A5100394112- Plant-Microbe Interactions and Immunity
- Plant Pathogenic Bacteria Studies
- Plant Pathogens and Fungal Diseases
- Phytochemistry and Biological Activities
- Fungal Plant Pathogen Control
- Natural product bioactivities and synthesis
- Phytoplasmas and Hemiptera pathogens
- Mycotoxins in Agriculture and Food
- Virus-based gene therapy research
- Plant Disease Resistance and Genetics
- Genomics and Phylogenetic Studies
- Ovarian cancer diagnosis and treatment
- RNA Interference and Gene Delivery
- Biological Activity of Diterpenoids and Biflavonoids
- Plant pathogens and resistance mechanisms
- Legume Nitrogen Fixing Symbiosis
- Environmental Quality and Pollution
- Testicular diseases and treatments
- Effects and risks of endocrine disrupting chemicals
- Salmonella and Campylobacter epidemiology
- Ovarian function and disorders
- Antibiotic Resistance in Bacteria
- Customer Service Quality and Loyalty
- China's Ethnic Minorities and Relations
- Foot and Ankle Surgery
Hebei Agricultural University
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2008-2025
Peking Union Medical College Hospital
2008-2025
Northeast Agricultural University
2020-2025
City of Hope
2013-2024
Chinese Academy of Agricultural Sciences
2016-2024
South China Normal University
2024
Beckman Research Institute
2013-2024
Monash University
2024
Harbin Veterinary Research Institute
2023-2024
The Changjiang estuary and the coastal area of East China Sea (ECS) represent important interfaces terrestrial marine environments. This study included analyses water sediments collected during different seasons in these regions to determine composition microbial assemblages by means 16S rRNA gene clone libraries. We retrieved 1946 sequences 779 distinct operational taxonomic units from 36 Shannon-Weaver diversity index values rarefaction analysis indicated that bacterial sediment samples...
Clonostachys rosea is a mycoparasitic fungus that can control several important plant diseases. Here, we report on the genome sequencing of C. and comparative analysis, in order to resolve phylogenetic placement study evolution mycoparasitism as fungal lifestyle. The estimated 58.3 Mb, contains 14,268 predicted genes. A phylogenomic analysis shows clusters sister taxon pathogenic Fusarium species, with mycoparasitic/saprotrophic Trichoderma species an ancestral position. gene family reveals...
Hybrid organically bridged silica membranes have attracted considerable attention because of their high performances in a variety applications. Development robust reverse osmosis (RO) to withstand aggressive operating conditions is still major challenge. Here, new type microporous organosilica membrane has been developed and applied osmosis. Sol-gel derived RO reject isopropanol with rejection higher than 95%, demonstrating superior molecular sieving ability for neutral solutes low weight....
This study evaluated the possible prebiotic effects of dietary fucosylated chondroitin sulfate from Acaudina molpadioides (Am-CHS) on modulation gut microbiota and improvement in risk factors for chronic inflammation high fat diet-fed mice. The results showed that Am-CHS treatment greatly modified microbiota, including decrease Bacteroidetes, increase Firmicutes, elevation Lactobacillus (intestinal barrier protector) short chain fatty acid (SCFA)-producing bacteria (Lactobacillus,...
Effective maritime accident prediction will benefit both safety management and the insurance industry. Due to complex non-linearity non-stationarity nature of data, its is still a challenge in research field. An autoregressive integrated moving average with explanatory variables (ARIMAX) model was proposed predict accidents accurately, multi-factor framework developed. Additionally, impacts eight influencing factors on number were also investigated, predictions from ARIMAX contrasted those...
'Candidatus Liberibacter solanacearum' (CLso) haplotype C is associated with disease in carrots and transmitted by the carrot psyllid Trioza apicalis. To identify possible other sources vectors of this pathogen Finland, samples were taken wild plants within near fields, psyllids feeding on these plants, parsnips growing next to carrots, seeds. For analyzing genotype CLso-positive samples, a multilocus sequence typing (MLST) scheme was developed. CLso detected 11% T. anthrisci 35% Anthriscus...
