A5019599463- Lung Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- AI in cancer detection
- Advanced X-ray and CT Imaging
- Cancer Immunotherapy and Biomarkers
- Cardiac tumors and thrombi
- Lung Cancer Research Studies
- Sarcoma Diagnosis and Treatment
- Radiation Dose and Imaging
- Myasthenia Gravis and Thymoma
- Occupational and environmental lung diseases
- Cancer Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Head and Neck Cancer Studies
- Vascular Tumors and Angiosarcomas
- Tracheal and airway disorders
- Pleural and Pulmonary Diseases
- Meningioma and schwannoma management
- Atomic and Subatomic Physics Research
- Colorectal Cancer Treatments and Studies
- Pneumocystis jirovecii pneumonia detection and treatment
Tokyo National Hospital
2012-2025
National Cancer Center Hospital East
2014-2024
National Cancer Center
2008-2024
National Cancer Centre Japan
2005-2024
University of Tokyo Hospital
2024
Osaka University
2024
Osaka University Hospital
2024
National Hospital Organization Kyushu Cancer Center
2006-2022
Niigata University
2020
The Cancer Institute Hospital
2019
PURPOSE: Because efficacy of lung cancer screening using chest x-ray is controversial and insufficient, other modalities need to be developed. To provide data on performance low-dose helical computed tomography (CT) scanning its in terms survival, a one-arm longitudinal project was conducted. PATIENTS AND METHODS: A total 1,611 asymptomatic patients aged 40 79 years, 86% with smoking history, were screened by CT scan, x-ray, 3-day pooled sputum cytology 6-month interval. RESULTS: At initial...
Keishi Kubo, Arata Azuma, Minoru Kanazawa, Hideto Kameda, Masahiko Kusumoto, Akihiko Genma, Yasuo Saijo, Fumikazu Sakai, Yukihiko Sugiyama, Koichiro Tatsumi, Makoto Dohi, Hitoshi Tokuda, Shu Hashimoto, Noboru Hattori, Masayuki Hanaoka, Yuh Fukuda, the Japanese Respiratory Society Committee for formulation of Consensus statement diagnosis and treatment drug-induced lung injuries Nagano Prefectural Hospital Organization, Japan Division Pulmonary Medicine, Infections Diseases, Oncology,...
Purpose The image noise and quality of a prototype ultra-high-resolution computed tomography (U-HRCT) scanner was evaluated compared with those conventional high-resolution CT (C-HRCT) scanners. Materials Methods This study approved by the institutional review board. A U-HRCT 0.25 mm x 4 rows operating at 120 mAs used. C-HRCT images were obtained using 0.5 16 or 64 detector-row 150 mAs. Images from both scanners reconstructed 0.1-mm intervals; slice thickness for For scanners, display field...
Purpose To clarify the percentage of solitary pure ground-glass nodules (SPGGNs) 5 mm or smaller that grow and develop into invasive adenocarcinomas. Materials Methods This study was approved by institutional review board, informed consent obtained from all people who were screened. From February 2004 through December 2007, 7294 participants underwent screening for lung cancer with computed tomographic (CT) imaging. The nodule database reviewed to identify SPGGNs smaller. Growth evaluated as...
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease implicated as an independent risk factor for cancer. However, optimal treatment advanced cancer with IPF remains to be established. We performed randomised phase 3 trial (J-SONIC) assess the efficacy and safety of nintedanib plus chemotherapy (experimental arm) compared alone (standard-of-care nonsmall cell (NSCLC) IPF.Chemotherapy-naïve NSCLC patients were allocated receive carboplatin (area under curve 6 on day 1) nanoparticle...
Objective: To clarify the progression of focal pure ground-glass opacity (pGGO) detected by low-dose helical computed tomography (CT) screening for lung cancer. Methods: A total 15,938 CT examinations were performed in 2052 participants project, and 1566 them judged to have yielded abnormal findings requiring further examination. Patients with peripheral nodules exhibiting pGGO at time first thin-section examination confirmed histologically after follow-up more than 6 months enrolled current...
Interstitial lung disease (ILD) occurrence and risk factors were investigated in the Japanese non-small-cell cancer, post-marketing, large-scale surveillance study, POLARSTAR. All patients with unresectable, recurrent/advanced cancer who treated erlotinib Japan between December 2007 October 2009 enrolled. Primary endpoints patterns of ILD for onset ILD-related death. Overall survival, progression-free adverse drug reactions secondary endpoints. was confirmed 429 (4.3%) patients....
This was an observational study of Japanese participants who underwent low-dose computed tomographic (LDCT) lung cancer screening between February 2004 and March 2012, to evaluate the cancers in never-smokers smokers.The population consisted a total 12,114 subjects [never-smokers, 6,021 (49.70%); smokers with <30 pack-years smoking, 3,785 (31.24%); ≥30 2,305 (19.03%); unknown smoking status, 3 (0.02%)]. The odds ratio (OR) detection according status adjusted for age gender evaluated.A 152...
The purpose of this work was to evaluate the CT features thymoma and determine most helpful findings in differentiating invasive from noninvasive thymoma.The scans 27 patients with 23 were independently assessed by two observers without knowledge their invasiveness. presence distribution various analyzed.Invasive thymomas more likely have lobulated (16/27, 59%) or irregular (6/27, 22%) contours than (8/23, 35% 1.5/23, 6%, respectively) (p < 0.05). Invasive had a higher prevalence low...
We sought to assess the CT features of surgically resected large cell neuroendocrine carcinoma lung.The cases all patients who underwent surgical resection for primary lung cancer in a single institution from 1993 2000 and received an initial diagnosis poorly differentiated non-small carcinoma, small carcinoid tumor, were histologically reviewed. The findings 43 reclassified confirmed as carcinoma. scans available 38 evaluated by two observers.In patients, six central tumors 32 peripheral...
Abstract Purpose: Epidermal growth factor receptor (EGFR) mutations, especially in-frame deletions in exon 19 (DEL) and a point mutation 21 (L858R), predict gefitinib sensitivity patients with non–small cell lung cancer (NSCLC). In this study, we verified the accuracy of EGFR analysis small samples by high-resolution melting (HRMA), which is rapid method using PCR amplification dye to analyze curves NSCLC. Experimental Design: We designed prospective study compare specificity HRMA DNA...
There is no existing worldwide published method for mediastinum compartment classification based on transverse section images the differential diagnosis of mediastinal tumors. Herein, we describe a new anatomic using computed tomography (CT) and use this to classify lesions, thus evaluate whether sufficiently user-friendly useful. In publication Japanese Association Research Thymus (JART), proposed following four compartments CT images: superior portion mediastinum, anterior (prevascular...
<h3>BACKGROUND AND PURPOSE:</h3> Dual-energy CT can distinguish iodine-enhanced tumors from nonossified cartilage and has been investigated for evaluating invasion in patients with laryngeal hypopharyngeal squamous cell carcinomas. In this study, we compared the diagnostic accuracy of MR imaging a combination weighted-average iodine overlay dual-energy images detecting by carcinomas, particular thyroid invasion. <h3>MATERIALS METHODS:</h3> Fifty-five consecutive who underwent 3T 128-slice...