- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Dermatological and Skeletal Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Nonmelanoma Skin Cancer Studies
- Kidney Stones and Urolithiasis Treatments
- Cancer and Skin Lesions
- Botulinum Toxin and Related Neurological Disorders
- Urinary and Genital Oncology Studies
- Cutaneous Melanoma Detection and Management
- Pediatric Urology and Nephrology Studies
- Nerve injury and regeneration
- Bladder and Urothelial Cancer Treatments
- Urological Disorders and Treatments
- Galectins and Cancer Biology
- Pain Mechanisms and Treatments
National Taiwan University
2022-2025
Kaohsiung Medical University
2022-2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2022-2025
Kaohsiung Municipal Hsiao-Kang Hospital
2022-2023
Abstract Hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) is a neurodegenerative disease caused by mutations in the gene encoding (TTR). Despite amyloid deposition being pathognomonic for diagnosis, this pathology nervous tissues cannot fully account nerve degeneration, implying additional pathophysiology neurodegeneration, which, however, has not yet been elucidated. In study, neuroinflammation ATTRv-PN was investigated examining morphometry, blood-nerve barrier, and...
Abstract Objective Despite amyloid deposition as a hallmark of hereditary transthyretin amyloidosis (ATTRv) with polyneuropathy, this pathology could not completely account for nerve degeneration. ATTRv patients frequently have vasomotor symptoms, but microangiopathy hypothesis in was systemically clarified. Methods This study examined the vascular sural nerves (TTR) mutation p.Ala117Ser (TTR‐A97S), focusing on morphometry and patterns molecular expression relation to We further applied...
High-dose-rate (HDR) electronic brachytherapy (EBT) has been shown to be effective for non-melanoma skin cancer (NMSC) in Caucasian patients. However, its efficacy remains unknown Asian To analyze the clinical outcome of HDR EBT NMSC a Taiwanese medical center.Medical records over 5-year period between January 2015 December 2019 were retrospectively analyzed.Forty-seven patients with 54 including 42 basal cell carcinomas (BCCs) and 12 squamous (SCCs) treated EBT. The average age was 73.8...
(1) Background: The current gold standard treatment of bladder cancer is conventional transurethral resection the tumor (CTURBT) using monopolar or bipolar resectoscopes. Laser en-bloc (LERBT) could achieve a higher quality specimen, reduce perioperative complications, and decrease recurrence rate. Here, we compare efficacy safety Vela laser versus monopolar/bipolar resection; (2) Methods: A total 100 clinically cT1-2 patients with were retrospectively reviewed in this study. Among these...
Objective Although the microenvironment for peripheral nerve regeneration is permissive, such a mechanism defective in diabetes, and molecular mediators remain elusive. [Correction added on May 11, 2022, after first online publication: In preceding sentence, “is ok” was changed to defective”.] This study aimed (1) investigate relationship between skin innervation collagen pathology diabetic neuropathy (2) clarify alterations that occur response hyperglycemia their effects axon regeneration....