A5102845116- Palliative Care and End-of-Life Issues
- Health, Nursing, Elderly Care
- Religion, Spirituality, and Psychology
- Patient Dignity and Privacy
- Corneal Surgery and Treatments
- Ethics in medical practice
- Nuts composition and effects
- Palliative and Oncologic Care
- Muscle metabolism and nutrition
- Lymphoma Diagnosis and Treatment
- MicroRNA in disease regulation
- S100 Proteins and Annexins
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Healthcare during COVID-19 Pandemic
- Resilience and Mental Health
- Health Education and Validation
- Renin-Angiotensin System Studies
- Ocular Surface and Contact Lens
- Lysosomal Storage Disorders Research
- Education and Learning Interventions
- Sphingolipid Metabolism and Signaling
- Parkinson's Disease and Spinal Disorders
- COVID-19 Prevention and Impact
- Genomic variations and chromosomal abnormalities
Faculdade Ceres
2015-2023
Faculdade de Medicina de São José do Rio Preto
2003-2022
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2021
Ceres
2020
Hospital de Base
2008
Universidade Federal de São Paulo
2004
Hospital de Base
2001
Background/Objectives: Palliative Care is a key component to health care. In Brazil, the population has limited access Care, and it remains little-known subject. Last Aid Courses (LAC) for adults have been established since 2015 in 22 countries Europe, Australia, America Asia improve public discussion about death dying empower people participate end-of-life care provision. Brazil LAC started 2020. The aim of present study was investigate if LACs contribute bringing knowledge awareness...
To determine the efficacy of tranilast as an adjunctive therapy in conjunctival autograft.Twenty-nine patients were randomly allocated to Tranilast Group (n=15) or Control (n=14). The received a subconjunctival injection 0.5% 30 days prior surgery. Conjunctival autograft was performed both groups using fibrin sealant and 0.02% mitomycin C at end After resection pterygium, immunohistochemistry with 100 cells identify epithelial positive for transforming growth factor-β (TGF-β). Subjective...
Small non-coding regulatory RNAs control cellular functions at the transcriptional and post-transcriptional levels. Oral squamous cell carcinoma is among leading cancers in world presence of cervical lymph node metastases currently its strongest prognostic factor. In this work we aimed finding small expressed oral that could be associated with metastasis.
In oral squamous cell carcinoma (OSCC), the HIF-1 complex promotes expression of genes involved in specific mechanisms survival under hypoxic conditions, such as plasminogen activator inhibitor-1 (PAI-1), carbonic anhydrase 9 (CAIX), and vascular endothelial growth factor A (VEGFA). The study aimed to investigate presence prognostic value PAI-1, CAIX, VEGFA OSCC.Immunohistochemistry was used analyze expressions these proteins 52 tumoral tissue samples patients with OSCC, surgically treated...
Palliative care (PC) is a relatively new field in Brazil, but this knowledge of great importance medical practice.To evaluate the degree confidence among students and first-year second-year internal medicine residents addressing issues death terminal illness with patients their families.A modified version Self-Efficacy Care Scale was applied to 293 first year sixth at School Medicine São José do Rio Preto 43 or second practice same institution 2015. The questionnaire evaluated students'...
Summary Background There is renewed interest in the role played by specific counter‐regulatory mechanisms to control inflammatory host response, poorly investigated human pathology. Here, we monitored expression of two anti‐inflammatory mediators, annexin 1 and galectin‐1, assessed their potential link glucocorticoids' (GCs) effective nasal polyposis (NP). Methods Total patterns mRNA protein were analysed quantitative real‐time PCR (qPCR) Western blotting analyses, whereas ultrastructural...
Ischemia-reperfusion (IR) injury results from inflammation and oxidative stress, among other factors. Because of its anti-inflammatory antioxidant properties, the Brazil nut (BN) might attenuate IR renal injury.The aim present study was to investigate whether intake BN prevents or reduces kidney inflammation, improving function decreasing stress.Male Wistar rats were distributed into six groups (N=6/group): SHAM (control), treated with 75 150 mg BN, IR, BN. The procedure consisted right...
INTRODUÇÃO: A importância das autópsias é um tema comum de discussão tanto no Brasil como em todo o mundo, já que pode elucidar as causas óbito e tem valor social muito amplo. Entretanto, esta prática vem sendo gradualmente considerada desnecessária, tendo ocorrido declínio número exames post-mortem. OBJETIVOS: Comparar diagnóstico clínico patológico pacientes com difícil pre-mortem. MÉTODOS: Foram analisados todos os casos (em total 98) oriundos três unidades terapia intensiva...
Chronic inflammation during morbid obesity significantly alters cutaneous tissue. Large weight loss achieved after bariatric surgery minimizes or halts damage caused by metabolic syndrome, but further deteriorates the clinical condition of skin. Postbariatric skin flaccidity produces major difficulties to plastic surgery. In this study, we analyzed differences in protein composition between patients with and those large established correlations differentially expressed proteins...
