Qian-Qian Huang

ORCID: 0000-0002-4517-7606
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Metal-Catalyzed Oxygenation Mechanisms
  • Metal complexes synthesis and properties
  • Crystallography and molecular interactions
  • Magnetism in coordination complexes
  • Advanced Nanomaterials in Catalysis
  • Nanoplatforms for cancer theranostics
  • Vascular anomalies and interventions
  • Traditional Chinese Medicine Analysis
  • Photosynthetic Processes and Mechanisms
  • Thermal Expansion and Ionic Conductivity
  • Microbial metabolism and enzyme function
  • Liver Disease Diagnosis and Treatment
  • Enzyme-mediated dye degradation
  • Advanced Photocatalysis Techniques
  • Flavonoids in Medical Research
  • Stoma care and complications
  • Ferroelectric and Piezoelectric Materials
  • Adipose Tissue and Metabolism
  • Endoplasmic Reticulum Stress and Disease
  • Colorectal Cancer Surgical Treatments
  • Phosphodiesterase function and regulation
  • Biochemical and biochemical processes
  • Saffron Plant Research Studies

Xinxiang Medical University
2017-2024

Nanchang University
2024

Tongde Hospital of Zhejiang Province
2024

Dalian University of Technology
2013-2017

Hubei University of Chinese Medicine
2017

Henan University of Traditional Chinese Medicine
2015

NIST Center for Neutron Research
2011

Chinese Academy of Medical Sciences & Peking Union Medical College
2009

University of Oslo
1999

A series of flavonolate complexes [M(II)L(fla)] (M = Mn (1), Fe (2), Co (3), Ni (4), Cu (5), and Zn (6), LH: 2-{[bis(pyridin-2-ylmethyl)amino]methyl}benzoic acid, fla: flavonolate) have been synthesized as structural functional models for the ES (enzyme-substrate) active site various M(II)-containing quercetin 2,3-dioxygenase (2,3-QD) their structures, spectroscopic features, redox properties, well reactivity toward molecular oxygen, investigated. The metal centers [Fe(II)L(fla)]·H2O...

10.1021/ic400972k article EN Inorganic Chemistry 2013-09-17

A series of mononuclear CoII–flavonolate complexes [CoIILR(fla)] (LRH = 2-{[bis(pyridin-2-ylmethyl)amino]methyl}-p/m-R-benzoic acid; R p-OMe (1), p-Me (2), m-Br (4), and m-NO2 (5); fla flavonolate) were designed synthesized as structural functional models for the ES (enzyme–substrate) to mimic active site Co(II)-containing quercetin 2,3-dioxygenase (Co–2,3-QD). The metal center Co(II) ion in each complex shows a similar distorted octahedral geometry. model display high enzyme-type...

10.1021/ic402695c article EN Inorganic Chemistry 2014-03-06

NiII-flavonolate complexes [NiIILR(fla)] (LRH: 2-{[bis(pyridin-2-ylmethyl)amino]methyl}-p/m-R-benzoic acid, R: p-OMe (1), p-Me (2), m-Br (4) and m-NO2 (5), fla: flavonolate) were synthesized characterized with relevance to structural functional models for the ES (enzyme–substrate) adduct of NiII-containing quercetin 2,3-dioxygenase (2,3-QD). Their structures, spectroscopic features, redox properties reactivity toward molecular oxygen have been investigated. The show a similar distorted...

10.1039/c3dt53349b article EN Dalton Transactions 2014-01-01

Ferrous and sulfur ions are essential elements for the human body, which play an active role in maintaining body's normal physiology. Meanwhile, mussel-inspired polydopamine (PDA) possesses good hydrophilicity biocompatibility. In present work, ferrous sulfide embedded into nanoparticles (PDA@FeS NPs) was designed synthesized via a simple predoping polymerization-coprecipitation strategy intelligent PDA matrix successfully prevented oxidation agglomeration of FeS nanoparticles. Importantly,...

10.1039/d2dt03765c article EN Dalton Transactions 2023-01-01

Abstract Asprosin (ASP) is a newly‐identified adipokine and plays important roles in energy metabolism homeostasis. However, there no report on whether how ASP involved the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Therefore, study, we investigated protective effects ASP‐deficiency NAFLD model mice detrimental treatment human normal hepatocytes (LO2 cell line). More important, explored underlying mechanism from perspective lipid inflammation. In vivo experiments, our data...

10.1002/ddr.22213 article EN Drug Development Research 2024-05-27

[M<sup>II</sup>L(OAc)] (M: Mn, Fe, Co, Ni, Cu and Zn) are reported as the models of various M<sup>II</sup>-substituted quercetin 2,3-dioxygenase.

10.1039/c5dt01760b article EN Dalton Transactions 2015-01-01

With the aim of revealing catalytic role atypically coordinated (3His-1Glu) active site mononuclear non-heme Fe(II)-dependent quercetin 2,4-dioxygenase (Fe-2,4-QD) and electronic effects model ligands on reactivity toward dioxygen, a set p/m-R-substituted carboxylate-containing ligand-supported Fe(II)-3-hydroxyflavonolate complexes, [FeIILR(fla)] (LRH: 2-{[bis(pyridin-2-ylmethyl)amino]methyl}-p/m-R-benzoic acid; R: p-OMe (1), p-Me (2), m-Br (4), m-NO2 (5); fla: 3-hydroxyflavonolate), were...

10.1021/acsomega.7b00927 article EN publisher-specific-oa ACS Omega 2017-09-18

Hydrophilic ionic liquids are often used to extract the active ingredients of medicinal plants, while hydrophobic rarely directly solid samples. In this paper, a simple, novel and efficient temperature-controlled liquids-based ultrasound/heating-assisted extraction (TC-ILs-UHAE) procedure coupled with high-performance liquid chromatography (HPLC) was developed applied determination ferulic acid (FA) in Chinese herbal medicine Angelica sinensis. During procedure, (ILs) were dispersed into...

10.3390/molecules25153356 article EN cc-by Molecules 2020-07-24

Pueraria lobata, Salvia miltiorrhiza and Panax notoginseng are traditional Chinese medicines which have been used for thousands of years either singly or in combination. However, the quality formulas containing all part three herbs is, at present, controlled by only one two easily detectable compounds.. A rapid resolution liquid chromatography (RRLC) method has developed control combination through ten active ingredients originating from raw herbs. The analysis was achieved a run less than...

10.1177/1934578x1701200930 article EN Natural Product Communications 2017-09-01

Fazit Die Ergebnisse dieses Erfahrungsberichts belegen, dass die endovaskuläre Behandlung eines primären vollständigen Verschlusses der V. cava inferior sicher und erfolgreich ist.

10.1055/s-0034-1393468 article DE Interventionelle Radiologie Scan 2015-11-13
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