Abstract Menopause is a critical window of susceptibility for its sensitivity to endocrine disrupting chemicals due the decline endogenous estrogen. Using surgical menopausal (ovariectomized) mouse model, we assessed how mammary tissue was affected by both 17β-estradiol (E2) and polybrominated diphenyl ethers (PBDEs). As flame retardants in household products, PBDEs are widely detected human serum. During physiologically-relevant exposure E2, enhanced E2-mediated regrowth glands with...
Alternaria solani is an airborne fungus and the primary causal agent of potato early blight worldwide. No available fungicides that are both effective environmentally friendly usable to control this fungus. Therefore, biological a potential approach for its suppression. In study, Bacillus subtilis strain ZD01’s fermentation broth strongly reduced A. pathogenicity under greenhouse conditions. The effects secondary metabolites on were investigated. exposure hyphae supernatant resulted in...
Previous studies have documented that 0.1≈1% of input recombinant adeno-associated virus (rAAV) vectors could be stabilized and lead to transgene expression. To characterize the steps involving massive AAV DNA loss, we designed an“AAV footprinting” strategy can track newly formed dsDNA genomes. This is based on an ROSA26R mouse model or cell line carries a lacZ gene flanked by two loxP sites. When it transduced rAAV vector carrying Cre recombinase, activated remain active even when genomes...
microRNAs (miRNAs) are implicated in plant development processes and play pivotal roles adaptation to environmental stresses. Salicornia europaea, a salt mash euhalophyte, is suitable model study mechanisms. S. europaea also vegetable, forage, oilseed that can be used for saline land reclamation biofuel precursor production on marginal lands. Despite its importance, no miRNA has been identified from thus far.Deep sequencing was performed investigate small RNA transcriptome of europaea. Two...
Haplotypes A and B of 'Candidatus Liberibacter solanacearum' (CLso) are associated with diseases solanaceous plants, especially Zebra chip disease potato, haplotypes C, D E symptoms on apiaceous plants. To date, one complete genome haplotype two high quality draft genomes have been obtained for these unculturable bacteria using metagenomics from the psyllid vector Bactericera cockerelli. Here, we present first genomic sequences carrot-associated CLso. These FIN114 (1.24 Mbp) FIN111 (1.20...
Four new compounds, including two isocoumarins, pestaloisocoumarins A and B (1, 2), one sesquiterpenoid degradation, isopolisin (4), furan derivative, pestalotiol (5), together with known isocoumarin, gamahorin (3), three chlorinated benzophenone derivatives, pestalachloride (6), E (7) a mixture of pestalalactone atropisomers (8a/8b), were isolated from culture the fungus Pestalotiopsis heterocornis associated sponge Phakellia fusca. These chemical structures established using NMR MS...
Abstract A previously unknown haplotype of the plant pathogen ‘ Candidatus Liberibacter solanacearum’ (Lso) was found in cultivated carrots and parsnips eastern Finland. That same western Finland, over 300 km away, family Polygonaceae, species Fallopia convolvulus (wild buckwheat) Persicaria lapathifolia (pale persicaria) growing as weeds within carrot parsnip fields. The infected plants, both apiaceous polygonaceous, showed symptoms foliar discolouration. This is first report Lso bacteria...
Yes-associated protein (YAP), a central effector in the Hippo pathway, is involved regulation of organ size, stem cell self-renewal, and tissue regeneration. In this study, we observed YAP activation patients with alcoholic steatosis, hepatitis, cirrhosis. Accumulation nucleus was also murine livers that were damaged after chronic-plus-single binge or moderate ethanol ingestion combined carbon tetrachloride intoxication (ethanol/CCl4). To understand role transcriptional coactivator...
Early blight, caused by the necrotrophic fungus Alternaria solani , is an important foliar disease that causes major yield losses of potato. Effector proteins secreted pathogens to host cells can inhibit immune response pathogens. Currently, function effector A . during infection poorly understood. In this study, we identified and characterized a novel candidate protein, AsCEP50. AsCEP50 protein highly expressed throughout stages Agrobacterium tumefaciens -mediated transient expression in...