Jia‐In Lee

ORCID: 0000-0002-0679-6471
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About
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Research Areas
  • Pediatric Urology and Nephrology Studies
  • Kidney Stones and Urolithiasis Treatments
  • Mental Health Treatment and Access
  • Suicide and Self-Harm Studies
  • Urological Disorders and Treatments
  • Eating Disorders and Behaviors
  • Impact of Technology on Adolescents
  • LGBTQ Health, Identity, and Policy
  • Sexuality, Behavior, and Technology
  • Nutrition and Health in Aging
  • Eosinophilic Esophagitis
  • Connexins and lens biology
  • Bone health and osteoporosis research
  • Health disparities and outcomes
  • Mobile Health and mHealth Applications
  • Psychosomatic Disorders and Their Treatments
  • Retinal Diseases and Treatments
  • Family Caregiving in Mental Illness
  • Lipid metabolism and disorders
  • Sex and Gender in Healthcare
  • Therapeutic Uses of Natural Elements
  • Child and Adolescent Psychosocial and Emotional Development
  • Obesity and Health Practices
  • Cancer-related molecular mechanisms research
  • Bullying, Victimization, and Aggression

Kaohsiung Medical University
2010-2025

Kaohsiung Medical University Chung-Ho Memorial Hospital
2015-2025

Brigham and Women's Hospital
2020-2021

Harvard University
2020

Phu Yen University
2019

Abstract This study investigates the correlation between body mass index (BMI) and osteoporosis utilizing data from Taiwan Biobank. Initially, a comprehensive analysis of 119,009 participants enrolled 2008 to 2019 was conducted assess association BMI prevalence. Subsequently, longitudinal cohort 24,507 participants, initially free osteoporosis, underwent regular follow-ups every 2–4 years analyze risk development, which subset main cohort. Participants were categorized into four groups:...

10.1038/s41598-024-59159-4 article EN cc-by Scientific Reports 2024-04-12

We aimed to examine the association between metabolic syndrome and risk of kidney stone development in a large-scale community-based cohort. A total 121,579 participants enrolled Taiwan Biobank were analyzed. They divided into two groups on basis presence syndrome. The disease was defined by self-reported history stones. mean age 50 years old, stones observed 3446 (10%) 4292 (5%) with without syndrome, respectively. Higher prevalence found compared those (odds ratio (OR), 1.32; 95%...

10.3390/jpm11111154 article EN Journal of Personalized Medicine 2021-11-06

(1) Background: We aimed to explore the associations between menopause, postmenopausal hormone therapy, and metabolic syndrome in a large community-based group of Asian women. (2) Methods: This is cross-sectional study which we enrolled women aged 30 70 years with sufficient information about menopausal status from Taiwan Biobank. The definition for used this aligns Bureau Health Promotion’s (Taiwan) proposed definition. (3) Results: A total 17,460 were recruited. had higher prevalence (30%...

10.3390/jcm12134435 article EN Journal of Clinical Medicine 2023-06-30

Abstract Smoking is the most important risk factor for chronic obstructive pulmonary disease (COPD), however evidence from large-scale studies on whether secondhand smoke (SHS) increases of COPD still lacking. We conducted this large longitudinal study to investigate association between SHS and development COPD. This a study. Data 6519 subjects who were never-smokers, had no history COPD, complete lung function records extracted Taiwan Biobank. They divided into two groups according...

10.1038/s41598-024-58038-2 article EN cc-by Scientific Reports 2024-03-29

Internalized sexual stigma (ISS) is one of the major issues that can compromise health minority populations. This quantitative study aimed to examine: (1) relationships individual factors (gender, age, education level, orientation, and age identification orientation) perceived family support with ISS; (2) associations ISS mood problems moderating effects gender on among Taiwanese young adult lesbian, gay, bisexual (LGB) individuals. In total, 500 male female LGB individuals aged between 20...

