Saira Shahnawaz

ORCID: 0000-0002-4580-0728
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Epigenetics and DNA Methylation
  • Birth, Development, and Health
  • Intramuscular injections and effects
  • Diabetes Treatment and Management
  • Maternal and fetal healthcare
  • Trauma and Emergency Care Studies
  • Cancer Risks and Factors
  • Pregnancy and Medication Impact
  • Nuclear Receptors and Signaling
  • Vitamin C and Antioxidants Research
  • Pancreatic function and diabetes
  • Metabolism, Diabetes, and Cancer
  • Chronic Kidney Disease and Diabetes
  • Diabetes and associated disorders
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Drug Transport and Resistance Mechanisms

University of Sargodha
1970-2024

University of Bern
2021-2023

Jinnah Medical & Dental College
2021-2022

Early miscarriage (EMC) is a devastating obstetrical complication. ATP-binding cassette (ABC) transporters mediate cholesterol transfer across the placenta and enhance cell survival by effluxing substrates from target cells in presence of stressors. Recent evidence reports an intricate interplay between autophagy ABC transporters. We hypothesized that dysregulated oxidative stress (OS) leads to abnormal expression membrane contributing poor pregnancy EMC. determined mRNA protein genes...

10.3390/antiox10111742 article EN cc-by Antioxidants 2021-10-30

The Developmental Origins of Health and Disease hypothesis sustains that exposure to different stressors during prenatal development prepares the offspring for challenges be encountered after birth. We studied gestational period as a particularly vulnerable window where can have strong implications fetal programming offspring's life-long metabolic status via alterations specific placentally expressed nutrient transporters. To study this mechanism, we used murine stress model, human...

10.1016/j.metabol.2024.155793 article EN cc-by Metabolism 2024-01-29

BACKGROUND: Diabetic kidney disease is a common and severe microvascular complication of diabetes mellitus (DM). There are limited data regarding alteration urine parameters other than proteinuria among DM patients.METHODS: Institution based cross-sectional study was conducted from February to May 2017 assess patients at the University Gondar Hospital, Northwest Ethiopia. A Systematic random sampling technique used recruit adult (≥18 years) diabetic participants. Data were collected after...

10.4314/ejhs.v29i1.9 article EN Ethiopian Journal of Health Sciences 1970-01-01

Objective: The purpose of this study is to evaluate the effectiveness vitamin D (cholecalciferol) injections against taken orally in treatment rickets children. Methodology: One hundred patients were chosen at random from outdoor paediatrics department Madina Teaching Hospital, Faisalabad, during December 2021 June 2022 and assigned receive either oral 600,000 IU three doses on same day or intramuscular IU. Vitamin x-rays as a baseline. At 30-day mark, we checked with every one kids again....

10.53350/pjmhs22168658 article EN 2022-08-31

Objective: To comparison of the efficacy dapagliflozin+metformin versus sitagliptin+metformin: in newly diagnosed type 2 diabetes Methodology: In this Randomized Control Trial, we enrolled a total 180 cases; 90 cases mellitus (HbA1c>6.5) two equal groups A&B on basis computer-generated randomization table. Group A was allotted to 100mg q.d sitagliptin plus 850 mg addition 500mg metformin times day. Patients B were advised for 10mg qd dapagliflozin+500mg day six months. followed up...

10.53350/pjmhs221610459 article EN Pakistan Journal of Medical & Health Sciences 2022-10-30

Postpartum haemorrhage is a leading cause of severe maternal morbidity and mortality in both developed developing countries. We aimed to determine the frequency women with primary postpartum hemorrhage. This descriptive case study was conducted at Department Obstetrics & Gynecology, Allied Hospital, Faisalabad, from 15th September 2018 14th March 2019. A total 241 PPH, having age 18-40 years, gestational 37- 41 weeks were recruited. Patients evaluated for presence sepsis, disseminated...

10.31580/pjmls.v4i4.2441 article EN cc-by Pak-Euro Journal of Medical and Life Sciences 2021-12-31
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