Transvenous embolization (TVE) for the treatment of a cavernous sinus (CS) dural arteriovenous fistula (DAVF) occasionally causes cranial nerve palsy (CNP). Overpacking coils is considered to result in CNP. The purpose this study was analyze association TVE-induced CNP with volume and location activated CS.Thirty-one patients CS DAVFs (33 lesions) underwent TVE.Cranial occurred or aggravated 13 cases (39.4%; group). cumulative significantly greater group (0.241 +/- 0.172 cm3) than non-CNP...

Glycyrrhizin has been clinically used as an anti-allergic agent, but its mechanism remains unknown. This study was undertaken to examine the effect of glycyrrhizin on thymolytic and immunosuppressive action cortisone in normal rabbits adrenalectomized rats. Immunization performed by injection bacterial a-amylase emulsified Freund's incomplete adjuvant. Antibody titer serum expressed enzyme-neutralizing activity. The circulating antibody could be detected about 10 days after immunization...

It was demonstrated by the present study that glycyrrhizin inhibited action of estradiol-17β on uterine weight and β-glucuronidase activity in ovariectomized mice rats a certain dose ratio. The inhibition 50% or more when ratio glycyrrhizin: 1000: 1. In any higher to estrogen, decreased even reversed. Glycyrrhizin itself had no effect either mice. mechanism anti-estrogenic discussed relation biological actions hepatic degradation cortisone.

The distribution and time course of expression the heat shock/stress proteins, hsp27 hsp72, were evaluated in a highly controlled gerbil model ischemic injury tolerance induction, which duration depolarization each hippocampus provides precise quantitative index insult severity. Gerbils subjected to brief priming insults (2- 3.5-minute depolarization) that produce optimal preconditioning, severe test (6- 8.5-minute complete CA1 neuron loss naive animals, or combined administered 1 week...

AbstractAbstractObjectives: The selection of therapeutic modalities, including endovascular coil embolization and surgical clipping, for management unruptured paraclinoid aneurysms, remains controversial. Detailed long-term outcome data aneurysms are still lacking. Thus, we evaluated the safety efficacy aneurysms.Methods: From January 1998 to July 2010, 138 patients underwent coiling 140 aneurysms. Their medical records radiologic images were reviewed retrospectively.Results: Complications...

This study evaluated the effectiveness of intra-aneurysmal coil embolization for large or giant carotid artery aneurysms in cavernous sinus seven patients treated by from 2001 to 2010. Only one patient showed improved neurological symptoms caused aneurysmal mass effect during mean follow-up period 53.4 ± 27.3 months. Neurological remained unchanged two patients, and deteriorated four. Intra-aneurysmal is not considered an effective treatment option sinus.

Distal filter protection allows for continuous cerebral perfusion during carotid artery stenting (CAS), although a higher risk of debris migrating into the arteries compared with other systems has been reported.To improve extent capture, we used routine aspiration blood located proximal to in internal column before retrieval device.Of 71 CAS procedures distal protection, was performed 41 procedures. The size and number particles each aspirated sample were measured under stereoscopic...

Journal Article An Inhibitory Effect of Glycyrrhizin on the Antigranulomatous Action Cortisone Get access KIRA KUMAGAI, KUMAGAI 1Third Department Internal Medicine, and Central Laboratory, Medical School Osaka University Osaka, Japan Search for other works by this author on: Oxford Academic Google Scholar SABURO YANO, YANO KAZUYUKI TAKEUCHI, TAKEUCHI KAZUHIKO NISHINO, NISHINO YOSHITSUGU ASANUMA, ASANUMA MASAHISA NANABOSHI, NANABOSHI YUICHI YAMAMURA Endocrinology, Volume 74, Issue 1, 1...

1. Glucocorticoids, cortisol and prednisolone, inhibited the ACTH effect in vitro. At concentration of about 10-5M glucocorticoid, was almost completely inhibited, but this inhibitory action not observed below 10-6M. The on glucocorticoid could be removed by a previous addition ACTH.2. Tetrahydrocortisol, methyltestosterone estradiol-17β did inhibit effect. Estradiol-17β increased production corticosterone an ACTH-free medium.3. It suggested that might based result metabolism phosphorous...

It has been previously shown in our laboratory that glycyrrhizin inhibits the antigranulomatous action of cortisone without affecting anti-inflammatory rats. In present paper, work was extended to include effect on metabolic actions liver adrenalectomized Daily injections induced a several fold increase glycogen content, tryptophan pyrrolase activity and incorporation [1-14C] acetate into cholesterol rat liver, while concomitant blocked these cortisone. Administration by itself, however, had no

Objectives: To determine whether transcranial motor-evoked potential (TCMEP) monitoring is useful for detecting blood flow insufficiency in the anterior choroidal artery (AChA) and reflects motor function during coil embolization of AChA aneurysms. Methods: We analysed MEP findings seven patients who underwent Corkscrew electrodes positioned at C3 C4 were used to deliver supra-maximal stimuli (230-550 V). TCMEPs recorded from brachioradialis, abductor pollicis brevis, tibialis, hallucis...

The authors report a rare case of huge hypervascular tentorial cavernous angioma treated with preoperative endovascular embolization, followed by successful gross-total removal. A 15-year-old girl presented scintillation, diplopia, and papilledema. Computed tomography MRI studies revealed irregularly shaped tumor located in the right occipital suboccipital regions. tumor, which had both intra- extradural components, showed marked enhancement invasion overlying bone. Angiography stain, blood...

1. Effects of various steroid hormones on cortisol metabolism were examined in vitro by the screening test, with supernatant rat liver homogenate.2. Competition was observed a reduction Δ4-3 ketone between methyltestosterone and cortisol, being greatly inhibited methyltestosterone.3. Ethinyl-estradiol metabolism, showing marked inhibition ketone.4. Progesterone delayed disappearance infused dogs.5. It is concluded that metabolic regulation constitutes an influential element homeostasis hormones.

Sturge-Weber syndrome (SWS) is a neurocutaneous disorder presenting with facial port-wine stain, along an occipital leptomeningeal angiomatosis that typically located ipsilateral to the stain. In this paper, authors present rare case of SWS associated arteriovenous malformation (AVM) instead in lobe. While patient was care authors, AVM progressively enlarged, and accompanied by progressive stenoocclusive changes venous system. The resulting brain edema finally brought about serious...

<h3>BACKGROUND AND PURPOSE:</h3> If blood flow in the ICA is reduced by use of a distal filter during CAS, stagnation proximal to occurs and this increases probability floating debris. The debris that remains after retrieval may cause cerebral embolism. However, if increased aspiration from through an catheter, could be removed while still place. purpose study was investigate changes induced aspiration. <h3>MATERIAL METHODS:</h3> A filter-protection device (AngioGuard XP) used CAS 13...

Purpose:To determine any relationship between angiographically documented flow impairment associated with the Angioguard XP cerebral protection filter during carotid artery stenting (CAS) and condition of pores in retrieved filter. Methods:To obtain baseline characteristics XP, an unused was fully expanded examined photographically from cephalad end device to structure basket. Ten assembled a hexagonal pattern made up pore group, several which were arranged 4 concentric rings surround...

Glucose-cysteine, hydroquinone, adrenaline, ascorbic acid, aspirin and butazolidin inhibit both the reduction of Δ4-3 ketone degradation side-chain in metabolism hydrocortisone vitro.PAS myleran only hydrocortisone.