A5057266932- Pelvic floor disorders treatments
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Urological Disorders and Treatments
- Prostate Cancer Treatment and Research
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Diagnosis and Treatment
- Urologic and reproductive health conditions
- Urinary and Genital Oncology Studies
- Anorectal Disease Treatments and Outcomes
- Glycosylation and Glycoproteins Research
- Genital Health and Disease
- Monoclonal and Polyclonal Antibodies Research
- Pelvic and Acetabular Injuries
- Pregnancy-related medical research
- Health Promotion and Cardiovascular Prevention
- Proteoglycans and glycosaminoglycans research
- Multiple and Secondary Primary Cancers
- Cancer, Hypoxia, and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
- Diagnosis and Treatment of Venous Diseases
- Diverticular Disease and Complications
- Advanced Proteomics Techniques and Applications
- Cancer Immunotherapy and Biomarkers
- Phytoestrogen effects and research
Kyorin University
2004-2024
Yotsuya Medical Cube
2016
Vaginal childbirth may result in vaginal introital laxity, altered genital sensation during sexual intercourse, and reduced satisfaction. We report the long-term effectiveness of a single nonsurgical procedure with radiofrequency (RF) energy for laxity at introitus.Prospective single-arm study 30 premenopausal women (21-52 year) one 30-minute office using RF applied to introitus; 12-month outcome assessments included linguistic validated Japanese versions Female Sexual Function Index (FSFI)...
Objectives To compare persistence with medication and the reasons for discontinuation of mirabegron or solifenacin therapy up to12 months in women overactive bladder ( OAB ). Methods Female patients who presented to women's urology clinics were enrolled a prospective, randomized, two‐arm study. Patients randomized receive at 25–50 mg n = 76) 2.5–5 72). The rate investigated 12 months. Results 12‐month was 12.2% group versus 20.1% there no significant differences rates during study (n.s)....
Accurate cystoscopic recognition of Hunner lesions (HLs) is indispensable for better treatment prognosis in managing patients with Hunner-type interstitial cystitis (HIC), but frequently challenging due to its varying appearance.To develop a deep learning (DL) system HL using artificial intelligence (AI).A total 626 images collected from January 8, 2019 December 24, 2020, consisting 360 HLs 41 HIC and 266 flat reddish mucosal resembling control including those bladder cancer other chronic...
Abstract Aim This study aimed to evaluate sexual activity and quality of life (QOL) after transvaginal mesh (TVM) surgery in Japanese patients with pelvic organ prolapse (POP). The objective cure rate associated complications were also investigated. Methods cases who underwent TVM retrospectively analyzed. QOL was assessed using the Prolapse Quality Life Questionnaire (P‐QOL), function evaluated Female Sexual Function Index (FSFI) before 12 months surgery. Results A total 237 completed...
Overexpression of the HER2 receptor protein and amplification gene has been implicated in tumor development progression, associated with a poor prognosis several types cancer. The aim this study was to evaluate whether pretreatment serum levels can be used predict biochemical recurrence-free survival prostate cancer patients about undergo endocrine therapy.The population consisted 379 untreated histologically diagnosed cancer: 197 T2N0M0, 93 T3N0M0, 19 TxN1Mx, 70 TxNxM1. Serum were assessed...
In 2005, a new minimally invasive procedure, the tissue fixation system (TFS) was reported. Like TVT (tension-free vaginal tape), TFS works by creating foreign body collagenous reaction that reinforces weakened pelvic ligament. The objective to assess effectiveness and perioperative safety of in day surgery clinic for treatment organ prolapse (POP).The tape applied tunnel adjacent natural ligaments repair anterior cervical ring cardinal ligament, paravaginal tissues uterosacral under local...
To determine whether MUC7 gene expression can be used as a bladder cancer marker in peripheral blood.Nested reverse transcription-polymerase chain reaction (RT-PCR) was performed on four types of cell lines (RT4, T24, EJ-1 and TCC) the blood 38 (31 superficial disease seven invasive disease) patients 18 subjects with urinary tract infections or other non-malignant conditions to MUC7.No detected control subjects. MUC7-positive cells were all (47.4%) samples patients. Based tumor stage, 11 29...
