Due to the Covid-19 pandemic, National Taiwan University anatomy teachers adopted asynchronous online video teaching and reduced size of laboratory groups in April 2020. The aim this study was investigate impact these changes on medical students' learning. Before Covid-19, performance 2019-2020 cohort significantly better than that 2018-2019 cohort. However, implementation modified strategies lowered midterm score second semester. Conversely, final examination higher Through correlation...

Familial amyloid polyneuropathy (FAP) due to amyloidogenic transthyretin (TTR) is often associated with impairment of thermonociceptive functions. This study investigated skin innervation and its clinical significance in genetically defined FAP a hot-spot Ala97Ser TTR mutation (Ala97Ser).Skin biopsies were performed on the distal leg patients Ala97Ser, intraepidermal nerve fiber (IENF) densities quantified.There 19 unrelated manifesting late-onset (59.47 +/- 5.70 years) generalized...

Certain plant phenolic compounds and monosaccharides induce the transcription of virulence (vir) genes Agrobacterium tumefaciens through VirA-VirG two-component regulatory system. The product chromosomal gene chvE is homologous to galactose-binding protein Escherichia coli required for vir induction by sugars. Adjacent to, but divergent in from, an open reading frame, now termed gbpR (galactose-binding regulator), that LysR family transcriptional regulators. chvE::lacZ expression was induced...

Liver is unique in its capability to regenerate after an injury. regeneration a 2/3 partial hepatectomy served as classical model and adopted frequently study the mechanism of liver regeneration. In present study, semiquantitative analysis protein expression mouse following was performed using iTRAQ technique. Proteins from pre-PHx control livers regenerating for 24, 48 72 h were extracted inspected 4-plex isotope labeling, followed by liquid chromatography fractionation, mass spectrometry...

It can be difficult for some students to learn three-dimensional anatomical structure concepts. While virtual reality (VR) systems have been reported as helpful learning, there has scarce research on either VR teaching strategies or the influence of visually induced motion sickness (VIMS) in context large anatomy classes (i.e., over 100 students). The study thus aimed (1) establish a instruction video class; (2) determine how many experience VIMS when watching video; (3) evaluate video-based...

A novel tunable inductor with an extremely high Q is described. The consists of coupled RF and drive coils, which employs phase shifting the mutual components demonstrates measured results over 100% inductance tuning a significant decrease in resistive losses resulting about 2000.

Abstract Delivering gene constructs into the dorsal root ganglia (DRG) is a powerful but challenging therapeutic strategy for sensory disorders affecting DRG and their peripheral processes. The current delivery methods of direct intra-DRG injection intrathecal have several disadvantages, including potential injury to neurons low transfection efficiency, respectively. This study aimed develop spinal nerve deliver polyethylenimine mixed with plasmid (PEI/DNA polyplexes) containing green...

We assessed the effects of treatment with 4-methylcatechol (4MC), a known inducer nerve growth factor, on peripheral regeneration by analyzing cutaneous and muscular reinnervation in mice after sciatic crush injury. At 3 months postinjury, skin innervation index was significantly higher 4MC group than control (p=0.0002); there also increased unmyelinated fiber density (p=0.0042) fibers/Remak bundle (p = 0.001) sural nerves, indicating regeneration. These changes were accompanied increases...

Population-based data for diabetic hand syndrome (DHS) are limited. The aim of the present epidemiological study was to estimate overall and cause-specific prevalence rate ratio (RR) DHS in patients with diabetes.The a cross-sectional based on random sample 57 093 diabetics matched controls, both identified from Taiwan National Health Insurance claims 2010. analyzed included carpal tunnel (CTS), stenosing flexor tenosynovitis (SFT), limited joint mobility (LJM), Dupuytren's disease (DD).The...

The purpose of this study was to understand the situation diabetes patients receiving examinations for complications and explore factors influencing their intention receive complications.A cross-sectional performed that included 251 who visited outpatient clinics in Southern Taiwan. A survey using a self-administered questionnaire conducted from October 2015 January 2016. items on demographic characteristics, perceived susceptibility complications, seriousness benefits taking action...

Background: To investigate all-cause and cause-specific mortality in Taiwanese patients with type 1 diabetes.

Registered nurses are required for high-quality healthcare. Thus, the anatomy course is essential regarding professional knowledge of human body during nursing training process. However, previous studies have indicated that teaching time and teachers were reduced insufficient. Therefore, to improve learning practical in response these difficulties, a bilingual National Taiwan University web-based atlas (NTU-WAA) was created as cross-platform application its feasibility evaluated.The...

This study focused on identifying the signalling mediating effect of magnolol corticosterone production. Magnolol‐induced production was completely inhibited by mitogen‐activated protein kinase (MEK)‐inhibitor PD98059, tyrosine (TK)‐inhibitor genistein or Janus 2 (JAK2)‐inhibitor AG490, suggesting that extracellular signal‐regulated (ERK) and JAK2 are both involved in this signaling cascade. Further, induced transient phosphorylation MEK, ERK, cAMP response‐element binding (CREB) expression...

Modified teaching strategies (MTS), asynchronous online and smaller dissection groups, were applied to a gross anatomy course for dental students in the National Taiwan University April 2020 response COVID-19 pandemic. This study aimed investigate effects perceptions of MTS on students.Scores examinations 2018-2019 (without MTS) 2019-2020 (with cohorts compared explore effect academic performance. Moreover, questionnaire from cohort was analysed determine students' about MTS.The lecture...

We present designs to achieve monolithic integration of high-Q spiral inductors and bandpass filters (BPFs) in standard CMOS technology. The designed transformer-type inductor behaves like an ideal due the active magnetic feedback from secondary coil for compensating energy loss primary coil. This approach is compatible with mainstream IC technologies has potential reactance low power, noise high linearity. fabricated exhibit Q/spl sim/3000 between 1.5 2.1 GHz. BPF shows 3 dB bandwidth 120...

Recently the semiconductor industry tends to develop a smaller volume device and system with lower power consumption, leakage current, high speed performance. SOI technology has many unique characteristics, which is one of most promising methods direction. As memory concerned, 1T-DRAM cell realized by concept floating body effect in PD-SOI nMOSFET can allow DRAM be scaled down depth less area occupied. In this paper, we propose new structure cell, bottom buried oxide sidewall block around...

To compare occupational exposure to extremely-low-frequency magnetic field (ELF-MF) between dentists practicing in dental clinics and those employed hospitals.Thirty-two who worked at (n=15) 33 hospital departments (n=7) voluntarily provided their informed consent participate this measurement study. The study were requested wear an ELF-MF dosimeter for some 3 h work determine personal exposure. Spot measurements taken a number of locations each office used indicate the environment level....

Abstract Gross anatomy and neuroanatomy are fundamental subjects in medical education. However, learning different anatomical terms understanding the complexity of often challenging for students. At National Taiwan University, 2020–2021 cohort adopted a face‐to‐face (F2F) strategy gross lecture laboratory courses until May 17, 2021. After aforementioned date, same learned rest via asynchronous online learning. This study aimed to evaluate benefits students' preferences F2F strategies...

Objective Although the microenvironment for peripheral nerve regeneration is permissive, such a mechanism defective in diabetes, and molecular mediators remain elusive. [Correction added on May 11, 2022, after first online publication: In preceding sentence, “is ok” was changed to defective”.] This study aimed (1) investigate relationship between skin innervation collagen pathology diabetic neuropathy (2) clarify alterations that occur response hyperglycemia their effects axon regeneration....