A5014890619- Air Quality and Health Impacts
- Environmental Toxicology and Ecotoxicology
- Immunotoxicology and immune responses
- Heavy Metal Exposure and Toxicity
- Smoking Behavior and Cessation
- Birth, Development, and Health
- Occupational Health and Performance
- Climate Change and Health Impacts
- Aquaculture disease management and microbiota
- Toxic Organic Pollutants Impact
- Animal testing and alternatives
- Vanadium and Halogenation Chemistry
- Environmental Justice and Health Disparities
- Noise Effects and Management
- Energy and Environment Impacts
- Heavy metals in environment
- Carcinogens and Genotoxicity Assessment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Effects and risks of endocrine disrupting chemicals
- Health, Environment, Cognitive Aging
- Inhalation and Respiratory Drug Delivery
- Asthma and respiratory diseases
- Adipose Tissue and Metabolism
- Cancer Risks and Factors
- Per- and polyfluoroalkyl substances research
New York University
2016-2025
Pocatello High School
2018
NYU Langone Health
1997-2017
Duke University
2003
Columbia University Irving Medical Center
1988-1998
University Medical Center
1996
National Center of Hygiene Medical Ecology and Nutrition
1995
University of Washington
1995
University of Rochester Medical Center
1995
Research Triangle Park Foundation
1994-1995
One industrially important metal oxide nanoparticle (NP) is cadmium (CdO). A study was performed using timed-pregnant CD-1 mice to determine if Cd associated with inhaled CdO NP could reach the placenta and adversely affect developing fetus and/or neonate. Pregnant were exposed by inhalation either every other day 100 μg of freshly generated CdO/m3 (exposure 1) or daily 230 2). In each exposure, carrier gas (control) for 2.5 h from 4.5 days post coitus (dpc) through 16.5 dpc. At 17.5 dpc,...
Electronic cigarettes (e-cigarettes), battery-powered devices containing nicotine, glycerin, propylene glycol, flavorings, and other substances, are increasing in popularity. They pose a potential threat to the developing brain, as nicotine is known neurotoxicant. We hypothesized that exposure e-cigarettes during early life stages induce changes central nervous system (CNS) transcriptome associated with adverse neurobiological outcomes long-term disease states. To test hypothesis, pregnant...
Journal Article Genetic toxicology of lead compounds Get access J. T. Zelikoff, Zelikoff Institute Environmental Medicine, New York University Medical Center550 First Avenue, York, NY 10016, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar H. Li, Li A. Hartwig, Hartwig X.W. Wang, Wang M. Costa, Costa G. Rossman 1 To whom correspondence should be addressed Carcinogenesis, Volume 9, Issue 10, October 1988, Pages 1727–1732,...
Increasing evidence indicates that the central nervous system (CNS) is a target of air pollution. We previously reported postnatal exposure mice to concentrated ambient ultrafine particles (UFP; ≤100 nm) via University Rochester HUCAPS during critical developmental window CNS development, equivalent human 3rd trimester, produced male-predominant neuropathological and behavioral characteristics common multiple neurodevelopmental disorders, including autism spectrum disorder (ASD), in humans....
U.S. adolescents increasingly use alternative tobacco products (ATPs), including hookah. No study has previously assessed correlates of adolescent hookah in a nationally representative sample. Cross-sectional, data from the 2011 National Youth Tobacco Survey (NYTS) were used. Student demographics and their of, exposure to, beliefs about examined as use. Of nationwide, 7.3% reported ever trying 2.6% using within past month. Increasing age was associated with hookah, but not current Sex...
Background: Epidemiological studies associate inhalation of fine-sized particulate matter (PM2.5) during pregnancy with preterm birth (PTB) and low weight (LBW) but disagree over which time frames are most sensitive, or if effects cumulative. Objectives: Our objective was to provide experimental plausibility for epidemiological observations by testing the hypothesis that exposure PM2.5 discrete periods results in PTB LBW. Methods: For first study, timed-pregnant B6C3F1 mice were exposed...
Cadmium oxide nanoparticles (CdO NPs) are employed in optoelectronic devices and as a starting material for generating quantum dots well medical imaging targeting of pharmaceutical agents to disease sites. However, there lack data concerning short- long-term effects CdO NPs on the lungs.To determine inhaled at an occupationally relevant concentration pulmonary injury repair, systemic immunity adult male mice.Mice were exposed 240 μg NPs/m(3) seven days (3 h/d) lavage levels...
Abstract Recent epidemiological data indicate that the popularity of electronic cigarettes (e-cigarettes), and consequently nicotine use, is rising in both adolescent adult populations. As a known developmental neurotoxin, these products present potential threat for those exposed during early life stages. Despite this, few studies have evaluated toxicity e-cigarettes on developing central nervous system. The goal this study was to assess neurotoxicity resulting from early-life exposure...
AbstractRespiratory-tract infection, specifically pneumonia, contributes substantially to the increased morbidity and mortality among elderly individuals exposed airborne particulate matter of <10 µm diameter (PM 10) . These epidemiological findings suggest that PM 10 may act as an immunosuppressive factor can undermine normal pulmonary antimicrobial defense mechanisms. To investigate whether, how, compromised immunocompetence might contribute mortality, two sets laboratory studies were...