A5110366681- Advanced biosensing and bioanalysis techniques
- Aluminum Alloys Composites Properties
- Autophagy in Disease and Therapy
- Electrochemical Analysis and Applications
- Material Properties and Applications
- Analytical Chemistry and Sensors
- Advanced ceramic materials synthesis
- Zebrafish Biomedical Research Applications
- Spine and Intervertebral Disc Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Biosensors and Analytical Detection
- Magnesium Alloys: Properties and Applications
- Berberine and alkaloids research
- Medical Imaging and Analysis
- Hernia repair and management
- Cancer therapeutics and mechanisms
- Heat shock proteins research
- Management of metastatic bone disease
- Advanced Neural Network Applications
- Testicular diseases and treatments
- Pain Management and Opioid Use
- Minimally Invasive Surgical Techniques
- Neurological Disorders and Treatments
- Aluminum Alloy Microstructure Properties
- DNA Repair Mechanisms
Shandong Academy of Sciences
2022-2025
Qilu University of Technology
2022-2025
Jiangsu University
2019-2024
Harbin University of Science and Technology
2024
King Abdullah University of Science and Technology
2024
Liaoning Provincial People's Hospital
2020-2024
Key Laboratory for High Strength Lightweight Metallic Materials of Shandong Province
2022-2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Qingdao University
2022
Affiliated Hospital of Qingdao University
2022
Revolutionary developments in analytical chemistry have led to the rapid development of self-powered photoelectrochemical (PEC) sensors. Different from conventional PEC sensors, sensors do not require an external power source or complex devices for sensitive detection targets. As a result, these enormous application potential novel portable An increasing body work is making excellent progress toward implementation detection, but there been no reviews date. The present review first introduces...
Exploiting ingenious photoelectrodes and innovative signal amplification strategies has the potential to achieve high sensitivity in self-powered cathodic photoelectrochemical (PEC) analysis. In this work, a novel PEC sensing platform was constructed by integrating synergistic of an photocathode with light-harvesting photoanode. dual photoelectrode-based system, amplified photocurrent signals were induced enhancement: (1) BiOBr improved incorporation nitrogen-doped graphene; (2) sensor...
2-Hydroxy-4-n-octyloxybenzophenone (UV-531) is a UV absorber widely used in infrastructure, cosmetics, and rubber products. The previous study found that UV-531 exposure irritate the skin interfere with androgen secretion. However, developmental toxicity neurotoxic effects of are still at an exploratory stage, on environment living organisms need to be further explored. Here, we exposed zebrafish environmental relevant doses (0.1, 0.2, 0.4, 0.8 1.6 μg/L) observed no significant toxicity, but...
Abstract Background The ability to treat glioblastoma (GBM) using the chemotherapeutic agent temozolomide (TMZ) has been hampered by development of therapeutic resistance. In this study, we assessed isoquinoline alkaloid berberine alter GBM TMZ resistance two different TMZ-resistant cell lines mimic a physiologically relevant experimental system. Methods By treating these resistant with followed TMZ, were able assess chemosensitivity cells and their parental strains, based on performance in...
Parkinson's disease (PD) is characterized by the loss of dopaminergic (DA) neurons in substantia nigra (SN) and aggregation α-synuclein (α-syn). Current PD therapies merely provide symptomatic relief, lacking disease-modifying therapeutic strategies against that could reverse ongoing neurodegeneration. In quest exploring novel modifying strategies, compounds from natural sources have gained much attention recent days. YIAEDAER (Tyr-Ile-Ala-Glu-Asp-Ala-Glu-Arg) peptide a multi-functional...
It is urgent to pursue appropriate gate photoactive materials for gate-to-channel signal modulation achieve superior transconductance performances of organic photoelectrochemical transistor (OPECT) sensors. Notably, a hole transfer layer (HTL) participant CdZnS/sulfur-doped Ti3C2 MXene (S-MXene) was designed and developed in this work, which exhibited remarkable performance by up 3 orders magnitude. Because the incorporation S-MXene with an enhanced electrical conductivity as effective HTL,...
The effects of Grp (graphite particles) addition and holding time on the microstructure mechanical properties Grp/AZ91D composite were investigated in this work. results indicated that distribution matrix was determined by self-stabilizing mechanism relationships between solidifying interface particles. Due to mechanism, a small amount would uniformly distribute melt alloy, as increased, agglomeration occur. Accordingly, former be engulfed latter pushed. With an increased time, tended...
The oncogenic role of circ_POLA2 has only been explored in lung cancer, whereas the which glioblastoma (GBM) is unclear. Our research involvement GBM. Circ_POLA2 and phosphatasetensinhomolog (PTEN) mRNA levels GBM paired nontumor tissues collected from 58 patients were analyzed by real-time quantitative PCR (RT-qPCR). PTEN overexpressed cells to study their interaction RT-qPCR Western blot. roles regulating cell apoptosis using assay. data revealed that was upregulated downregulated showed...
Summary Mammals tightly regulate their core body temperature, yet how cells sense and respond to small temperature changes at the molecular level remains incompletely understood. Here, we discover a significant enrichment of RNA G-quadruplex (rG4) motifs around splice sites cold-repressed exons. These thermosensing structures, when stabilized, mask sites, reducing exon inclusion. Focusing on cold-induced neuroprotective RBM3, demonstrate that rG4s near poison are stabilized low temperatures,...
Abstract Using an object detection network to identify power grid equipment in low-voltage stations automatically can effectively improve the accuracy and efficiency of information inspection, which is great significance safe stable operation a system. The current advanced model YOLOv8 has high tasks. However, it still suffers from leakage misclassification complex scenarios, there are higher lightweighting requirements face real-time processes. This paper proposes lightweight model,...
Resistance to temozolomide (TMZ), the frontline chemotherapeutic agent for glioblastoma (GBM), has emerged as a formidable obstacle, underscoring imperative identify alternative therapeutic strategies improve patient outcomes. In this study, we comprehensively evaluated novel agent, O6-methyl-2'-deoxyguanosine-5'-triphosphate (O6-methyl-dGTP) its anti-GBM activity both in vitro and vivo. Notably, O6-methyl-dGTP exhibited pronounced cytotoxicity against GBM cells, including those resistant...
The effects of mold temperatures on the microstructures and mechanical properties thixoforged Grp (graphite particles)/AZ91D composites have been investigated, followed by partial remelting thixoforging technology. results indicate that best semi-solid microstructure could be obtained after being partially remelted at 600 °C held for 60 min. Correspondingly, under a temperature 300 °C, tensile were thixoforging. UTS (ultimate strength) elongation Grp/AZ91D up to 304.1 MPa 13.9%,...
In the present study, we introduced a modified trocar puncturing method and evaluated its clinical application in laparoscopic high ligation of vaginal process children. A total 62 communicating hydrocele children were treated by under laparoscopy. Among them, 32 underwent with traditional (traditional group) remaining 30 (modified group). group, after 5 mm was inserted, other trocars needle pierced through skin, subcutaneous tissues, muscular layers peritoneumandwere further inserted...