A5092351833- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebral Venous Sinus Thrombosis
- Spinal Fractures and Fixation Techniques
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Spine and Intervertebral Disc Pathology
- Substance Abuse Treatment and Outcomes
- Bone Tumor Diagnosis and Treatments
- Head and Neck Surgical Oncology
- Impact of Technology on Adolescents
- Cancer therapeutics and mechanisms
- Genetics, Aging, and Longevity in Model Organisms
- Histone Deacetylase Inhibitors Research
- Ocular Oncology and Treatments
- Management of metastatic bone disease
- Hemostasis and retained surgical items
- Alzheimer's disease research and treatments
- Medicinal Plants and Neuroprotection
- Prenatal Substance Exposure Effects
- Pituitary Gland Disorders and Treatments
- Digital Mental Health Interventions
- Cannabis and Cannabinoid Research
Northwestern University
2023-2025
Northwestern Memorial Hospital
2024-2025
Neurological Surgery
2023-2025
University of Washington
2021
BACKGROUND AND OBJECTIVES: Middle meningeal artery embolization (MMAE) for the management of chronic subdural hematoma (cSDH) has been suggested as a preferred treatment in patients where reinitiating antithrombotic (AT) therapy is necessary. In this study, we evaluate whether AT before cSDH resolution after MMAE affects radiographic and clinical resolution. METHODS: This retrospective study who underwent at our institution between 2018 2024. Clinical findings were analyzed with standard...
To the Editor: We appreciate insightful commentary by Xiaolin Du et al1 on our recent manuscript "Safety of Postembolization Antithrombotic Therapy After Middle Meningeal Artery Embolization"2 and welcome opportunity to contribute continued discussion. agree with authors' assessment that proper patient identification is important in minimizing treatment failure after middle meningeal artery embolization (MMAE). Our past research has explored association preoperative surgical risk factors...
Cranioplasty is a common surgical procedure to repair skull defects. Due cranioplasty’s relatively high complication rates, multidisciplinary teams (MSTs) of neurosurgeons and plastic surgeons have been suggested improve patient outcomes. However, indications for MST remain undefined. To investigate when MSTs are used cranioplasty report population differences outcomes compared with solo (SN), retrospective cohort study was performed at single institution. Of 355 cranioplasties, 268 (75.5%)...
Background Existing literature shows that persons with substance use disorder (SUD) experience different stages of readiness to reduce or abstain from use, and tailoring intervention change strategies these may facilitate recovery. Moreover, stigma serve as a barrier recovery by preventing SUDs seeking treatment. In recent years, the behavior technique (BCT) taxonomy has increasingly become useful for identifying potential efficacious components; however, prior not addressed extent which...
OBJECTIVE Whether obesity is associated with meningioma and the impact of by gender has been debated. The primary objective this study was to investigate differences in BMI between male female patients undergoing craniotomy for compare those other intracranial tumors. secondary location progression-free survival (PFS) obese nonobese a multi-institutional cohort. METHODS National data were obtained from Surgical Quality Improvement Program (NSQIP) database. Male analyzed separately. Patients...
OBJECTIVE A significant complication of spine surgery is persistent postoperative CSF leak secondary to intentional or incidental durotomy. Traditionally, the gold standard for repair simple durotomy has been primary surgical repair; however, this technique alone may not be possible more complex and often supplemented with sealants fibrin glues. The authors add literature largest series patients treated TachoSil, a synthetic collagen patch containing human fibrinogen thrombin, management...
INTRODUCTION: Spinal meningiomas (SMs) are histologically similar to intracranial (ICMs), but focused studies on SMs uncommon. METHODS: This is a retrospective study of patients undergoing SM resection at our institution between 2010 and 2023. Clinical radiographic characteristics were reviewed analyzed with standard statistical methods. A Partitioning Around Medoids approach was used cluster methylation data in combined cohort from publicly available dataset by profiles. also classified...
Study Design. Retrospective study. Objective. We add to the literature a series of TLIF cases using minimally invasive surgical (MIS) approach with use mechanically hinging operating table and bilateral facetectomies (Smith-Petersen osteotomy, SPO). Summary Background Data. Transforaminal lumbar interbody fusion (TLIF) cages is understood have poor preservation lordosis in can often be kyphosing procedure. Intraoperative flexion hinged increase spacing for cage placement followed by...
INTRODUCTION: Spinal meningiomas have historically been considered similar entities to intracranial meningiomas, but recent developments in molecular profiling identified unique features. METHODS: Retrospective study of patients undergoing resection spinal meningioma between 2010–2022 at our institution. Patient, radiographic, and clinical characteristics were reviewed analyzed with standard statistical methods. Molecular was conducted on three tumors. RESULTS: A total 33 tumors resected 26...
<sec> <title>BACKGROUND</title> Existing literature shows that persons with substance use disorder (SUD) experience different stages of readiness to reduce or abstain from use, and tailoring intervention change strategies these may facilitate recovery. Moreover, stigma serve as a barrier recovery by preventing SUDs seeking treatment. In recent years, the behavior technique (BCT) taxonomy has increasingly become useful for identifying potential efficacious components; however, prior not...
ABSTRACT Objective: Metastatic spinal tumors represent a rare but concerning complication of primary thyroid carcinoma. We identified demographics, metastatic features, outcomes, and treatment strategies for these in our institutional cohort. Materials Methods: retrospectively reviewed patients surgically treated metastases Demographics, tumor characteristics, modalities were collected. The functional outcomes quantified using Nurik, Modified Rankin, Karnofsky Scores. Results: Twelve who...
Acquired resistance to temozolomide (TMZ) chemotherapy due DNA mismatch repair (MMR) enzyme deficiency is a barrier improving outcomes for IDH wild-type glioblastoma (GBM) patients. KL-50 new imidazotetrazine-based therapeutic designed induce interstrand cross links, and subsequent double-stranded breaks, in an MMR-independent manner cells with O-6-Methylguanine-DNA Methyltransferase (MGMT) deficiency. Previous research showed its efficacy against LN229 glioma MMR MGMT knockdown. Its...
<h3>Introduction</h3> Middle meningeal artery (MMA) embolization is an emerging treatment for the management of chronic subdural hematomas (cSDHs) and can be performed alone or in combination with surgical evacuation. While several randomized trials are currently progress to elucidate efficacy MMA embolization, benefit this procedure appropriate patient selection criteria have not yet been definitively established. We sought review our own experience investigate differences outcomes between...
ABSTRACT This poster considers the role that information and context may play in health management. We employ a well‐known taxonomy of techniques for promoting behavioral change to consider how social media authors describe their recovery from substance use. harvest discussion posts subreddits, or forums, about alcohol, cannabis, opioids, perform content analysis identify (BCTs) described content. then use plays these BCTs, as well interventions technologies might be leveraged better support process.