Axel J. Giudicatti

ORCID: 0000-0002-4496-7091
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About
Contact & Profiles
Research Areas
  • Plant Molecular Biology Research
  • Plant Stress Responses and Tolerance
  • Photosynthetic Processes and Mechanisms
  • Plant Parasitism and Resistance
  • RNA Research and Splicing
  • RNA modifications and cancer
  • Plant Pathogenic Bacteria Studies
  • Light effects on plants
  • Plant Disease Resistance and Genetics
  • Plant-Microbe Interactions and Immunity
  • MicroRNA in disease regulation
  • Plant nutrient uptake and metabolism
  • Chromosomal and Genetic Variations

Instituto de Agrobiotecnología del Litoral
2018-2024

National University of the Littoral
2020-2024

Consejo Nacional de Investigaciones Científicas y Técnicas
2022

Abstract The regulation of microRNA (miRNA) biogenesis is crucial for maintaining plant homeostasis under biotic and abiotic stress. crosstalk between the RNA polymerase II (Pol-II) complex miRNA processing machinery has emerged as a central hub modulating transcription cotranscriptional primary transcripts (pri-miRNAs). However, it remains unclear how miRNA-specific transcriptional regulators recognize MIRNA loci. Here, we show that Arabidopsis (Arabidopsis thaliana) HIGH EXPRESSION OF...

10.1093/plcell/koad132 article EN cc-by-nc-nd The Plant Cell 2023-05-17

The study of RNAs has become one the most influential research fields in contemporary biology and biomedicine. In last few years, new sequencing technologies have produced an explosion exciting discoveries field but also given rise to many open questions. Defining these questions, together with old, long-standing gaps our knowledge, is spirit this article. breadth topics within RNA vast, every aspect molecules contains countless Here, we asked 12 groups discuss their compelling question...

10.1093/plcell/koac346 article EN The Plant Cell 2022-12-08

Abstract Bacteria inject effector proteins into host cells to manipulate cellular processes that promote disease. Since bacteria deliver minuscule amounts of effectors only targeted cells, it is technically challenging capture effector-dependent changes from bulk-infected tissues. Here, we report a new technique called effector-inducible isolation nuclei tagged in specific cell types (eINTACT), which facilitates affinity-based purification Arabidopsis plant have received Xanthomonas...

10.1038/s41477-022-01302-y article EN cc-by Nature Plants 2022-12-22

MicroRNAs are small regulatory RNAs involved in several processes plants ranging from development and stress responses to defense against pathogens. In order accomplish their molecular functions, miRNAs methylated loaded into one ARGONAUTE (AGO) protein, commonly known as AGO1, stabilize protect the molecule assemble a functional RNA-induced silencing complex (RISC). A specific machinery controls miRNA turnover ensure release of targeted-genes given circumstances. The trimming tailing...

10.3390/plants10020267 article EN cc-by Plants 2021-01-30

A delicate balance in gene expression, a process highly controlled by post-transcriptional silencing mediated miRNAs, is vital during plant growth and responses to stress. Within the miRNA biogenesis pathway, HYL1 one of most important proteins, initially recognized for its role as cofactor DCL1. Yet, HYL1's functions extend beyond processing, encompassing transcriptional regulation protein translation between other recently discovered functions. This review comprehensively examines our...

10.1016/j.pbi.2024.102546 article EN cc-by-nc-nd Current Opinion in Plant Biology 2024-05-07
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