A5022619179- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Medical Imaging and Pathology Studies
- Polymer crystallization and properties
- Emergency and Acute Care Studies
- Medical Imaging Techniques and Applications
- Renal and Vascular Pathologies
- Cardiac Imaging and Diagnostics
- Pediatric Urology and Nephrology Studies
- Polymer Nanocomposites and Properties
- Trauma and Emergency Care Studies
- Frailty in Older Adults
- Restraint-Related Deaths
- Chronic Disease Management Strategies
- Radiopharmaceutical Chemistry and Applications
- Orthopedic Surgery and Rehabilitation
- Health, Medicine and Society
- Hormonal Regulation and Hypertension
- Rheology and Fluid Dynamics Studies
- Healthcare Operations and Scheduling Optimization
- Skin Protection and Aging
- Urological Disorders and Treatments
- Lung Cancer Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Nanoplatforms for cancer theranostics
John Hunter Hospital
2022
Heart Foundation
2022
Health Service Executive
2020-2021
FH Foundation
2020
Oregon Health & Science University
2020
Stanford University
2012
O’Connor Hospital
2003
Joint Base San Antonio
1983-1985
Brooke Army Medical Center
1983-1985
UCSF Benioff Children's Hospital
1985
Atherosclerotic cardiovascular disease remains a major cause of death and disability, especially for high-risk familial hypercholesterolemia individuals. PCSK9i (proprotein convertase subtilisin kexin type 9 inhibitors) reduce low-density lipoprotein cholesterol levels event rates. However, prescriptions are rejected at high rates by payers, use is often delayed or eventually abandoned as treatment option. We tested the hypothesis that acute coronary syndromes, interventions, stroke, cardiac...
Background Homozygous familial hypercholesterolemia (HoFH) is a rare, treatment‐resistant disorder characterized by early‐onset atherosclerotic and aortic valvular cardiovascular disease if left untreated. Contemporary information on HoFH in the United States lacking, extent of underdiagnosis undertreatment uncertain. Methods Results Data were analyzed from 67 children adults with clinically diagnosed CASCADE (Cascade Screening for Awareness Detection) FH Registry. Genetic diagnosis was...
BackgroundCardiovascular outcomes for people with familial hypercholesterolaemia can be improved diagnosis and medical management. However, 90% of individuals remain undiagnosed in the USA. We aimed to accelerate early timely intervention more than 1·3 million at high risk heart attacks strokes by applying machine learning large health-care encounter datasets.MethodsWe trained FIND FH model using deidentified data, including procedure diagnostic codes, prescriptions, laboratory findings,...
Implementation of the 2010 Affordable Care Act (ACA) calls for a collaborative effort to transform U.S. health care system toward patient-centered and value-based care. To identify how specialty can be improved, we mapped current utilization in patients with inflammatory bowel diseases (IBD) using national insurance claims database.We performed cross-sectional study analyzing 964,633 IBD between 2012 data, including pharmacy medical claims. Frequency IBD-related (medication, tests,...
No AccessJournal of Urology1 Nov 1967Kidney Injuries in Children Thomas S. Morse, John P. Smith, William H.R. Howard, and Marc I. Rowe MorseThomas Morse More articles by this author , SmithJohn Smith HowardWilliam Howard RoweMarc View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)62929-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1967 The American Urological Association Education Research,...
This is the first report in nuclear medicine literature of scintigraphic appearance piriformis muscle syndrome. syndrome previously has been thought to be a purely clinical diagnosis and imaging modalities have ignored. However, its confusing presentation can lead unnecessary surgical exploration. case presented illustrate characteristic pattern suggest role scanning establishing diagnosis.
Cardiovascular disease (CVD), hypertension, and heart failure are associated with higher rates of coronavirus 2019 (COVID-19) related morbidity mortality [ 1 , 2 ].However, studies have documented fewer individuals presenting to hospitals acute myocardial infarction (AMI) during the pandemic 3 4 ].To better understand impact COVID-19 on AMI in pre-existing atherosclerotic cardiovascular (ASCVD), familial hypercholesterolemia (FH), or both, FH Foundation performed an analysis a large...
