A5055413566- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Prenatal Screening and Diagnostics
- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive Health and Technologies
- SARS-CoV-2 detection and testing
- SARS-CoV-2 and COVID-19 Research
- Animal Genetics and Reproduction
- Pregnancy and Medication Impact
- Hepatitis B Virus Studies
- Pregnancy and preeclampsia studies
- Chromosomal and Genetic Variations
- MicroRNA in disease regulation
- Biosensors and Analytical Detection
- Renal and related cancers
- HIV/AIDS drug development and treatment
- Effects and risks of endocrine disrupting chemicals
- Ectopic Pregnancy Diagnosis and Management
- Mosquito-borne diseases and control
- Hepatitis C virus research
- Respiratory viral infections research
- Social Policies and Family
Pierre Fabre (France)
2023
Hôpital Cochin
2011
Groupe Hospitalier Diaconesses Croix Saint-Simon
2011
Jones Institute
2010
Eastern Virginia Medical School
2010
University of Córdoba
2010
Cornell University
2010
Institut Mérieux (France)
2003
Hôpital Bichat-Claude-Bernard
2002
Université Claude Bernard Lyon 1
2002
Sperm samples are separated into bad and good quality in function of their phenotype, but this does not indicate genetic quality. Here, we used GeneChip miRNA arrays to analyze microRNA expression ten semen selected based on high-magnification morphology (score 6 vs. score 0) identify miRNAs linked sperm phenotype. We found 86 upregulated 21 downregulated good-quality 6) compared with bad-quality (fold change > 2 p-value < 0.05). MiR-34 (FC × 30, p = 8.43 10-8), miR-30 12, 3.75 10-6),...
To assess the efficiency of endometrial immune profiling as a method to design personalized care enhance pregnancy rate in large heterogeneous infertile population. We hypothesized that some reproductive failures could be induced by uterine dysregulation which identified and corrected with targeted plan.
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic has become a major public health issue worldwide. Developing and evaluating rapid easy‐to‐perform diagnostic tests is high priority. current study was designed to assess the performance of an antigen‐based detection test (COVID‐VIRO®) in real‐life setting. Two nasopharyngeal specimens symptomatic or asymptomatic adult patients hospitalized Infectious Diseases Department voluntarily accessing COVID‐19 Screening...
This study compared prevalence rates of health-compromising behaviors among boys and girls from different ethnic backgrounds in early, middle, late adolescence co-occurrences such across gender groups.The population included 123 132 adolescents grades 6, 9, 12. Adolescents completed a classroom-administered statewide survey focusing on high-risk behaviors, including unhealthy weight loss, substance abuse, suicide risk, delinquency, sexual activity.Prevalence most differed by gender,...
To control the spread of coronavirus disease 2019 (COVID-19) epidemics, it is necessary to have easy-to-use, reliable diagnostic tests available. The nasopharyngeal sampling method being often uncomfortable, nasal could prove be a viable alternative reference method. We performed multicentre, prospective validation study COVID-VIRO® test, using swab method, in point-of-care setting. In addition, we prospective, and usability validate use rapid antigen test by laypersons. March 2021, 239...
Despite advancements in assisted reproductive treatments, 70% of transferred embryos fail to implant successfully, yielding significant personal and global repercussions. One promising avenue research is take into account the individual's immune uterine profile order tailor treatment optimise outcomes. This randomised controlled trial represents initial exploration consequences disregarding state environment infertile women embarking on IVF/ICSI. open two-arm included IVF patients, with...
Objective . To analyze DNA methylation levels between two groups of spermatozoa taken from the same sample, following morphological selection by high magnification (HM) at 6100x microscopy. A prospective study was conducted and studied 876 10 randomly selected men. Sperm morphology characterized HM according to criteria previously established. High-scoring Score 6 low-scoring 0 sperm were selected. level assessed using an immunoassay method targeting 5-methylcytosine residues fluorescence...
The control of the COVID-19 epidemics has been one global health priorities for last 2 years. To that end, more reliable and easy-to-use, regardless age, diagnostic tests are necessary. Considering that, we evaluated an innovative two-step self-test, AAZ COVID-VIRO ALL IN®, switching from classic nasal swab to a sponge. We performed multicenter study, on 124 adults children, in point-of-care setting. Sensitivity, specificity overall acceptance IN® self-test compared reverse transcriptase...
Abstract STUDY QUESTION Is there a cumulative toxicity of disposables used in IVF procedures? SUMMARY ANSWER A may be detected when consumables are cumulatively, while no is the same and tested individually. WHAT IS KNOWN ALREADY Many components items laboratories impair human embryonic development. Consequently, it necessary to screen all reagents materials which could contact with gametes embryos. Toxicity tests, such as mouse embryo assay sperm motility (HSMA), by manufacturers quality...
Our objective was to use an adapted RT-PCR technique assess the presence of hepatitis C virus (HCV) in semen and also different density gradient fractions collected from men with chronic viral participating assisted reproduction programme.This study included 50 samples 35 HCV(+) men, active replication assessed by RT-PCR, day oocyte retrieval used for reproduction. These were subjected standard sperm preparation conditions, using density-gradient centrifugation 45 90% layers. Aliquots semen,...
Choosing spermatozoa with an optimum fertilizing potential is one of the major challenges in assisted reproductive technologies (ART). This selection mainly based on semen parameters, but addition molecular approaches could allow a more functional evaluation. To this aim, we used sixteen fresh sperm samples from patients undergoing ART for male infertility and classified them high‐ poor‐quality groups, basis their morphology at high magnification. Then, using DNA sequencing method, analyzed...
ABSTRACT The discrepant results available in the literature about presence of hepatitis C virus (HCV) RNA seminal plasma men chronically infected by this agent are related, at least part, to molecular techniques used and particularly wide range protocols dedicated extraction. In order evaluate these standardize method detection HCV fluid, a panel coded specimens was tested blindly 12 French laboratories; it included 14 four water controls spiked with ranging from 10 20,000 IU/ml two...