10.3390/ijerph19042427 article EN International Journal of Environmental Research and Public Health 2022-02-19

Poor sleep has been associated with diseases including cardiovascular, obesity and mental disorders. However, there is limited information on the correlation between duration quality peptic ulcer disease (PUD). This study aimed to investigate impact of incidence PUD in a large Taiwanese population follow-up study. The participants were recruited from Taiwan Biobank. Sleep duration, quality, presence assessed using self-reported questionnaires. categorized into three groups based duration: <...

10.7150/ijms.103639 article EN cc-by-nc International Journal of Medical Sciences 2025-01-21

Abstract Background Increased alcohol and sedatives/hypnotics use are prevalent among lesbian, gay bisexual (LGB) individuals, but very few prospective studies have examined the predictors of increased in LGB individuals. The aims this 4-year follow-up study were to examine predictive effects demographics, sexual stigma, self-identity confusion, anxiety, depression, perceived family function before COVID-19 pandemic on a group young adult individuals experiencing Taiwan. Methods data stigma...

10.1093/ijnp/pyae059.224 article EN cc-by-nc The International Journal of Neuropsychopharmacology 2025-02-01

Suicide is a major concern in public health worldwide. Early identification of individuals at risk critical for suicide prevention. The present study revised the 5-item Brief Symptom Rating Scale (BSRS-5) to checklist format (BSRS-5R) and validated BSRS-5R into screening tool psychiatric morbidity ideation general public. participants consisted two subsets sample from community residents patients. subjects were recruited stratified proportional randomization sampling nationwide survey, while...

10.1016/j.jfma.2015.05.004 article EN cc-by-nc-nd Journal of the Formosan Medical Association 2015-07-03

Abstract Research indicates smoking increases the risk of various kidney diseases, although developing stone disease in non-smokers exposed to secondhand smoke is unknown. This study analyzed a total 19,430 never-smokers with no history who participated Taiwan Biobank from 2008 2019. They were divided into two groups by exposure; exposure and groups; mean age participants was 51 years, 81% women. Incident development observed 352 (2.0%) 50 (3.3%) during follow-up 47 months. The odds ratio...

10.1038/s41598-021-97254-y article EN cc-by Scientific Reports 2021-09-06

In this paper, we aimed to examine the protective role of hyperuricemia in prevalence osteoporosis a large Asian cohort. A total 119,037 participants from 29 recruitment centers Taiwan were enrolled onto our study. Participants with serum uric acid greater than 7.0 mg/dL men and 6.0 women classified as group whereas others control group. The mean age all was 50; there 23,114 subjects (19%) hyperuricemia. Osteoporosis observed 8243 (9%) 1871 (8%) groups, respectively. After adjusting for...

10.3390/nu14112206 article EN Nutrients 2022-05-26

Depression is a common psychiatric health issue affecting an estimated 5% of adults worldwide, and it can lead to disability increased economic burden. Consequently, identifying the factors associated with depression as early possible vital issue. The aim this study was explore these associations in large cohort 121,601 Taiwanese participants Taiwan Biobank, also identify sex differences associations.The included 77,902 women 43,699 men (mean age, 49.9 ± 11.0 years), who were further...

10.3389/fpubh.2023.1070827 article EN cc-by Frontiers in Public Health 2023-03-16

The purpose of this study was to investigate genetic factors associated with metabolic syndrome (MetS) by conducting a large-scale genome-wide association (GWAS) in Taiwan, addressing the limited data on Asian populations compared Western populations. Using from Taiwan Biobank, comprehensive clinical and information 107,230 Taiwanese individuals analyzed. Genotyping TWB1.0 TWB2.0 chips, including over 650,000 single nucleotide polymorphisms (SNPs), were utilized. Genotype imputation using...

10.3390/nu16010077 article EN Nutrients 2023-12-25

Background Living alone has been linked to poor mental health, however large-scale epidemiological studies on the association between living and psychiatric morbidity including depression anxiety are lacking. The aim of this study was investigate issue in a large Taiwanese cohort. Methods In cross-sectional study, we enrolled 121,601 volunteers from 29 community recruitment stations Taiwan divided them into two groups based whether or not they lived alone. Psychiatric defined as Generalized...

