- Cardiovascular and exercise physiology
- Sports Performance and Training
- Physical Activity and Health
- Muscle metabolism and nutrition
- Adipose Tissue and Metabolism
- Exercise and Physiological Responses
- Heart Rate Variability and Autonomic Control
- Hormonal and reproductive studies
- Genetics and Physical Performance
- Obesity, Physical Activity, Diet
- Nutrition and Health in Aging
- Muscle Physiology and Disorders
- Obesity and Health Practices
- Body Composition Measurement Techniques
- Mitochondrial Function and Pathology
- Muscle and Compartmental Disorders
- Cardiovascular Effects of Exercise
- Pharmacology and Obesity Treatment
- Health and Lifestyle Studies
- Sports injuries and prevention
- Diet and metabolism studies
- Vitamin D Research Studies
- Diversity and Impact of Dance
- Hemoglobin structure and function
- Nutrition, Genetics, and Disease
University of Stirling
2012-2024
Loughborough University
2019
University of Bath
2011-2019
University of Ulster
2017
Heriot-Watt University Malaysia
2011
Heriot-Watt University
2006-2010
Maastricht University Medical Centre
2010
Wenner-Gren Foundations
2009
Stockholm University
2009
University of Essex
2001-2006
Traditional high volume aerobic exercise training reduces cardiovascular and metabolic disease risk but involves a substantial time commitment. Extremely low high-intensity interval (HIT) has recently been demonstrated to produce improvements function, it is unknown whether HIT the capacity improve insulin action hence glycemic control.Sixteen young men (age: 21 +/- 2 y; BMI: 23.7 3.1 kg x m-2; VO2peak: 48 9 ml kg-1 min-1) performed weeks of supervised comprising total 15 min (6 sessions;...
A low maximal oxygen consumption (VO2max) is a strong risk factor for premature mortality. Supervised endurance exercise training increases VO2max with very wide range of effectiveness in humans. Discovering the DNA variants that contribute to this heterogeneity typically requires substantial sample sizes. In present study, we first use RNA expression profiling produce molecular classifier predicts response. We then hypothesized genes would harbor contributed heterogeneous Two independent...
The molecular pathways that are activated and contribute to physiological remodeling of skeletal muscle in response endurance exercise have not been fully characterized. We previously reported ∼800 gene transcripts regulated following 6 wk supervised training young sedentary males, referred as the training-responsive transcriptome (TRT) (Timmons JA et al. J Appl Physiol 108: 1487-1496, 2010). Here we utilized this database together with data on biological variation adaptation aerobic both...
It has not been established which physiological processes contribute to endurance training-related changes (Delta) in aerobic performance. For example, the relationship between intramuscular metabolic responses at intensity used during training and improved human functional capacity examined a longitudinal study. In present study we hypothesized that improvements (Vo(2max)) control would combine equally explain enhanced Twenty-four sedentary males (24 +/- 2 yr; 1.81 0.08 m; 76.6 11.3 kg)...
Over the past decade, it has been convincingly shown that regularly performing repeated brief supramaximal cycle sprints (sprint interval training [SIT]) is associated with aerobic adaptations and health benefits similar to or greater than moderate-intensity continuous (MICT). SIT often promoted as a time-efficient exercise strategy, but most commonly studied protocol (4-6 30-s Wingate 4 min recovery, here referred 'classic' SIT) takes up approximately 30 per session. Combined high perceived...
Regular physical activity (PA) can reduce the risk of developing type 2 diabetes, but adherence to time-orientated (150 min week-1 or more) PA guidelines is very poor. A practical and time-efficient regime that was equally efficacious at controlling factors for cardio-metabolic disease one solution this problem. Herein, we evaluate a new genuinely high-intensity interval training (HIT) protocol in men women with pre-existing diabetes.One hundred eighty-nine sedentary (n = 101) 88) impaired...
Reduced-exertion high-intensity interval training (REHIT) is a genuinely time-efficient intervention that can improve aerobic capacity and insulin sensitivity in sedentary individuals. The present study compared the effects of REHIT moderate-intensity walking on health markers patients with type 2 diabetes (T2D) counter-balanced crossover study. Sixteen men T2D (mean ± SD age: 55 5 years, body mass index: 30.6 2.8 kg·m-2, maximal capacity: 27 4 mL·kg-1·min-1) completed 8 weeks (three 10-min...
Previously it has been reported that reduced-exertion high-intensity interval training (REHIT; total time of 3 × 10 min per week) improves maximal aerobic capacity in both sedentary men and women, but insulin sensitivity only. The aim the present study was to determine whether there is a true sex difference response REHIT, or these findings can be explained by large interindividual variability inherent all exercise training. Thirty-five participants (18 women; mean ± SD age for respectively:...
The efficacy of high-intensity interval training (HIT) as a time-efficient exercise strategy for beneficially modifying risk factors cardiovascular disease has repeatedly been demonstrated in controlled laboratory settings. However, the effectiveness HIT an unsupervised workplace setting not investigated. objective this study was to use mixed methods investigate feasibility, acceptability and short-duration, intervention (REHIT) when applied setting.Twenty-five office-workers (mean ± SD age:...
In recent years, research investigating the dose-response to sprint interval training (SIT) has provided evidence that number and duration of repetitions in a SIT session can be reduced whilst preserving beneficial health-related adaptations. Together this led development protocols involving minimal doses SIT: regularly performing just two or three 20–30 s all-out sprints 10 min been shown elicit metabolic cardiovascular These protocols, which we originally termed “reduced-exertion...
VAN MARKEN LICHTENBELT, W. D., F. HARTGENS, N. B. J. VOLLAARD, S. EBBING, and H. KUIPERS. Body Composition Changes in Bodybuilders: A Method Comparison. Med. Sci. Sports Exerc., Vol. 36, No. 3, pp. 490–497, 2004. Introduction Few studies report on validation of body composition changes using the four-compartment model (4C), no such are available strength training. Here we present a study for determination fat fat-free mass bodybuilders, who used exercise androgenic-anabolic steroids. Methods...
This article reviews the role of free radicals in causing oxidative stress during exercise. High intensity exercise induces and although there is no evidence that this affects sporting performance short term, it may have longer term health consequences. The mechanisms exercise-induced are not well understood. Mitochondria sometimes considered to be main source radicals, but vitro studies suggest they play a more minor than was first thought. There growing acceptance importance haem proteins...
Recent studies have demonstrated that modifying the “classic” 6 × 30-s “all-out” sprint interval training protocol by incorporating either shorter sprints (6 10-s or 15-s sprints) fewer (e.g., 2 20-s sprints; reduced-exertion high-intensity (REHIT)) does not attenuate training-induced improvements in maximal aerobic capacity. The aim of present study was to determine if reducing duration REHIT from 20 s 10 per influences acute affective responses and change capacity following training....