 24 months....
ABSTRACT We report the comparison of field extent measured using two kinetic perimeters: 1) a double-arc perimeter developed by van Hot-van Duin for use in infants and young children, 2) standard Goldmann apparatus. Targets used were V-4-e target on both 2- 6-degree targets perimeter. Visual fields assessing looking responses toward presented pseudorandom order at 45°, 135°, 225°, 315°. Fifty-six children (mean age: 6.8 years, range: 4 to 10 years) tested, with retests undertaken In 20%. The...
Purpose. To determine the effectiveness of autologous platelet lysate (APL) eye drops in patients with primary Sjögren syndrome (SS) dry eye, refractory to standard therapy, comparison treated artificial tears. We focused on effect APL cornea morphology vivo confocal microscopy (IVCM). Methods. Patients were assigned two groups: group A used QID, and B preservative-free tears for 90 days. Ophthalmological assessments included ocular surface disease index (OSDI), best corrected visual acuity...
In Brief PURPOSE: To evaluate the correlation between white-to-white (WTW) distance as assessed by Orbscan II (Bausch & Lomb) and high-resolution magnetic resonance imaging (MRI) sulcus–sulcus (S–S) measures to analyze age anterior chamber parameters. SETTING: Istituto per la Ricerca e Cura del Cancro, Candiolo, Torino, Italy. METHODS: Eighty-eight patients had MRI with a 1.5 Tesla imager (GE Medical Systems) using 3-inch circular coil. T1 weighted fast spin-echo scans were performed on...
This study was designed to evaluate the incidence of severe ocular injuries associated maxillofacial fractures and report their management in Emergency Department.Among 1779 patients admitted for fractures, those with partial or total loss vision at time emergency consultation were included study. Data collected from patients' medical records age, gender, mechanism injury, location type facial cause blindness, methods treatment, days hospitalization.Forty (2.2%), 32 men 8 women, ranging 17...
<b><i>Purpose:</i></b> To evaluate short-term intraocular pressure (IOP) changes after phacoemulsification in glaucoma and normal patients the effect of oral acetazolamide (Diamox) to control IOP these patients. <b><i>Methods:</i></b> 120 undergoing cataract surgery were included this prospective multicenter study involving 6 University Eye Clinics: 60 with well-controlled primary open-angle (POAG) controls. Half participants received...