PURPOSE: To evaluate the effectiveness of mitomycin C (MMC) in preventing recurrence pterygium following conjunctival autograft transplantation (CAT). Ki-67 antigen to epithelial cell proliferation and fibroblast nuclear kariometry were used assist treatment evaluation. METHODS: Twenty-nine patients with recurrent divided into three groups: Group (G) 1 - CAT placebo eyedrops (PED); G2 CAT, 0.015% MMC subconjunctivally, PED; G3 0.02% eyedrops. Immunohistochemistry for nuclei performed on...
Lymph node metastasis is one of the most important prognostic factors in head and neck squamous cell carcinomas (HNSCCs) critical for delineating their treatment. However, clinical histological criteria diagnosis nodal status remain limited. In present study, we aimed to characterize proteomic profile lymph from HNSCC patients. used one- two-dimensional electrophoresis mass spectrometry analysis HNSCC. Comparison metastatic non-metastatic nodes showed 52 differentially expressed proteins...
Autonomous and critical reflection on decision-making processes is also the object of construction in higher education.Such capacity essential for professional ethical action can be operationalized as "moral competence", referring to ability make judgments based principles, even adverse situations which subject does not find support their opinions.This evaluation simulates complex conflicting dilemmatic situations, frequent practice, especially those dealing with human lives social...
O desenvolvimento de competências e habilidades necessárias para o processo pesquisa científica na graduação em medicina deve ser parte integrante do currículo uma escola médica preocupada com a formação profissionais relevantes sociedade. Integrar saúde é um desafio que exige mudança cultura institucional. É necessário haver espaços específicos matriz curricular atividades produção divulgação científica, comunidade acadêmica seja motivada participar desse processo. Descrever reestruturação...
Objective: To evaluate which risk factors contribute directly or indirectly to Toxoplasma gondii infection in patients with ocular toxoplasmosis. 
 Methods: Between 2018-2020, a total of 306 were selected, and treated at the Retinology Outpatient Clinic Specialty Hospital Sāo José do Rio Preto, state São Paulo. After fundoscopy test, Enzyme Linked Fluorescent Assay (ELFA) was used determine IgG IgM class anti-Toxoplasma antibodies. Results: The results showed that individuals aged 60...
INTRODUÇÃO: As normas e leis da sociedade, até recentemente, permitiam ou não puniam a violência de gênero, como nos casos assassinatos mulheres em que se alegava defesa honra. Assim, últimos anos, várias medidas foram tomadas com o intuito prevenir combater problema. OBJETIVO: Descrever as novas abordagens médicas vítimas doméstica na atenção primária. MÉTODO: A coleta dos dados deu por meio um questionário confeccionado estudantes medicina, após consulta pela telemedicina, quando...
The popularity of Morinda Citrifolia Linn (Noni) as a dietary supplement, food functional ingredient, or natural health enhancer is increasing throughout the world.Our study aims to investigate concentrations 10% and 50% Citifolia usage time its renal hepatic toxicity.To this purpose, 42 male wistar rats were distributed into groups: treated for 15 days with concentration 50and 90 50%.Noni juice has been prepared fruit's pulp seeds at diluted in water.The groups presented elevated...
To explore the effectiveness and possible toxicity of use epidermal growth factor receptor inhibitor (EGFR Inhibitor), Celecoxib (COX2 inhibitor) Sirolimus (m-TOR as single agents drug combinations for treatment lung cancer in an experimental model. Lung was induced Balb-C mice by intraperitoneal injection urethane. Mice were treated with water (control) , Erlotinib (E) (50 mg/kg), (X) (R) (2 mg/kg) given alone following doublet triplet same dosages 7 days. The number pulmonary nodules...
A apoptose, como evento celular, tem uma participacao importante na tumorigenese, determinando o crescimento tumoral e sua agressividade. O presente estudo, teve objetivo, examinar a relacao entre diagnostico histopatologico prognostico neoplasia mamaria canina. Trinta cadelas foram submetidas exerese fragmento submetido ao metodo de marcacao das celulas apoptoticas, que marca fragmentos DNA da celula em conhecido desoxinucleotideo terminal transferase (TdT) mediado pela 5' desoxiuridina...

 The new coronavirus (SARS-CoV-2), whose disease is COVID-19, in March 2020, spread around the world. To minimize deleterious effects of emotional vulnerability, many strategies are use worldwide, such as support groups, online courses, social networks, web meetings, yoga practice, meditation, and other contemplative religious spiritual activities. Religious beliefs have been used to deal with tough situations and, through scientific literature still not so clear about role...
Renal injury induced by rheumatoid arthritis is not clear and may be related to the angiotensin II. We aim investigate adjuvant-induced (AIA) in rat kidney, focusing II/AT