A5048998034- Urological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Hormonal and reproductive studies
- Liver Disease Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Eosinophilic Esophagitis
- Genital Health and Disease
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Oral Health Pathology and Treatment
- Urinary and Genital Oncology Studies
- Cancer-related molecular mechanisms research
- Pelvic floor disorders treatments
- Alcohol Consumption and Health Effects
- Sexual function and dysfunction studies
- Female Genital Mutilation/Cutting Issues
- Prostate Cancer Diagnosis and Treatment
- Connexins and lens biology
- Urologic and reproductive health conditions
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Gout, Hyperuricemia, Uric Acid
- Bladder and Urothelial Cancer Treatments
- Cancer, Lipids, and Metabolism
Kaohsiung Medical University
2015-2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2015-2025
Kaohsiung Municipal Hsiao-Kang Hospital
2016-2025
Brigham and Women's Hospital
2022
Harvard University
2022
National Taiwan University Hospital
2012
California State University, Sacramento
2007
University of California Davis Medical Center
2005
Abstract This study investigates the correlation between body mass index (BMI) and osteoporosis utilizing data from Taiwan Biobank. Initially, a comprehensive analysis of 119,009 participants enrolled 2008 to 2019 was conducted assess association BMI prevalence. Subsequently, longitudinal cohort 24,507 participants, initially free osteoporosis, underwent regular follow-ups every 2–4 years analyze risk development, which subset main cohort. Participants were categorized into four groups:...
We aimed to examine the association between metabolic syndrome and risk of kidney stone development in a large-scale community-based cohort. A total 121,579 participants enrolled Taiwan Biobank were analyzed. They divided into two groups on basis presence syndrome. The disease was defined by self-reported history stones. mean age 50 years old, stones observed 3446 (10%) 4292 (5%) with without syndrome, respectively. Higher prevalence found compared those (odds ratio (OR), 1.32; 95%...
The prevalence and incidence rates of kidney stone disease (KSD) in Taiwan are high; however, the association between lipid profile KSD has yet to be investigated. aim this longitudinal study was investigate with baseline incident a large Taiwanese cohort. A total 27,002 people enrolled Biobank (TWB) were followed for median 4 years classified into two groups according whether they had (n = 1813; 6.7%) or did not have 25,189; 93.3%) at baseline. presence defined self-reported history stones....
Abstract Smoking is the most important risk factor for chronic obstructive pulmonary disease (COPD), however evidence from large-scale studies on whether secondhand smoke (SHS) increases of COPD still lacking. We conducted this large longitudinal study to investigate association between SHS and development COPD. This a study. Data 6519 subjects who were never-smokers, had no history COPD, complete lung function records extracted Taiwan Biobank. They divided into two groups according...
(1) Background: We aimed to explore the associations between menopause, postmenopausal hormone therapy, and metabolic syndrome in a large community-based group of Asian women. (2) Methods: This is cross-sectional study which we enrolled women aged 30 70 years with sufficient information about menopausal status from Taiwan Biobank. The definition for used this aligns Bureau Health Promotion’s (Taiwan) proposed definition. (3) Results: A total 17,460 were recruited. had higher prevalence (30%...
Abstract Background Gastroesophageal reflux disease (GERD) is a common global health issue. Previous studies have revealed higher prevalence of GERD in females than males, however few investigated sex differences the risk factors associated with GERD. Therefore, aim this population-based study was to examine for large cohort over 120,000 Taiwanese participants. Methods We enrolled 121,583 participants (male: 43,698; female: 77,885; mean age 49.9 ± 11.0 years) from Taiwan Biobank. The...
In this paper, we aimed to examine the protective role of hyperuricemia in prevalence osteoporosis a large Asian cohort. A total 119,037 participants from 29 recruitment centers Taiwan were enrolled onto our study. Participants with serum uric acid greater than 7.0 mg/dL men and 6.0 women classified as group whereas others control group. The mean age all was 50; there 23,114 subjects (19%) hyperuricemia. Osteoporosis observed 8243 (9%) 1871 (8%) groups, respectively. After adjusting for...
Poor sleep has been associated with diseases including cardiovascular, obesity and mental disorders. However, there is limited information on the correlation between duration quality peptic ulcer disease (PUD). This study aimed to investigate impact of incidence PUD in a large Taiwanese population follow-up study. The participants were recruited from Taiwan Biobank. Sleep duration, quality, presence assessed using self-reported questionnaires. categorized into three groups based duration: <...
Gastroesophageal reflux disease (GERD) and metabolic syndrome (MetS) have emerged as prominent health issues in past decades. This study aimed to evaluate whether the presence of MetS its constituent factors was associated with a higher likelihood GERD large cohort Taiwanese adults. components were defined according modified National Cholesterol Education Program Expert Panel Adult Treatment III for Asians, assessed using standardized interviews questionnaires. Of 121,583 participants from...
Managing patients with chronic pelvic pain syndrome (CPPS) refractory to the traditional 3-As therapy (antibiotics, alpha-blockers, and anti-inflammatories) is a challenging task. Low-intensity extracorporeal shock wave (LI-ESWT) was recently reported be able improve pain, urinary symptoms, even sexual function by inducing neovascularization anti-inflammation, reducing muscle tone, influencing nerve impulses. This study evaluates whether combined treatment LI-ESWT can restore clinical...
