A5100318547- Advanced biosensing and bioanalysis techniques
- Peroxisome Proliferator-Activated Receptors
- Cancer, Hypoxia, and Metabolism
- Advanced Photocatalysis Techniques
- RNA modifications and cancer
- Breast Cancer Treatment Studies
- Ferroptosis and cancer prognosis
- Genetic factors in colorectal cancer
- HER2/EGFR in Cancer Research
- Cancer Mechanisms and Therapy
- Biosensors and Analytical Detection
- Cancer-related molecular mechanisms research
- Immune Cell Function and Interaction
- Spinal Cord Injury Research
- Advanced Nanomaterials in Catalysis
- Cerebral Palsy and Movement Disorders
- Cancer Immunotherapy and Biomarkers
- Ovarian cancer diagnosis and treatment
- Stroke Rehabilitation and Recovery
- Circular RNAs in diseases
- Carbon and Quantum Dots Applications
- Systemic Sclerosis and Related Diseases
- Reproductive System and Pregnancy
- Metabolism, Diabetes, and Cancer
- Phagocytosis and Immune Regulation
Shandong Provincial Hospital
2024-2025
Shandong University
2024-2025
Heze University
2025
Peking University First Hospital
2015-2025
Peking University
2015-2025
University of Science and Technology of China
2020-2025
Roswell Park Comprehensive Cancer Center
2025
Hangzhou Medical College
2025
Zhejiang Provincial People's Hospital
2025
Children's Hospital of Philadelphia
2024
This work presents a heterojunction-mediated photoelectrochemical (PEC) biointerface for selective detection of microcystin-LR (MC-LR) by introducing direct Z-scheme heterojunction as efficient visible-light-driven photoactive species. Specifically, the type CdTe-Bi2S3 was designed and synthesized an ideal material, which exhibited higher PEC activity compared with either CdTe quantum dots or Bi2S3 nanorods due to improved photogenerated charges separation efficiency heterojunction. Then...
Spinal cord injury is a disabling disorder, leading to neurological impairments. Although some microRNAs have been reported be associated with spinal injury, the function of microRNA-362-3p, as one downregulated miRNAs after still unclear. In current study, models were established. Then, we performed microRNA-362-3p overexpression in rats, which expressed low microRNA-362-3p. Results from behavioral testing, hematoxylin and eosin staining Nissl revealed that over expresssion improved...
In this paper, a method of dimension reduction analysis airgap harmonics is proposed and investigated for double-rotor flux-modulated permanent magnet (DR-FMPM) motor. By analyzing the relationships among torque, core loss power factor DR-FMPM motor, characteristic related to three performances are determined, number reduced. To investigate influence on motor performances, ratios torque defined. And corresponding harmonic coefficients also Afterwards, sensitivity degrees design parameters...
Immune cells can protect against tumor progression by killing cancer cells, while aberrant expression of the immune checkpoint protein PD-L1 (programmed death ligand 1) in facilitates escape and inhibits anti-tumor immunotherapy. As a serine/threonine kinase, CK2 (casein kinase 2) regulates multiple pathways, it is still unclear effect on escape. Here found that ING4 induced autophagic degradation inhibites non-small cell lung (NSCLC) increasing T activity. However, clinical analysis...
To further heighten solar-energy utilization efficiency could be significantly meaningful for developing useful photoelectric devices. Here, by integrating the nitrogen-doped graphene-BiOBr (NG-BiOBr) nanocomposites as a photocathode with titanium dioxide (TiO2) nanoparticles photoanode synchronously, dual-photoelectrode internally driven self-powered sensing platform was fabricated, which can work without an external energy input except light illumination. In this design, microcystin-LR...
Abstract Systemic sclerosis (SSc) is a disease at the intersection of autoimmunity and fibrosis. However, epigenetic regulation contributions diverse cell types to SSc remain unclear. Here we survey, using ATAC-seq, active DNA regulatory elements eight primary cells in normal skin from healthy controls, as well clinically affected unaffected patients. We find that accessible skin-resident dendritic (DCs) exhibit highest enrichment SSc-associated single-nucleotide polymorphisms (SNPs) predict...
Background: Cellular senescence is a novel hallmark of cancer associated with patient outcomes and tumor immunotherapy. However, the value cellular senescence-related long non-coding RNAs (lncRNAs) in predicting prognosis immunotherapy response for stomach adenocarcinoma (STAD) patients needs further investigation. Methods: The transcriptome corresponding clinical information STAD genes were, respectively, downloaded from Cancer Genome Atlas (TCGA) CellAge databases. Differential expression...
Around 4% of women receive an endometrial cancer diagnosis before turning 40, mainly those without prior childbirth experience and a strong desire to preserve their ability conceive. Consequently, for young patients diagnosed with atypical hyperplasia (AEH) or early carcinoma (EC), fertility-preserving approach employing high-dose oral progesterone has been adopted. However, previous research shown notable relapse rate. Furthermore, the extended use substantial doses may hinder ovarian...
Abstract In this paper, an efficient and convenient Fe 3 O 4 /PMG/IDA-Ni 2+ nanoparticles that applied to purify immobilize his-tagged β-glucosidase was synthesized, in which, /PMG (poly ( N, N’- methylenebisacrylamide-co-glycidyl methacrylate) core/shell microspheres were synthesized firstly using distillation-precipitation polymerization, then iminodiacetic acid (IDA) used open epoxy rings on the shell of combination Ni . The gene from Coptotermes formosanus Shiraki amplified, cloned into...
// Jiaming Gao 1, 2, * , Qian Liu Ying Xu 2 Xin Gong Runyun Zhang Chenglin Zhou 3 Zhaoliang Su 4 Jianhua Jin 1 Haifeng Shi Juanjuan Yongzhong Hou Department of Oncology, The Affiliated Wujin People's Hospital, Jiangsu University, Changzhou, Province, China Institute Life Sciences, Zhenjiang, Taizhou Immunology & Laboratory Immunology, School Medicine, These authors have contributed equally to this work Correspondence to: Shi, e-mail: sjj@ujs.edu.cn Hou, houyz@ujs.edu.cn Keywords:...
The development of new catalytic materials is conducive to solving the global energy crisis and environmental problems. In this work, multipurpose catalyst unsubstituted iron(II) phthalocyanine/carbon nitride nanosheet (FePc/CN) nanocomposites were prepared by utilizing concentrated sulfuric acid as an ideal solvent CN FePc. Such FePc/CN exhibited improved photo/electrocatalytic activity which was enhanced reciprocally: photocatalytic promoted FePc anchoring, electrocatalytic doping....
Abstract TP53 mutation ( mut ) occurs in 10–20% of diffuse large B-cell lymphoma (DLBCL) cases and serves as an unfavorable biomarker DLBCL progression. It confers resistance to immunochemotherapy, high-dose chemotherapy, autologous stem cell transplantation, anti-CD19 chimeric antigen receptor T-cell therapy. Therapeutic targeting remains a significant challenge treatment. Here we assessed 667 patients with newly diagnosed DLBCL, including 576 treated immunochemotherapy rituximab,...
Abstract Background Drug resistance is an important factor affecting the efficacy of chemotherapy in patients with colon cancer. However, clinical markers for diagnosing drug tumor cells are not only a few number, but also low specificity, and mechanism action cell remains unclear. Methods Dipeptidase 1 (DPEP1) expression was analyzed using cancer genome atlas (TCGA) genotype‐Tissue Expression pan‐cancer data. Survival analysis performed survival package R software to assess prognostic value...