A5102732449- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- Electrical and Bioimpedance Tomography
- Neurogenetic and Muscular Disorders Research
- Cerebral Palsy and Movement Disorders
- EEG and Brain-Computer Interfaces
- Stroke Rehabilitation and Recovery
- Neurological disorders and treatments
- Amyotrophic Lateral Sclerosis Research
- Pulmonary Hypertension Research and Treatments
- Solid State Laser Technologies
- Optics and Image Analysis
- Radiology practices and education
- Hemodynamic Monitoring and Therapy
- Anatomy and Medical Technology
- Genital Health and Disease
- Body Composition Measurement Techniques
- Embedded Systems and FPGA Design
- Parkinson's Disease Mechanisms and Treatments
- Vestibular and auditory disorders
- Impact of Light on Environment and Health
- Geophysical and Geoelectrical Methods
- Geophysics and Sensor Technology
- Botulinum Toxin and Related Neurological Disorders
- Assistive Technology in Communication and Mobility
Sheffield Teaching Hospitals NHS Foundation Trust
2011-2022
Royal Hallamshire Hospital
2015-2021
University of Sheffield
1992-2017
Electrical impedance myography (EIM) is a promising biomarker for amyotrophic lateral sclerosis (ALS). A key issue how best to utilise the complex high dimensional, multi-frequency data output by EIM fully characterise progression of disease.Muscle volume conduction properties were obtained from recordings tongue across three electrode configurations and 14 input frequencies (76 Hz-625 kHz). Analyses individual frequencies, averaged spectra non-negative tensor factorisation undertaken....
Objective: Gradiometers have the advantage of increasing measuring sensitivity, which is particularly useful in magnetic induction spectroscopy (MIS) for bio-impedance measurements. Traditional gradiometers use a pair field sensing coils equally distant and on opposite sides drive coil, provides high immunity to interference. In this paper, ferrite-cored coaxial gradiometer probe 29 mm diameter has been developed impedance spectra cervical tissues vivo. Approach: It consists ferrite rod with...
Objective.Electrical impedance myography (EIM) shows promise as an effective biomarker in amyotrophic lateral sclerosis (ALS). EIM applies multiple input frequencies to characterise muscle properties, often via electrode configurations. Herein, we assess if non-negative tensor factorisation (NTF) can provide a framework for identifying clinically relevant features within high dimensional dataset.Approach.EIM data were recorded from the tongue of healthy and ALS diseased individuals....
Electrical impedance myography (EIM) performed on the centre of tongue shows promise in detecting amyotrophic lateral sclerosis (ALS). Lateral recordings may improve diagnostic performance and provide pathophysiological insights through assessment asymmetry. However, it is not known if electrode proximity to muscle edge, or rotation, distort spectra. We evaluated this using finite element-based modelling.Nine thousand EIM from patients healthy volunteers were used develop a element model for...
Functional electrical stimulation has been shown to be a safe and effective means of correcting drop foot central neurological origin. However, despite recent technological advances, the set-up surface stimulators remains challenge for many users with foot. The automation setup process through use electrode arrays proposed as way address this problem. This paper describes series research clinical studies which have led first demonstration unsupervised automated an electrode-array based...
Abstract We developed a 64 channel sensory electrical stimulator which delivers dynamic and variable ‘Sensory Barrage’ Stimulation (SBS). Our aim was to assess the feasibility of caregivers delivering stimulation in community for clinical trial comparing single Transcutaneous Electrical Nerve (TENS) with SBS post stroke upper limb spasticity. trained 16 participants spasticity sequentially administer TENS 60 min daily four weeks each, washout period two between. Outcome measures tested were...
This paper provides an overview of the usability engineering process and relevant standards informing development medical devices, together with adaptations to accommodate situations such as global pandemics where use traditional face-to-face methods is restricted. To highlight some those adaptations, a case study project developing novel electronic rehabilitation device referenced, which commenced in November 2020 amidst COVID-19 pandemic. The Sheffield Adaptive Patterned Electrical...
The technique of impedance tomography using magnetically induced currents is shown to be capable reconstructing two dimensional images from a three phantom.
A mismatch in electrode impedance is a common and significant source of artefact electrical spectroscopy systems.We have analysed these artefacts, identifying key parameters the optimisation both current voltage excited used this information to develop new clinical system for investigating muscle anisotropy human limbs, with aim developing biomarkers various pathologies.This instrumentation integrates buffering at front-end, which isolates electrodes from multiplexing wiring...
Results of high-speed photographic studies mode patterns and output polarization ruby lasers using the STL image-converter camera are discussed. High optical quality rods produce complex in every spike they may change within a spike. These always located center rod. A similar study rod with c axis at 1.8° to shows that it does emit preferential polarization.
A narrow band near-UV backlight source with application in a new type of liquid crystal display is described. The light pulse driven, mercury-argon gas, low-pressure discharge lamp. Pulse driving and lamp filling conditions are described for which the ratio radiant outputs at 365 254 nm enhanced considerably compared same when it operated conventional ac ballast. Pulsed operation shown also to increase absolute output group transitions near respective power from total input power.
The difficulties of showing fine detail in a tiny area radiograph to large audience have always been recognised. Agfa-Gevaert copying stand does not deal with originals less than 12.5 × 10 cm, without the addition locally made additional masking frame and new lens or attachment.
Background Radiofrequency (RF) devices are widely used in arthroscopic shoulder surgery for tissue ablation and other effects. They have heating effect during application. It is known that chondrocyte death occurs with temperatures above 45 °C. The present study aimed to investigate the of various factors on RF probes a controlled vitro model. Methods A perspex model was used, which volume, flow, outflow position, duration probe use inflow temperature could be closely controlled. Results...
When Astra Pharmaceuticals withdrew Umbradil Viscous from the market two or three years ago this product was sorely missed, for it only medium on that contained a local anaesthetic. Arrangements were made with our hospital pharmacy department to produce combining features of adequate opacity X rays, anaesthetic content and an viscosity.