- Venous Thromboembolism Diagnosis and Management
- Diagnosis and Treatment of Venous Diseases
- Infective Endocarditis Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Antimicrobial Resistance in Staphylococcus
- Infectious Aortic and Vascular Conditions
- Advanced MRI Techniques and Applications
- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Vascular Procedures and Complications
- Bacterial biofilms and quorum sensing
- Streptococcal Infections and Treatments
- Vibrio bacteria research studies
- Salmonella and Campylobacter epidemiology
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Infections and bacterial resistance
- Bone and Dental Protein Studies
- Medical Imaging and Pathology Studies
- Plant Pathogenic Bacteria Studies
- Electrical and Bioimpedance Tomography
- Vitamin C and Antioxidants Research
- Advanced X-ray and CT Imaging
- Hedgehog Signaling Pathway Studies
- Body Composition Measurement Techniques
Chiayi Chang Gung Memorial Hospital
2018-2024
National Yang Ming Chiao Tung University
2020-2024
Chang Gung University
2018-2023
Barking, Havering And Redbridge University Hospitals NHS Trust
2015-2021
Queen's Hospital
2021
Chang Gung Memorial Hospital
2021
National Cheng Kung University
2021
Chang Gung Children's Hospital
2019
Russells Hall Hospital
2015
King's College Hospital
2006
Introduction Staphylococcus aureus , is a pathogen commonly encountered in both community and hospital settings. Patients receiving hemodialysis treatment face an elevated risk of vascular access infections (VAIs) particularly infection. This heightened attributed to the characteristics enabling it adhere suitable surfaces form biofilms, thereby rendering resistant external interventions complicating efforts. Methods Therefore this study utilized PCR microtiter dish biofilm formation assay...
Burkholderia is an important bacterial genus containing several species of ecological, biotechnological and pathological interest. Bacterial isolate can be gotten from soil, water, plants even clinics. With their taxonomy undergoing constant revision the phenotypic similarity species, correct identification difficult. cepacia complex (Bcc) consists nine discrete genomic a genetic scheme based on recA gene has greatly enhanced B. species. The objectives this study were to identify strain UPM...
Venous diseases in the lower extremities long lacked an objective diagnostic tool prior to advent of triggered angiography non-contrast-enhanced (TRANCE) technique.An observational study with retrospective data analysis.Between April 2017 and June 2019, 66 patients were evaluated for venous through TRANCE-magnetic resonance imaging (MRI) grouped according whether they had occlusive (OV) disease, a static ulcer (SU), or symptomatic varicose veins (VV). The clinical appliance TRANCE-MRI was...
Escherichia coli is one major cause of bacterial infections and can horizontally acquire antimicrobial resistance virulence genes through conjugation. Because conjugative plasmids rapidly spread among bacteria different species, the carrying both may pose a significant threat to public health. Therefore, identification characterization these facilitate better understanding E. pathogenesis development new strategies against infections. iron uptake ability potential trait bacteria, we screened...
Metal oxide nanoparticles with photothermal properties have attracted considerable research attention for their use in biomedical applications. Cesium tungsten (Cs
To explore the diagnostic performance of 4-dimensional phase-contrast magnetic resonance imaging (4D PC-MRI) in evaluating aortic dissection different clinical scenarios.The study group comprised 32 patients with a known who each underwent computed tomography angiography (CTA), and then 4D PC-MRI 1.5-T MR scanner. The images were compared CTA to evaluate size, branch identification, iliac femoral arterial access.The divided into three groups: (I) diagnosed Type B but did not undergo...
Objectives: The distribution of venous pathology in stasis leg ulcers is unclear. main reason for this uncertainty the lack objective diagnostic tools. To fill gap, we assessed effectiveness triggered angiography non-contrast-enhanced (TRANCE)-magnetic resonance imaging (MRI) determining status patients with ulcers. Methods: This prospective observational study included data 23 who underwent TRANCE-MRI between April 2017 and May 2020; were retrospectively analyzed. TRANCE MRI utilizes...
Burkholderia cepacia complex (BCC) is a group of closely related bacteria with widespread environmental distribution. BCC are opportunistic pathogens that cause nosocomial infections in patients, especially cystic fibrosis (CF). Multilocus sequence typing (MLST) used nowadays to differentiate species within the complex. This study collected 41 isolates from vascular access (VAIs) and other clinical between 2014 2020. We preliminarily identified bacterial using standard biochemical procedures...
Objectives: To find an objective diagnostic tool for the superficial veins in legs. Methods: This study included 137 patients who underwent TRANCE-MRI from 2017 to 2020 (IRB: 202001570B0). Among them, 53 with unilateral leg venous diseases a QFlow scan and were classified into reflux non-reflux groups according status of great saphenous veins. Results: The QFlow, namely stroke volume (SV), forward flow (FFV), mean flux (MF), distance (SD), velocity (MV) measured external iliac, femoral,...
A 19-week-old, entire female boxer dog was presented for evaluation of chronic, progressive multi-focal neurological signs. Magnetic resonance imaging suggested a large intra-axial mass in the brainstem. Euthanasia performed and an anaplastic astrocytoma found at post-mortem examination. This case reports unusual naturally occurring brain tumour young dog.
Abstract Hemodialysis patients are particularly vulnerable to Staphylococcus aureus infection, with the vascular access serving as site of entry for this formidable pathogen. Patients arteriovenous grafts (AVGs) and tunneled‐cuffed catheters (TCCs) at elevated risk S. infection. In study, we investigated correlation between clinical characteristics infection (VAI), molecular profiles, biofilm formation abilities isolates . We collected samples methicillin‐resistant (MRSA),...