Background Data mining of electronic health records to identify patients suspected familial hypercholesterolemia (FH) has been limited by absence both phenotypic and genomic data in the same cohort. Methods Results Using Geisinger MyCode Community Health Initiative cohort (n=130 257), we ran 2 screening algorithms (Mayo Clinic [Mayo] flag, identify, network, deliver [FIND] FH) determine FH genetic diagnostic yields. With 29 243 excluded Mayo (for secondary causes hypercholesterolemia, no...
many patients brought to emergency departments (EDs) following an medical services (EMS) call have non-urgent needs that could be treated elsewhere. Older people are particularly vulnerable adverse events while attending the ED. Alternative care pathway models can reduce ED crowding and improve outcomes. Internationally, there is no consensus on which model recommended.the aim of this study investigate impact Pathfinder conveyance rates patient safety.the service a collaboration between...
In order to test the applicability of phenomenological theory linear viscoelasticity semicrystalline polymers, creep measurements were performed on oriented nylon 66 filaments. Stresses used 0.10, 0.35, and 0.50 g/den; temperature range was 25° 150° C; samples maintained in an anhydrous atmosphere. Under these conditions, Boltzmann's superposition principle found apply. By employing time–temperature stress relaxation data Dunell, Joanes, Rye [4], compliance at C over 26 decades time can be...
COVID-19 required rapid innovation in health systems, the context of an infection which placed healthcare professionals at high risk; general practice has been a key component that innovative response. In Ireland, GPs were asked to work network community assessment hubs. A focused training programme control procedures/clinical use personal protective equipment (PPE) was rapidly developed advance. University departments develop and deliver training. The aim this article is describe procedure...
Thirteen years of experience in the handling ileocolic intussusception a pediatric medical center were reviewed, with primary interest directed toward factors contributing to success or failure hydrostatic reduction intussusception. An increasing number patients treated primarily by barium enema, distinct improvement percentage successful reductions recent years. A detailed description method approach such patient is presented, and meticulous technique emphasized. With enthusiasm...
The authors present the first case report of a patient with lymphoma who developed disseminated cryptococcal osteomyelitis and meningitis while being treated PEP-C (prednisone, etoposide, procarbazine cyclophosphamide) chemotherapy regimen. During investigation fever new bony lesions, fungal culture from rib biopsy revealed that had osteomyelitis. Further evaluation demonstrated concurrent meningitis. patient's infections completely resolved after full course antifungal treatment....
In order to determine what correlation exists between pneumoencephalographic and clinical behavioral findings, three independent evaluations were done with 50 patients. A radiologist neurosurgeon each classified the roentgenograms according presence or absence of ventricular dilatation, abnormality cortical marking other abnormalities. pediatrician did Gesell Developmental Examinations made estimates intellectual potential neurologic status. There was no significant adaptive gross motor...
A new cholescintigraphic finding, the "hot rim" sign, is reported in a case of acute cholecystitis. Local inflammation gallbladder fossa may be cause this phenomenon.
The Placido disk is acknowledged to be one of the standard units modern ophthalmologic clinic. Every student eye soon becomes acquainted with this unique device, if not from practical use at least pages his textbook. One can safely state, however, that most clinics it for a very limited scope their activities. Certain European investigators, notably, Amsler,<sup>1</sup>of Lucerne, Hartinger,<sup>2</sup>of Jena, and Fischer,<sup>3</sup>of Leipzig, have felt need improving on ; so there are...
Introduction: Early and accurate classification of transthyretin amyloidosis (ATTR) is crucial for improving patient outcomes. However, nonspecific symptoms heterogeneous disease variations have made ATTR diagnosis challenging. Leveraging advancements in machine learning (ML) large language models (LLMs), this study aims to enhance diagnostic accuracy by analyzing electronic health records (EHRs) data. Hypothesis: Can the integration innovative feature formulation improve performance ML...
KARL, ROBERT D. Jr. M.D., LTC, MC; HARTSHORNE, MICHAEL F. MAJ, CAWTHON, A. D.O., YOUNGBLOOD, LLOYD JOYCE, ROBEY P. BUNKER, STEPHEN R. HOWARD, WILLIAM H. III MC Author Information
Abstract Flatspotting involves delayed elasticity, so conventional principles of polymer viscoelasticity should be applicable. The strain behavior the tire cord material during complex stress and thermal history is idealized in a model, assuming flatspotting caused mainly by that strains footprint area are less than cords elsewhere tread. A flatspot index based on this model empirically correlated with performance. It shown here commonly used empirical can quantitatively interpreted terms...
Thyroid tissue can be found in ectopic locations, including the retrotracheal space. This may asymptomatic or present as a cause of upper airway obstructive symptoms dysphagia (1). Seven-pinhole imaging thyroid has been suggested for routine clinical use to take advantage simultaneous anterior and oblique views, with potential subsequent tomographic reconstruction (2,3,4).