Abstract Research indicates smoking increases the risk of various kidney diseases, although developing stone disease in non-smokers exposed to secondhand smoke is unknown. This study analyzed a total 19,430 never-smokers with no history who participated Taiwan Biobank from 2008 2019. They were divided into two groups by exposure; exposure and groups; mean age participants was 51 years, 81% women. Incident development observed 352 (2.0%) 50 (3.3%) during follow-up 47 months. The odds ratio...
Metabolic syndrome (MetS) is prevalent in Taiwan; however, the association between MetS and cognitive function unclear. The aim of this study was to explore associations MetS, its components, obesity-related indices with a large Taiwanese cohort. We enrolled total 28,486 participants who completed Mini-Mental State Examination (MMSE) questionnaire, which used evaluate function. defined according NCEP-ATP III guidelines modified criteria for Asians. Ten were also evaluated: body mass index...
The purpose of this study was to investigate genetic factors associated with metabolic syndrome (MetS) by conducting a large-scale genome-wide association (GWAS) in Taiwan, addressing the limited data on Asian populations compared Western populations. Using from Taiwan Biobank, comprehensive clinical and information 107,230 Taiwanese individuals analyzed. Genotyping TWB1.0 TWB2.0 chips, including over 650,000 single nucleotide polymorphisms (SNPs), were utilized. Genotype imputation using...
Introduction: Gastroesophageal reflux disease (GERD) and peptic ulcer (PUD) are prevalent in Taiwan. Few studies have investigated the associations between obesity indices with GERD PUD simultaneously. This study aimed to investigate correlations among a large cohort of participants, around 120,000, Taiwan Biobank (TWB). Methods: A total 121,583 participants (male: 43,698; female: 77,885; mean age 49.9 ± 11.0 years) were included analyze indices, including body mass index (BMI), waist-hip...
DNA damage repair is frequently dysregulated in advanced prostate cancer and has been linked to susceptibility survival outcomes. The aim of this study assess the influence genetic variants pathways on prognosis cancer. Specifically, 167 single nucleotide polymorphisms (SNPs) 18 pathway genes were assessed for association with cancer-specific (CSS), overall (OS), progression-free (PFS) a cohort 630 patients receiving androgen deprivation therapy. Univariate analysis identified four SNPs...
Depression is a common psychiatric health issue affecting an estimated 5% of adults worldwide, and it can lead to disability increased economic burden. Consequently, identifying the factors associated with depression as early possible vital issue. The aim this study was explore these associations in large cohort 121,601 Taiwanese participants Taiwan Biobank, also identify sex differences associations.The included 77,902 women 43,699 men (mean age, 49.9 ± 11.0 years), who were further...
Abstract Background Tobacco use and secondhand smoke (SHS) are risk factors of kidney stone disease (KSD). The hypothesis is that tobacco produces chemicals increase oxidative stress vasopressin, which leads to decreased urine output, contributes formation. aim this study was examine the effects smoking SHS on development KSD. Materials methods We analyzed a total 25,256 volunteers with no history KSD participated in Taiwan Biobank. presence underlying follow-up surveyed by...
Abstract Background The 8th American Joint Committee on Cancer tumor–node–metastasis (AJCC‐TNM) staging system is based a few retrospective single‐center studies. We aimed to test the prognostic validity of and determine whether modified clinicopathological tumor that includes lymphovascular embolization could increase accuracy prediction for patients with stage T2–3 penile cancer. Methods A training cohort 411 who were treated at 2 centers in China Brazil between 2000 2015 staged according...
Background Living alone has been linked to poor mental health, however large-scale epidemiological studies on the association between living and psychiatric morbidity including depression anxiety are lacking. The aim of this study was investigate issue in a large Taiwanese cohort. Methods In cross-sectional study, we enrolled 121,601 volunteers from 29 community recruitment stations Taiwan divided them into two groups based whether or not they lived alone. Psychiatric defined as Generalized...
The prevalence rates of hepatitis B and C virus (HBV/HCV) infection are high in Taiwan, both common causes chronic liver disease its related complications. Therefore, the early detection factors associated with HBV/HCV is important. aim this study was to explore these a large cohort Taiwanese participants Taiwan Biobank, also identify sex differences risk factors.It an observational study. enrolled 121,421 participants, divided into four groups according presence or absence HBV HCV...
We aim to explore the association between chronic kidney disease (CKD) and cataracts.A total of 121,380 participants with adequate information collected from 29 community-based recruitment centers since 2008 were analyzed. The CKD self-reported diagnosed cataracts was examined in a cross-sectional cohort validated longitudinal 25,263 without at baseline.Of all participants, occurred 503/1,947 (26%) 10,464/119,433 (9%) subjects non-CKD groups, respectively. Multivariate logistic regression...
The global pandemic of obesity and the increasing incidence chronic respiratory diseases are growing health concerns. association between pulmonary function is uncertain. Therefore, this study aimed to explore associations changes in lung obesity-related indices a large longitudinal study. A total 9059 participants with no personal histories asthma, smoking, bronchitis, or emphysema were enrolled from Taiwan Biobank followed for 4 years. Lung was assessed using spirometry measurements...