(1) Background: To assess the effectiveness of triggered angiography non-contrast-enhanced (TRANCE)-magnetic resonance imaging (MRI) in superficial venous reflux and its difference from health controls. (2) Methods: Thirty patients underwent TRANCE MRI before surgical intervention their legs. Ten healthy volunteers were included as a control. (3) Results: involves major tributaries, thus enhances additional ablations 20% patients. QFlow pattern (QFlow GSV/PV MF ratio > 1) was compared...
To investigate the rate of asymptomatic recurrence stage 1 endometrioid endometrial cancer and assess role routine hospital follow-up after treatment.We performed a retrospective case-note review study women who were diagnosed with adenocarcinoma at Queen's Hospital, Romford, between January 2008 December 2016.We included 299 patients median period 44.4 months. All underwent total hysterectomy bilateral salpingo-oophorectomy. Adjuvant radiotherapy was offered to subsequent discussions in...
Abstract Since venous reflux is difficult to quantify, triggered angiography non-contrast-enhanced (TRANCE)-magnetic resonance imaging (MRI) a novel tool for objectively evaluating diseases in the lower extremities without using contrast media. This study included 26 pre-intervention patients with superficial and 15 healthy volunteers. The quantitative flow (QFlow) analyzed phase shift information from pixels within region of interest MRI. fast simple radial basis function neural network...
Imaging characteristics of stasis leg ulcers (SLUs) are not easily demonstrated through existing diagnostic tools. Early diagnosis and treatment crucial. This pilot study was conducted to assess the quantitative flow (QFlow) in triggered angiography noncontrast enhanced (TRANCE) magnetic resonance imaging (MRI) identify hemodynamics victims with (SLUs). included 33 patients SLUs 14 healthy controls (HC). The were divided into a reflux (15 patients) nonreflux group (18 patients). QFlow done...
Abstract Hemodialysis requires repeated, reliable access to the systemic circulation; therefore, a well‐functioning vascular (VA) procedure is crucial for stable hemodialysis. VA infections (VAIs) constitute most challenging complication and cause considerable morbidity, loss of access, even death. In this study, we investigated molecular profiles different bacterial isolates retrieved from various types grafts. We collected clinical hemodialysis patients with VAIs in our institution period...
Background and Objectives: Compression of the common iliac veins (CIV) is not always associated with lower extremity symptoms. This study analyzed this issue from perspective patient venous blood flow changes using quantitative magnetic resonance imaging. Materials Methods: After we excluded patients active deep vein thrombosis, mean flux (MF) velocity (MV) popliteal vein, femoral external (EIV) were compared between left right sides. Results: Overall, 26 had unilateral CIV compression,...
Background: To examine the application of quantitative 2-dimensional phase-contrast MRI (2D PC-MRI) for treating patients with pelvic congestion syndrome (PCS). Materials and Methods: The authors conducted a retrospective cross-sectional analysis by using 2D PC-MRI data enrolled between April 2017 September 2023. In addition, 32 healthy female controls (HCs) were included. Results: Most PCS presented chronic pain more than half had extrapelvic venous symptoms (80/81, 98% 45/81, 56%,...
Salmonella infection is most common in patients with infected aortic aneurysm, especially Asia. When the wall heavily atherosclerotic, intima vulnerable to invasion by Salmonella, leading development of aneurysm. By using THP-1 macrophage-derived foam cells mimic atherosclerosis, we investigated role three enterica serotypes - Typhimurium, Enteritidis, and Choleraesuis cell autophagy inflammasome formation. Herein, provide possible pathogenesis Salmonella-associated aneurysms. Three S. or...
Background: Familial hypercholesterolaemia (FH) is associated with accelerated atherosclerosis. Diagnosis based on clinical scores and only 45% of those a diagnosis have genetic mutation known to be FH. Coronary artery calcium (CAC) scoring can used as surrogate marker for coronary disease, but data its use in FH are scarce.Methods: CAC was performed 52 asymptomatic patients (16 ‘probable FH’ 36 ‘possible FH’) classified according modified Simon Broome criteria, who were attending secondary...
Background: Familial hypercholesterolaemia (FH) is associated with accelerated atherosclerosis. Diagnosis based on clinical scores and only 45% of those a diagnosis have genetic mutation known to be FH. Coronary artery calcium (CAC) scoring can used as surrogate marker for coronary disease, but data its use in FH are scarce.Methods: CAC was performed 52 asymptomatic patients (16 'probable FH' 36 'possible FH') classified according modified Simon Broome criteria, who were attending secondary...
Patients receiving hemodialysis are at risk of vascular access infections (VAIs) and particularly vulnerable to the opportunistic pathogen Staphylococcus aureus. Hemodialysis patients were also increased infection during COVID-19 pandemic. Therefore, this study determined change in molecular antibiotic resistance profiles S. aureus isolates from VAIs pandemic compared with before. 102 collected between November 2013 December 2021. Before pandemic, 69 collected, 58%, 39.1%, 2.9% arteriovenous...
Background and Objectives: This study was conducted to investigate whether Pseudomonas aeruginosa (PA) infections of arteriovenous grafts (AVGs) recur more frequently than other bacterial following treatment with revision. Materials Methods: Operative procedures, including total excision, subtotal revision, were performed on 60 patients treat 65 AVG infections. Final outcomes classified as no infection recurrence, death without prior recurrence. In the competing risk setting, cumulative...
Staphylococcus aureus is a major human pathogen that produces various virulence factors which promote the binding of bacteria to tissues and medical devices such as vascular access devices, thereby developing wide range invasive infections. Vascular serves an entry site for S. elevates risk infection in hemodialysis population. Nevertheless, distribution genes spp. associated with infections (VAIs) has not been studied previously. In this study, we determined relationship between molecular...