A5091495583- Visual perception and processing mechanisms
- Ophthalmology and Visual Impairment Studies
- Neuroscience and Neural Engineering
- Glaucoma and retinal disorders
- Neural dynamics and brain function
- Retinal Development and Disorders
- Transcranial Magnetic Stimulation Studies
- Neuroscience and Neuropharmacology Research
- Photoreceptor and optogenetics research
- Ocular and Laser Science Research
- Spatial Neglect and Hemispheric Dysfunction
- Vestibular and auditory disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Functional Brain Connectivity Studies
- Ophthalmology and Eye Disorders
- EEG and Brain-Computer Interfaces
- Nanoparticle-Based Drug Delivery
- Hallucinations in medical conditions
- Retinal Diseases and Treatments
- Neurological disorders and treatments
- Retinal Imaging and Analysis
- Migraine and Headache Studies
- Neural and Behavioral Psychology Studies
- Retinal and Optic Conditions
- Neurotransmitter Receptor Influence on Behavior
Otto-von-Guericke University Magdeburg
2015-2024
University Hospital Magdeburg
2004-2024
Center for Behavioral Brain Sciences
2017-2023
Chengdu University
2019
Software (Spain)
2018
Shandong Institute of Automation
2012-2015
Chinese Academy of Sciences
2012-2015
Beijing Tongren Hospital
2012-2015
Capital Medical University
2012-2015
German Center for Neurodegenerative Diseases
2014
Partial blindness after visual system damage is considered irreversible, yet the brain has residual capacities and considerable plasticity potential. We now applied non-invasive alternating current stimulation (ACS) to of patients with optic nerve aim induce recovery functions.In a prospective, double-blind, randomized, placebo-controlled clinical trial several year old partial lesions were treated ACS (n = 12) or placebo-stimulation 10). was delivered transorbitally for 40 minutes on 10...
<h3>Objective:</h3> To characterize brain functional connectivity in subjects with prechiasmatic visual system damage and relate features to extent of vision loss. <h3>Methods:</h3> In this case-control study, resting-state, eyes-closed EEG activity was recorded patients partial optic nerve (n = 15) uninjured controls 13). We analyzed power density (coherence, Granger causality), the latter as (1) between-areal coupling strength (2) individually thresholded binary graphs. Functional then...
Background Vision loss after optic neuropathy is considered irreversible. Here, repetitive transorbital alternating current stimulation (rtACS) was applied in partially blind patients with the goal of activating their residual vision. Methods We conducted a multicenter, prospective, randomized, double-blind, sham-controlled trial an ambulatory setting daily application rtACS (n = 45) or sham-stimulation 37) for 50 min duration 10 week days. A volunteer sample nerve damage (mean age 59.1 yrs)...
Reducing intraocular pressure (IOP) in primary open-angle glaucoma (POAG) is currently the only approach to prevent further optic nerve head damage. However, other mechanisms such as ischemia, oxidative stress, glutamate excitotoxicity, neurotrophin loss, inflammation/glial activation, and vascular dysregulation are not addressed. Because stress a key risk factor affecting these mechanisms, we evaluated whether mindfulness-based reduction can lower IOP normalize typical biomarkers.In...
ABSTRACT Background Integrity of academic publishing is increasingly undermined by fake science publications massively produced commercial “editing services” (so-called “paper mills”). They use AI-supported, automated production techniques at scale and sell to students, scientists, physicians under pressure advance their careers. Because the in biomedicine unknown, we developed a simple method red-flag them estimate number. Methods To identify indicators able (RFPs), sent questionnaires...
Adult rats with bilateral lesions of the caudate nucleus were treated G M1 ganglioside. Although animals injected a control solution severely impaired in their ability to learn complex spatial task, those ganglioside able reversals.
Brain damage is often accompanied by homonymous hemianopia, but few therapeutic approaches exist for visual field deficits. In this open pilot study we describe a computerized training program which may possibly reduce the size of 'blind'
To evaluate vision-related and health-related quality of life (VRQoL, HRQoL) in first stroke patients with homonymous visual field defects (VFD) respect to the extent lesion. Since VFD occur approximately 10% main purpose study was investigate additional impact hypothesizing that causes diminished VRQoL. In 177 persisting 2.5 years after posterior-parietal lesions VRQoL assessed by National-Eye-Institute-Visual-Functioning-Questionnaire (NEI-VFQ) HRQoL Medical-Outcome-Study Short-Form-36...
Abstract Glaucoma is not only an eye disease but also associated with degeneration of brain structures. We now investigated the pattern visual and non-visual structural changes in 25 primary open angle glaucoma (POAG) patients age-gender-matched normal controls using T1-weighted imaging. MRI images were subjected to volume-based analysis (VBA) surface-based (SBA) whole as well ROI-based lateral geniculate nucleus (LGN), cortex (V1/2), amygdala hippocampus. While VBA showed no significant...