A5012076614- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Aortic aneurysm repair treatments
- Atomic and Subatomic Physics Research
- Liver Disease Diagnosis and Treatment
- Peripheral Artery Disease Management
- Nuclear Physics and Applications
- Diagnosis and Treatment of Venous Diseases
- X-ray Diffraction in Crystallography
- Hepatocellular Carcinoma Treatment and Prognosis
- Crystallization and Solubility Studies
- Luminescence Properties of Advanced Materials
- Aortic Disease and Treatment Approaches
- Venous Thromboembolism Diagnosis and Management
- Liver Disease and Transplantation
- Liver Diseases and Immunity
- Liver physiology and pathology
- Metastasis and carcinoma case studies
- Infectious Aortic and Vascular Conditions
- Vascular Procedures and Complications
- Nuclear materials and radiation effects
- Cardiac, Anesthesia and Surgical Outcomes
- Gastric Cancer Management and Outcomes
- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
Juntendo University
2025
The Institute of Statistical Mathematics
2023
Japan Synchrotron Radiation Research Institute
2023
Aichi Medical University
2013-2023
Kishiwada Tokushukai Hospital
2012-2021
Aichi Medical University Hospital
2010-2020
Seirei Social Welfare Community
2014-2018
Seirei Hamamatsu General Hospital
2014-2017
National Institute of Information and Communications Technology
2005-2017
Hitachi (Japan)
2005-2015
The nonenzymatic glycosylation (glycation) of Cu-Zn-superoxide dismutase led to gradual inactivation the enzyme (Arai, K. Iizuka, S., Tada, Y., Oikawa, K., and Taniguchi, N. (1987) Biochim. Biophys. Acta 924, 292-296). purified superoxide from human erythrocytes comprises both glycated nonglycated forms. was isolated by boronate affinity chromatography. Incubation with D-[6-3H]glucose in vitro resulted accumulation radioactivity protein, Schiff base adducts were trapped NaBH4. sites...
The dependence of the light output and decay times Ce-doped Gd/sub 2/SiO/sub 5/ on Ce concentration was measured. It is shown that almost constant time can be easily changed by changing concentration. concluded these properties make it possible to use GSO(Ce) scintillators as position-sensitive detectors.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Accumulating evidence indicates that menaquinone-4 (MK-4), a vitamin K(2) with four isoprene units, inhibits osteoclastogenesis in murine bone marrow culture, but the reason for this inhibition is not yet clear, especially human culture. To clarify inhibitory mechanism, we investigated differentiation of colony-forming-unit fibroblasts (CFU-Fs) and osteoclasts to learn whether enhancement CFU-Fs from progenitor cells might relate osteoclast formation. Human were grown alpha-minimal essential...
Objectives: Although lumbar spondylosis is a major cause of low back pain and disability in elderly people, few epidemiological studies have been performed. The prevalence radiographic was investigated large-scale population study the association with examined. Methods: From nationwide cohort (Research on Osteoarthritis Against Disability; ROAD), 2288 participants aged ⩾60 years (818 men 1470 women) living urban, mountainous coastal communities were analysed. severity at intervertebral...
The authors have developed a GSO depth of interaction detector. Three scintillators with different concentration Ce were chosen and stacked along direction optically coupled to photomultiplier tube (PMT) or position sensitive (PSPMT). Pulse shape, light output zero-cross time measured select proper combination Ce. Selecting 3 Ce, single GSO/PMT detector was fabricated for estimating the possibility this method. Using analysis, peaks correspond decay times obtained. Finally, GSO/PSPMT block...
The purpose of this prospective study was to elucidate the efficacy using contrast-enhanced ultrasound characterise focal hepatic lesions appearing non-hypervascular on CT in chronic liver diseases.The population included 22 patients with cirrhosis or hepatitis, who between them had 27 smaller than 20 mm (mean 13.9 ± 3.4) that appeared CT. Contrast-enhanced perflubutane microbubble agent (Sonazoid, 0.0075 ml kg(-1)) performed prior ultrasound-guided needle biopsy, and intensity analysis done...
Study Design. Retrospective cohort study. Objective. To evaluate the impact of concomitant severe hip or knee osteoarthritis (OA) on patient-reported outcome measures (PROMs) and global alignment in patients undergoing surgery for lumbar spinal stenosis (LSS). Summary Background Data. Hip OA frequently coexist with LSS, contributing to diagnostic therapeutic complexities. Limited evidence exists regarding lower extremity baseline postoperative outcomes LSS. Methods. A total 121 LSS who...
During the development of hippocampus, action GABA shifts from depolarizing to hyperpolarizing, and brain-derived neurotrophic factor (BDNF) has important roles in GABAergic transmission. We demonstrate that BDNF (20 ng ml-1) rapidly reversibly potentiates postsynaptic GABAA receptor-mediated currents (by 80.5 +/- 14.3 %, n = 10) hippocampal CA1 pyramidal neurons isolated postnatal day (P)6 rats, using nystatin-perforated patch-clamp recordings. This potentiation is caused by an elevation...
Abstract Background/Aims: The aim was to examine the efficacy of contrast‐enhanced ultrasound (US) with Sonazoid ™ demonstrate ultrasonically unrecognizable hypervascular hepatocellular carcinoma (HCC) and apply percutaneous US‐guided treatments. Methods: subjects this prospective study were 44 cirrhotic patients 55 lesions (12.7±4.5 mm) found by computed tomography but unrecognized non‐contrast US. Contrast‐enhanced US performed these hepatic after an intravenous injection (0.0075 ml/kg)....
Several LGSO samples with different Ce doping were studied in comparison to GSO crystal. The light output, non-proportionality of the response, energy resolution and intrinsic measured compared intensity afterglow recorded second range time. A high output 17000plusmn1700 ph/MeV a good 6.5plusmn0.2% for 662 keV gamma rays from Cs source obtained best sample, doped 1 mol% Ce. and, particularly varied concentration tested crystals not correlated their common characteristics. In contrast,...
OBJECTIVE. The aim of this study was to evaluate the effectiveness contrast-enhanced ultrasound with a perflubutane microbubble agent in assessment cellular differentiation hepatocellular carcinoma (HCC).
1. The effects of somatostatin (SS) on the low-voltage-activated and high-voltage-activated (HVA) Ca2+ channels in pyramidal neurons acutely dissociated from hippocampal CA1 region 2- to 3-wk-old rats were investigated a nystatin perforated-patch recording configuration under voltage-clamp conditions. 2. SS had no effect channel but did inhibit HVA concentration-, time-, voltage-dependent manner. 3. showed activation phase Ba2+ current (IBa) passing through channels, maximum inhibition was...
A new method for a four-stage depth of interaction (DOI) detector is proposed. The DOI constructed with two kinds Gd/sub 2/SiO/sub 5/:Ce (GSO) crystals doped different amounts Ce, 0.5 mol% and 1.5 mol%. amount Ce in GSO determines the scintillation decay time constant, it 60 ns 35 GSO. This difference led to introduction pulse-shape discrimination, which would distinguish between event data from respective GSOs sort them into groups. By independently applying Anger-type position arithmetic...
BaMgF(4) is a ferroelectric fluoride which shows very wide transparency range extending from 125 nm to 13 microm. The conjunction of these properties confers unique chance for optical applications in the UV and mid-IR wavelength regions, where other nonlinear materials cannot be used. In particular its application as frequency converter all solid-state lasers considered. dispersion refractive indices along three principal axes measured transparent region, Sellmeier coefficients are...