A5049061791- Vitamin D Research Studies
- Vitamin C and Antioxidants Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Anesthesia and Neurotoxicity Research
- Neonatal and fetal brain pathology
- Web Data Mining and Analysis
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Stress Responses and Cortisol
- Circular RNAs in diseases
- S100 Proteins and Annexins
- Neuroinflammation and Neurodegeneration Mechanisms
- Quality and Safety in Healthcare
- Spinal Cord Injury Research
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Risk and Safety Analysis
- Pharmacological Effects and Toxicity Studies
- Occupational Health and Safety Research
Academy of Medical Sciences
2022
Affiliated Hospital of Taishan Medical University
2013-2017
China University of Geosciences
2013-2017
Hebei Medical University
2012
Diffuse brain injury (DBI) is a leading cause of mortality and disability among young individuals adults worldwide. In specific cases, DBI associated with permanent spatial learning dysfunction motor deficits due to primary secondary damage. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) major complex that produces reactive oxygen species (ROS) during the ischemic period. The aggravates damage cell death following ischemia/reperfusion injury; however, its role in remains...
Traumatic brain injury (TBI) is a worldwide phenomenon which results in significant neurological and cognitive deficits humans. Vitamin D (VD) implicated as therapeutic strategy for various diseases now. Recently, inhibition of the NADPH oxidase (NOX 2 ) was reported to protect against oxidative stress (ROS) production. However, whether alterations NOX expression activity are associated with calcitriol (active metabolite VD) treatment following TBI remains unclear. In present study, rats...
Previous studies have demonstrated that global cerebral ischemia (GCI) causes neurological deficits and neuronal cell apoptosis. Calcitriol, a biologically active metabolite of vitamin D, exerts its endocrinological influence via nuclear D receptor. It is being assessed as an emerging therapeutic strategy in models various medical conditions, including acute brain injury. The purpose the present study was to investigate neuroprotective effects calcitriol on GCI further refine potential...
The oncogenic role of circ_POLA2 has only been explored in lung cancer, whereas the which glioblastoma (GBM) is unclear. Our research involvement GBM. Circ_POLA2 and phosphatasetensinhomolog (PTEN) mRNA levels GBM paired nontumor tissues collected from 58 patients were analyzed by real-time quantitative PCR (RT-qPCR). PTEN overexpressed cells to study their interaction RT-qPCR Western blot. roles regulating cell apoptosis using assay. data revealed that was upregulated downregulated showed...
AbstractThis paper proposes a hot topic detection method based on Chinese semantic clustering. The is aimed at high-dimensional WeChat and fragmentation of information. In order to a...
The correlation analysis of the independence between behavioral influencing factors has been performed in order to find non-independent factors. Among Human Factors Analysis and Classification System (HFACS), impact high-level on bottom level is determined. This study uses empirical method, namely Structural Equation Modeling (SEM) build relationship model. After finishing framework construction safety factors, we design questionnaire survey, ultimately draw SEM model by AMOS software....
Traumatic brain injury (TBI), one of the most common diseases neurosurgery, remains high mortality and disability in population under 45 years. TBI patients suffer permanent cognitive neurological psychological disabilities. In recent years, basic clinical experiments have shown that active form vitamin D3 (vitamin D hormone, VDH) treatment can improve TBI-induced impairment mental disorders. Therefore, this paper, we focused on physiological role possible mechanism VDH supplementation...