10.3389/fpubh.2022.1054615 article EN cc-by Frontiers in Public Health 2022-11-17

We aim to explore the association between chronic kidney disease (CKD) and cataracts.A total of 121,380 participants with adequate information collected from 29 community-based recruitment centers since 2008 were analyzed. The CKD self-reported diagnosed cataracts was examined in a cross-sectional cohort validated longitudinal 25,263 without at baseline.Of all participants, occurred 503/1,947 (26%) 10,464/119,433 (9%) subjects non-CKD groups, respectively. Multivariate logistic regression...

10.3389/fpubh.2022.1029962 article EN cc-by Frontiers in Public Health 2022-12-07

Abstract Background Tobacco use and secondhand smoke (SHS) are risk factors of kidney stone disease (KSD). The hypothesis is that tobacco produces chemicals increase oxidative stress vasopressin, which leads to decreased urine output, contributes formation. aim this study was examine the effects smoking SHS on development KSD. Materials methods We analyzed a total 25,256 volunteers with no history KSD participated in Taiwan Biobank. presence underlying follow-up surveyed by...

10.1186/s12889-023-16116-6 article EN cc-by BMC Public Health 2023-06-20

Abstract Obesity has become a major public health issue which relate to numerous physical problems and highly comorbid with depression anxiety. Recently, some studies of technology-based interventions for weight reduction emerged overcome the barriers from time, cost distance. Mood component eating behavior related obesity are less discussed so far intervention though. This pilot study was aimed investigate effect telehealth assisted on reduction, mood status, change under smartphone...

10.1038/s41598-023-33238-4 article EN cc-by Scientific Reports 2023-04-20

Regular exercise can regulate bone maintenance and improve health. However, large-scale epidemiological studies on the association between regular incident osteoporosis in menopausal women are still lacking. We aimed to examine relationship risk of women. In cross-sectional analysis, we enrolled 30,046 postmenopausal with available information from database Taiwan Biobank. divided them into two groups according status exercise, no groups. A T-score -2.5 or more standard deviations below that...

10.3389/fpubh.2022.897363 article EN cc-by Frontiers in Public Health 2022-06-15

Background: The Mild Behavioral Impairment Checklist (MBI-C) has been developed to assess mild behavioral impairment (MBI). However, no study validated the use of MBI-C using a promising translation method in Taiwan. Thus, consistency and discrepancy between informant-rated self-rated scores have not extensively researched. Objective: This compared informant- versions among community-dwelling people Method: We recruited 202 pairs individuals without dementia aged ≥50 years their cohabitating...

10.3233/jad-220006 article EN Journal of Alzheimer s Disease 2022-10-07

Abstract The aims of this cross‐sectional study were to examine the associations between body weight and mental health indicators including depression, social phobia, insomnia, self‐esteem among Taiwanese adolescents in Grades 7–12. mass index (BMI) 5254 was calculated based on self‐reported height measurements. Body status determined by age‐ gender‐specific International Obesity Task Force reference tables. By using participants average as group, association (underweight, overweight,...

10.1016/j.kjms.2014.09.005 article EN publisher-specific-oa The Kaohsiung Journal of Medical Sciences 2014-10-24

Background Menopause is associated with an increased risk of kidney stone disease (KSD). However, for postmenopausal women, how to avoid KSD has rarely been studied. The aim this study was explore whether drinking tea a reduction in the prevalence women. Methods We collected 11,484 women from Taiwan Biobank, and used questionnaires obtain information on drinking, KSD, comorbidities. participants were divided into two groups according habitual consumption: tea-drinking non-tea-drinking...

10.7717/peerj.18639 article EN cc-by PeerJ 2024-12-11

(1) Background: Betel nut chewing injures bodily health. Although, the relationship between betel and kidney stone disease (KSD) is unknown. (2) Methods: We analyzed 43,636 men from Taiwan Biobank. divided them into two groups on status of chewing, never-chewer ever-chewer groups. Self-reported diagnosed KSD was defined as subject’s medical history in questionnaire. Logistic regression used to analyze association risk KSD. (3) Results: The mean age subjects present study 50 years, 16% were...

10.3390/jpm12020126 article EN Journal of Personalized Medicine 2022-01-18
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