Successful single-cell isolation is a primary step for subsequent chemical and biological analyses of single cells. Conventional methods often encounter operational complexity, limited efficiency, deterioration cell viability, incompetence in the into nanoliter liquid, and/or inability to select adherent cells with specific phenotypes. Here, we develop hand-held pipet (hSCP) that rapid, operationally simple, highly efficient, inexpensive unbiased viable suspended directly from submicroliter...

Abstract Downhole drilling operations expose all-metal positive displacement motors (AMPDM) to abrasives of different sizes, causing serious abrasive wear behavior. Controlling the entry large particles into motor by installing a filter can effectively reduce conditions and improve its lifespan. This study investigated particle size effect on seek an appropriate for AMPDM. The multi-function tribo-tester was modified according actual working stator rotor. tribological properties material...

How motile microorganisms or self-propelled synthetic swimmers interact with a curved surface is crucial in determining their locomotion patterns complex geometry. We used micrsoswimmer model (i.e., the squirmer) and performed two-dimensional study on hydrodynamic interaction between microswimmers circular obstacle. revealed that both pullers pushers, i.e., two types of squirmers, may exhibit flower-like paths as they are circling around obstacle at nonzero Reynolds numbers. Flowers various...

In order to study the temperature distribution in a multi-functional oven and optimize structural parameters of oven, internal uniformity was improved. The test conducted numerical simulation two ways. field each layer ovens measured real time using 13-point distributed thermocouple, index analyzed. inside numerically simulated computational fluid dynamics. Investigated heat conduction, convection radiation effects respectively, found out main transfer mode oven. Further through measurement,...

We apply an asymptotic analysis to a nonlinear magnetohydrodynamic boundary-layer flow over stretching sheet with two types of boundary conditions: slip and no-slip. The original partial differential equations governing the regime are first transformed into ordinary equation by using special type similarity transformation. Asymptotic solutions then obtained in simple explicit form via homotopy renormalization method. These satisfy conditions, and, for values parameters, just exact solutions....

The super-efficient sample mixing induced by the induced-charge electrokinetic flow around conducting/Janus cylinder was numerically studied in a confined |U-shaped microchannel with suddenly applied DC weak electric filed. It?s found that there are four large circulations conducting and two smaller Janus cylinder. results show samples can still be well mixed high flux due to electroosmosis. It is demonstrated local provide effective means enhance between different solutions. dependence of...

Increased speed is not only the goal of human sports but also aim we seek to achieve for artificial microswimmers. Microswimmers driven by various power mechanisms have shown unrivaled advantages in drug delivery and cancer therapy. Attaining high mobility with limited has been a never-ending motive researchers. We show squirmer-type microswimmers can be noticeably enhanced as they are released move along surface pillar array, which constructed multiple pillars equal sizes spacing. An...

Ultrasonic water meters have current widespread problems of poor site adaptability, low measurement accuracy, and stability. A high-precision intelligent ultrasonic meter with self-diagnosis function adaptive technology was proposed in this paper, which is focus on improving the accuracy repeatability small pipe diameters. The hardware circuit design studied paper adopts low-power STM32L053 microcontroller Cortex-M0 core architecture 11 ps time resolution timing chip TDC-GP30 to complete...

The interaction between tumor cells and microenvironment during metastasis is mediated by the binding of cell surface receptors, such as integrins selectins, with protein ligands. Delineation their identification key receptors may be particularly important both in understanding extracellular matrix (ECM) remodeling developing potential therapeutic targets. Here we present a microfluidic chip that allows qualitative quantitative mapping large population cell-protein interactions. It was found...

Induced charge electroosmotic flow is a new electric driving mode. Based on the Navier–Stokes equations and Poisson–Nernst–Planck (PNP) ion transport equations, finite volume method adopted to calculate boundary conditions of induced flow. In this paper, formula zeta potential polarized solid surface proposed, UDF program suitable for simulation prepared according theory. At same time, basis theory, cross micropump driven by designed, voltage, potential, density, streamline are obtained....

Cigarette roundness is an important quality parameter in the tobacco industry. In order to solve problem that traditional industry measurement methods are time-consuming, laborious and inaccurate, a non-contact cigarette evaluation method based on least squares proposed evaluate end roundness. To accuracy, first initially identifies edge through Canny operator, then uses morphological closing operation eliminate burrs, fills inside of connectivity analysis, finally Sobel operator identify...

The coagulation behavior of nanoparticles in microfluidic chip channels is complex and affected by various external factors, including electric fields, sound wakes. Among them, fields have been confirmed to be the most effective for combining manipulating particles create new materials with diverse functionalities. In this work, characteristics field were studied, feasibility simplified Smoluchowski's equation (SE) Taylor-expansion moment method (TEMOM) when considering non-spherical...

Summary Cigarette draw resistance and filter pressure drop are both critical physical indicators for the tobacco industry, which use testing equipment to measure two parameters. Pressure standards used as transfer ensure accuracy reliability of equipment. generally cylindrical rods having a certain number parallel capillaries. To address issue how design fabricate quickly conveniently, this paper proposes method based on structural The uses mathematical model internal airflow standard...

To overcome the technical challenges of multi-blade centrifugal fan, such as low efficiency and insufficient total pressure, blades fan were optimally designed in this study. The flow field with a single-arc blade an airfoil was simulated compared using Computational Fluid Dynamics (CFDs). Under steady-state conditions, velocity distribution, aerodynamic performance analyzed. numerical results showed that there vortices, secondary flows, boundary layer separation phenomena passage fan. Based...

The induced-charge elecetroosmosis around conducting/Janus cylinder with arbitrary Debye thickness is studied numerically, when an direct current weak electric filed suddenly applied in a confined microchannel. It?s found that there are four large circulations the conducting cylinder, and total flux microchannel zero; two smaller Janus they compressed to wall. A bulk flux, which has parabolic relation field, also predicted.

Cylindrical microparticle transport and deposition from electrokinetic microflow in a 90 degree bend have been numerically simulated. Under the effect of dielectrohporetic force, gravity stokes it’s found that microparticles with larger size deposit on lower region bend’s outer wall. An exponential curve efficiency versus product number shape factor is fitted based large numerical results.

The liquid is usually driven by capillary force to flow forward in a channel network of point‐of‐care testing device. However, it not enough drive the that only relies on surface tension chip material itself. While drops into chip, unstable front shape may produce bubbles or flowing will even stop which resist signal detection. Here, novel method, hydrophilic coating, demonstrated. This method used an automatic device dip chips from self‐prepared TiO 2 sol forming gel film chips’ channel....

Electric force is the most popular technique for bioparticle transportation and manipulation in microfluidic systems. In this paper, iterative dipole moment (IDM) method was used to calculate dielectrophoretic (DEP) forces of particle-particle interactions a two-dimensional DC electric field, Lagrangian solve particles. It found that DEP properties whether connection line between initial positions particles perpendicular or parallel field greatly affect chain patterns. addition, dependence...

For the collision and coagulation of dielectric nanoparticles randomly oriented moving in an electric field, frequency function particles Stokes regime is derived. The numerical solution obtained by Taylor expansion moment method problem very consistent with previous study TEMOM model. In this paper, first-order ordinary differential equations are constructed to obtain closed-form expressions. fourth-order Runge-Kutta algorithm used derive particle concentration under different field...