A5006560011- Regulation of Appetite and Obesity
- Neuroendocrine regulation and behavior
- Circadian rhythm and melatonin
- Hypothalamic control of reproductive hormones
- Neurogenesis and neuroplasticity mechanisms
- Sleep and Wakefulness Research
- Identification and Quantification in Food
- Stress Responses and Cortisol
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Spaceflight effects on biology
- Hedgehog Signaling Pathway Studies
- Adipose Tissue and Metabolism
- Meat and Animal Product Quality
- Malaria Research and Control
- Birth, Development, and Health
- Mosquito-borne diseases and control
- SARS-CoV-2 and COVID-19 Research
- Cephalopods and Marine Biology
- Attention Deficit Hyperactivity Disorder
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- melanin and skin pigmentation
- Biochemical Analysis and Sensing Techniques
- Neuroinflammation and Neurodegeneration Mechanisms
Universidade de São Paulo
2017-2021
Sociedade Brasileira de Neurociências e Comportamento
2020
Autonomous University of Queretaro
2019
Universidad Nacional Autónoma de México
2019
Abstract The highly infective coronavirus disease 19 (COVID-19) is caused by a novel strain of coronaviruses – the severe acute respiratory syndrome 2 (SARS-CoV-2) discovered in December 2019 city Wuhan (Hubei Province, China). Remarkably, COVID-19 has rapidly spread across all continents and turned into public health emergency, which was ultimately declared as pandemic World Health Organization (WHO) early 2020. SARS-CoV-2 presents similar aspects to other members family, mainly regarding...
Abstract Melanin‐concentrating hormone (MCH) is a ubiquitous vertebrate neuropeptide predominantly synthesized by neurons of the diencephalon that can act through two G protein‐coupled receptors, called MCHR1 and MCHR2. The expression Mchr1 has been investigated in both rats mice, but its synthesis remains poorly described. After identifying an antibody detects with high specificity, we employed immunohistochemistry to map distribution CNS mice. Multiple neurochemical markers were also...
Abstract Melanin‐concentrating hormone (MCH) is a conserved neuropeptide, predominantly located in the diencephalon of vertebrates, and associated with wide range functions. While functional studies have focused on use traditional mouse laboratory model, critical gaps exist our understanding morphology MCH system this species. Even less known about nontraditional animal model Neotomodon alstoni (Mexican volcano mouse). A comparative morphological study among these rodents may, therefore,...
Abstract Although the melanin‐concentrating hormone ( MCH ) and its coding mRNA are predominantly found in tuberal hypothalamus, there is detectable synthesis of preoptic hypothalamus exclusively lactating dams, suggesting a participation alterations that take place after parturition. Also implicated dam physiology oxytocin, neurohormone released from posterior pituitary necessary for milk ejection. Because projection fields oxytocin‐immunoreactive (‐IR) neurones mediobasal overlap ‐IR...
Cerebral malaria (CM) is a severe immunovasculopathy which presents high mortality rate (15-20%), despite the availability of artemisinin-based therapy. More effective immunomodulatory and/or antiparasitic therapies are urgently needed. Experimental Malaria (ECM) in mice used to elucidate aspects involved this pathology since manifests many neurological features CM. In present study, we evaluated potential mechanisms protection afforded by perillyl alcohol (POH) mouse strains susceptible CM...
Urocortin 3 [UCN3] is a neuropeptide member of the corticotrophin-releasing factor [CRF] peptide family that acts as selective endogenous ligand for CRF2 receptor. Immunohistochemistry and in situ hybridization data from rodents revealed UCN3-containing neurones discrete regions CNS, such medial preoptic nucleus, rostral perifornical area, nucleus amygdala superior paraolivary nucleus. UCN3-immunoreactive [UCN3-ir] terminals are distributed throughout mostly overlap with mRNA expression....
Lactation is a complex physiological process, depending on orchestrated central and peripheral events, including substantial brain plasticity. Among these events novel expression of pro-melanin-concentrating hormone (Pmch) mRNA in the rodent hypothalamus, such as ventral part medial preoptic area (vmMPOA). This reaches its highest levels around postpartum day 19 (PPD19), when dams transition from lactation to weaning period. The appearance this lactation-related Pmch occurs simultaneously...
Abstract Melanin-concentrating hormone (MCH) is a ubiquitous vertebrate neuropeptide predominantly synthesized by neurons of the diencephalon that can act through two G protein-coupled receptors, called MCHR1 and MCHR2. The expression Mchr1 has been investigated in both rats mice, but its synthesis remains poorly described. After identifying an antibody detects with high specificity, we employed immunohistochemistry to map distribution CNS mice. Multiple neurochemical markers were also...