A5022463458- BIM and Construction Integration
- Preterm Birth and Chorioamnionitis
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Reproductive tract infections research
- Reproductive System and Pregnancy
- Construction Project Management and Performance
- Prenatal Screening and Diagnostics
- Global Maternal and Child Health
- Multi-Agent Systems and Negotiation
- Neonatal and fetal brain pathology
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Business Process Modeling and Analysis
- Pregnancy-related medical research
- Semantic Web and Ontologies
- Infant Development and Preterm Care
- Manufacturing Process and Optimization
- Pelvic floor disorders treatments
- Advanced Manufacturing and Logistics Optimization
- Service-Oriented Architecture and Web Services
- Grief, Bereavement, and Mental Health
- Collaboration in agile enterprises
University of Sheffield
2016-2025
Sheffield Teaching Hospitals NHS Foundation Trust
2005-2024
Southmead Hospital
2023
University of North Sumatra
2023
North Bristol NHS Trust
2023
Jessop Hospital
2012-2022
Royal College of Obstetricians and Gynaecologists
2022
Royal College of Midwives
2022
University of Florida
2017-2022
King's College London
2013-2018
Background— Hypertensive disorders of pregnancy are a major contributor to death and disability for pregnant women their infants. The diagnosis preeclampsia by using blood pressure proteinuria is limited use because they tertiary, downstream features the disease. Placental growth factor (PlGF) an angiogenic factor, secondary marker associated placental dysfunction in preeclampsia, with known low plasma concentrations Methods Results— In prospective multicenter study, we studied diagnostic...
Abstract Global response to COVID-19 pandemic has inadvertently undermined the achievement of existing public health priorities and laregely overlooked local context. Recent evidence suggests that this will cause additional maternal childhood mortality morbidity especially in low- middle-income countries (LMICs). Here we have explored contextual factors influencing maternal, neonatal children (MNCH) care Bangladesh, Nigeria South Africa amidst pandemic. Our findings suggest between March May...
Rapid innate immune defences against infection involve the recognition of invading pathogens by specific pattern receptors recently attributed to family Toll-like (TLR). Little is known about in vivo protein expression or distribution TLR female reproductive tract humans. It likely that reflects immunological tolerance commensal organisms lower parts (vagina, ectocervix and, partially, endocervix) and intolerance microbial flora upper (the uterus uterine tubes).Using immunohistochemistry...
Purpose The paper seeks to focus on the role of knowledge management in promoting corporate sustainability construction industry context. It proposes a maturity roadmap – STEPS facilitate implementation strategy. Design/methodology/approach Two research methods were used. first consisted postal questionnaire sent top 170 UK firms consisting engineering design and contractor firms. organisations selected because they considered most influential sector. second method involved 28 case study...
Delayed access to antenatal care ('late booking') has been linked increased maternal and fetal mortality morbidity. The aim of this qualitative study was understand why some women are late care.27 presenting after 19 completed weeks gestation for their first hospital booking appointment were interviewed, using a semi-structured format, in community maternity settings South Yorkshire, United Kingdom. Interviews transcribed verbatim entered onto NVivo 8 software. An interdisciplinary,...
A major challenge in preventing preterm birth (PTB) is identifying women at greatest risk. This pilot study prospectively examined the differences vaginal microbiota and metabolite profiles of who delivered prematurely compared to their term counterparts a cohort asymptomatic (studied 20-22, n = 80; 26-28 weeks, 41) symptomatic 24-36 37). Using 16S rRNA sequencing, from cervicovaginal fluid samples was characterised into five Community State Types (CST) dominated by Lactobacillus spp.: CSTI...
Objective We reviewed the prenatal and postnatal management of fetal lower urinary tract obstruction (LUTO) in a large geographically defined population. Methods The records 113 cases LUTO seen over 14-year period were examined. predictive accuracy findings for chronic renal failure (CRF) comparison prenatal-suspected non-suspected made. Results incidence was 2.2 10 000 births. During study period, detection improved from 33 to 62%. Sensitivity ultrasound dysplasia sodium, calcium,...
To determine the cost to NHS resulting from multiple pregnancies arising IVF treatment in UK, and compare those costs with due singleton treatment.A modelling study using data published literature national sources public domain, calculating direct diagnosis of a clinical pregnancy until end first year after birth.Academic Unit Reproductive Developmental Medicine.Theoretic core literature.The analysis was based on total annual number births an UK. Main outcome measures per singleton, twin or...
Abstract Objectives To describe three cases of placental mesenchymal dysplasia (PMD) associated with abnormal karyotype and review the reported in literature. Methods The were retrieved from files different institutions. A search English language literature was performed using Medline database. Results Placental abnormalities suggestive molar changes seen on prenatal ultrasound scans. Histologically, had large, hydropic stem villi myxomatous stroma, cistern formation ‘chorangiomatoid’...
This paper describes a new approach to the improved processing of clients' requirements in construction. It is designed address deficiencies current briefing practices, as well satisfy for concurrent life-cycle design and based on client model (CRPM), which uses quality function deployment, methodology used manufacturing encapsulate "voice customer" product development, other techniques, its functional mechanism. A brief review need practices that have necessitated development this followed...
Purpose The twenty‐first century is now seen as the time for construction industry to embrace new ways of working if it continue be competitive and meet needs its ever demanding clients. Collaborative considered by many essential design teams are consider whole lifecycle process. Much recent work undertaken on collaborative has focused delivery technological solutions with a focus web (extranets), CAD (visualisation), knowledge management technologies. However, recognised that good...
Purpose The advent of web services and the semantic have opened up opportunities for a new generation interoperable systems on web. purpose this paper is to show importance semantics in design construction, how has long been recognised addressed varying extents by researchers. Design/methodology/approach There now potential designs be developed through system collaborating input construction team members. also extends phase where designers can provide more timely responses problems...
Background:Concentrations of the anti-angiogenic factor soluble fms-like tyrosine kinase-1 (sFlt-1) are altered in peripartum cardiomyopathy (PPCM). In this study we investigated changes angiogenesis balance PPCM.
The Industry 4.0 wave has driven various industries to be increasingly digital. Under this trend, the construction industry is also seeking out new ways keep pace with rapid transformation. As one of major technologies associated Industrial 4.0, digital twins (DT)—a subset cyber-physical systems (CPS)—shows enormous potential benefit industry. aim paper present a comprehensive, up-to-date literature review and critical analysis existing research into DT applications, view identifying...
Within this document we use the terms pregnant woman and women's health. However, it is important to acknowledge that not only people who identify as women for whom necessary access care. Obstetric gynaecology services delivery of care must therefore be appropriate, inclusive sensitive needs those individuals whose gender identity does align with sex they were assigned at birth.