Abstract Background Although the albumin-to-globulin ratio (AGR) is a promising biomarker for various malignancies, few studies have investigated its prognostic significance upper tract urothelial carcinoma (UTUC). Methods This retrospective study conformed to REporting recommendations tumour MARKer (REMARK) guideline. We reviewed 179 patients with UTUC who underwent radical nephroureterectomy at our institution between 2008 and 2018. Associations of preoperative clinicopathological factors,...
<b><i>Background:</i></b> Treatment of overactive bladder (OAB) with antimuscarinic agents has been shown to improve depression and/or anxiety symptoms. <b><i>Objectives:</i></b> The aim this study was evaluate the efficacy mirabegron on OAB symptoms and its effects treatment-naïve women OAB. <b><i>Methods:</i></b> Women treated were prospectively evaluated by symptom score hospital Scale before at 4 8 weeks after...
The nested reverse transcription polymerase chain reaction (RT-PCR) method was used to determine expression of uroplakin II (UP II) or cytokeratin 20 (CK-20) in cells separated from the peripheral blood patients with urothelial cancer. We examine whether UP CK-20 can be as a cancer marker for isolated blood.Peripheral taken healthy volunteers without history cancer, 10 negative bladder biopsy and 108 Results RT-PCR assay were compared pathological stage recurrence.None samples control...
To compare the ratio of free prostate specific antigen (fPSA), total PSA (tPSA) and complexed (cPSA, measured using a novel immunoassay) with other variables used to detect cancer in patients intermediate serum levels 4.1-10.0 ng/mL.From July 1997 August 1998, 140 consecutive were assessed; all had and/or abnormal findings on digital rectal examination. All underwent transrectal ultrasonography (TRUS)-guided biopsy, transition zone volumes determined by TRUS. Free tPSA Tandem-R assay...
Abstract Objectives: We determine whether the different molecular forms of prostate‐specific antigen (PSA) and other PSA variables can predict prostate cancer in men undergoing repeat needle biopsy. Methods: Between 1997 2001, biopsy was performed 97 patients who had undergone prior negative The ability total (tPSA), complexed (cPSA), free (fPSA), free‐to‐total (fPSA/tPSA), free‐to‐complexed (fPSA/cPSA), complexed‐to‐total (cPSA/tPSA), tPSA density (tPSAD), cPSA (cPSAD), transition zone...
Abstract Background Adenosquamous carcinoma of the prostate (ASCP) is an extremely rare and aggressive cancer variant, whose genomic characteristics have not been elucidated. Although liquid biopsy circulating tumor cells (CTCs) emerging topic in oncology, no study has assessed CTCs patients with ASCP. Case presentation. A 76-year-old man presented discomfort his urethra. His prostate-specific antigen (PSA) level was 13.37 ng/mL. computed tomography (CT) scan indicated a mass multiple lymph...
Since pheochromocytomas present with various complications due to catecholamine hypersecretion, their perioperative management needs special attention.A 45-year-old man visited our hospital a complaint of abdominal swelling. Radiological and endocrinological assessments determined the tumor as giant (>20 cm) cystic pheochromocytoma. After administration doxazosin, patient underwent radical surgery. was extremely large fixed surrounding structures, we punctured it aspirated fluid improve...
Urinary incontinence (UI) is a common health-related problem in the female population and has negative impact on many aspects of patients' quality life including mental problems. This study evaluated effects mid-urethral sling (MUS) surgery patients with stress UI or UI-dominant mixed UI.Women who underwent MUS were enrolled this followed up for 12 months. The International Consultation Incontinence Questionnaire-Short Form (ICIQ-SF) Hospital Anxiety Depression Scale (HADS) at baseline...
While gemcitabine/cisplatin (GC) is the gold standard regimen for patients with advanced urothelial carcinoma (aUC), either dose-reduced GC or gemcitabine/carboplatin (GCa) an alternative option "cisplatin-unfit" patients. However, few studies have compared outcomes these commonly used regimens in real-world setting.We retrospectively reviewed aUC who received full-dose GC, GCa as first-line salvage chemotherapy at two university hospitals between 2016 and 2020. Progression-free survival,...
We aimed to assess the relationships between lower urinary tract symptoms (LUTS) and various parameters including diabetes complications in patients with type 2 diabetes.