A5071891562- Nanoparticle-Based Drug Delivery
- Pancreatic function and diabetes
- RNA Interference and Gene Delivery
- Electrospun Nanofibers in Biomedical Applications
- Graphene and Nanomaterials Applications
- Diabetes Management and Research
- Diabetes and associated disorders
- Advanced biosensing and bioanalysis techniques
- Nanoparticles: synthesis and applications
- CAR-T cell therapy research
- Hydrogels: synthesis, properties, applications
- Immune Cell Function and Interaction
- Bone Tissue Engineering Materials
- Nanoplatforms for cancer theranostics
- 3D Printing in Biomedical Research
- Immunotherapy and Immune Responses
- Advanced Drug Delivery Systems
- X-ray Diffraction in Crystallography
- Protein Degradation and Inhibitors
- Crystallization and Solubility Studies
- Advanced Nanomaterials in Catalysis
- Cancer Immunotherapy and Biomarkers
- Synthesis and biological activity
- Biosensors and Analytical Detection
- Nanocluster Synthesis and Applications
Kermanshah University of Medical Sciences
2019-2025
Royan Institute
2018-2020
Academic Center for Education, Culture and Research
2018-2020
Tehran University of Medical Sciences
2017-2018
Abstract Cancer is one of the most common diseases and causes death worldwide. Since treatment approaches do not yield acceptable results in many patients, developing innovative strategies for effective necessary. Immunotherapy promising that has been highly regarded preventing tumor recurrence new metastases. Meanwhile, inhibiting immune checkpoints attractive methods cancer immunotherapy. Cytotoxic T lymphocyte-associated protein-4 (CTLA-4) an essential molecule plays a vital role cell...
Abstract Background Interactive dressings are innovatively designed to interact with the wound surface and alter environment promote healing. In current study, we integrated physicochemical properties of Poly (caprolactone)/ (vinyl alcohol)/Collagen (PCL/PVA/Col) nanofibers biological activities Momordica charantia pulp extract develop an efficient dressing. The electrospinning method was applied fabricate nanofibers, prepared were thoroughly characterized. Results SEM imaging showed that...
Despite many advances in cancer treatment, still remains a major global health problem owing to its high rate of recurrence, the tendency metastasize, and development drug resistance. In addition animal models, researchers can employ vitro tumor models mimic vivo microenvironment with purpose discovering new therapeutic approaches. order engineer realistic that recapitulate not only progression but also angiogenesis metastasis, complex interacting factors must be taken into account....
Diabetes mellitus remains a pervasive global health concern, urging deeper exploration of islet transplantation as potential enduring solution. The efficacy this therapeutic approach pivots on the precision cryopreservation techniques, ensuring both viability and accessibility pancreatic islets. This study delves into merits cryopreserving these islets using disaccharide trehalose, accompanied by an inventive strategy involving poly L proline (PLP) cell-penetrating peptide to overcome...
This scenario was designed to investigate the protein corona pattern on pillar-layer surface of a Cu-based metal-organic framework (MOF) in human plasma. The [Cu(L)(L/)].1.3DMA (MOF-1) {L = 4, 4/-bipyridine and L/ 5-aminoisophthalic acid}, synthesized through sonochemical irradiation approach as well characterized by various techniques like scanning electron microscopy, Fourier-transform infrared spectroscopy, X-ray powder diffraction single-crystal diffraction. space group determined be an...
Abstract The main aim of the current study was to fabricate bio‐ and electro‐active electrospun nanofibrous neural conduits for peripheral nerve regeneration. At first, polyaniline ‐co‐ polydopamine (PANI‐ co ‐PDA) random copolymer synthesized using a chemical oxidation polymerization method. blended with poly(vinyl alcohol) (PVA) used electrospinning afford conduits. characterization showed that fabricated nanofibers have diameter in range 500–600 nm, incorporation PANI PDA slightly reduced...
It is an undoubted fact that remarkable clinical outcomes have demonstrated by synergistic chemoradiotherapy (CRT) approach, in comparison to solitary radiation therapy (RT) or chemotherapy (CT). Therefore, a novel pH- and radiation-sensitive nanocomposite hydrogel, β-cyclodextrin-graft-poly(succinic ethyl methacrylate)/MnO2 nanoparticles (β-CD-g-PSEMA/MnO2 NPs), was designed developed through grafting 2-hydroxyethyl methacrylate (HEMA) onto functionalized β-CD atom transfer radical...