Alexander Friedrich

ORCID: 0000-0002-4587-7901
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About
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Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Neuroendocrine Tumor Research Advances
  • Clinical Nutrition and Gastroenterology
  • Nutrition and Health in Aging
  • Lung Cancer Research Studies
  • Natural product bioactivities and synthesis
  • Phytochemicals and Antioxidant Activities
  • Colorectal Cancer Treatments and Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Renal cell carcinoma treatment
  • Oral health in cancer treatment
  • Colorectal and Anal Carcinomas
  • Organ Transplantation Techniques and Outcomes
  • Intraperitoneal and Appendiceal Malignancies
  • Cancer Diagnosis and Treatment
  • Chromatography in Natural Products
  • Transplantation: Methods and Outcomes
  • Metabolism, Diabetes, and Cancer
  • Pharmacological Effects and Toxicity Studies
  • Surgical site infection prevention
  • Gastric Cancer Management and Outcomes
  • Surgical Sutures and Adhesives
  • Viral Infections and Immunology Research
  • Brain Metastases and Treatment

Medical University of Vienna
2022-2025

University of Göttingen
2012

University of Münster
2008

As the bioavailability of flavonoids is influenced by intestinal metabolism, we have investigated microbial deconjugation and degradation several flavonols flavonol glycosides using pig cecum in vitro model system developed our group. For this microbiota was directly isolated from cecal lumen freshly slaughtered pigs. The characterization fluorescence situ hybridization (FISH) with 16S rRNA-based oligonucleotide probes confirmed suitability for studying metabolism human microbiota. We...

10.1021/jf073444o article EN Journal of Agricultural and Food Chemistry 2008-02-28

Malignant ascites is common in metastatic pancreatic cancer (mPC) and its management still remains a clinical challenge. Early identification of patients at risk for development may support guide treatment decisions.Data treated mPC the Medical University Vienna between 2010 2019 were collected by retrospective chart review. Ascites was defined as clinically relevant accumulation intraperitoneal fluid diagnosed ultrasound or computer tomography scan abdomen. We investigated association...

10.1016/j.esmoop.2023.101200 article EN cc-by ESMO Open 2023-03-28

Identification of factors associated with survival after ascites diagnosis in metastatic pancreatic cancer (mPC) patients may guide treatment decisions and help to maintain quality life this highly symptomatic patient collective.

10.1016/j.esmoop.2023.102048 article EN cc-by ESMO Open 2023-11-16

While colorectal and gastroesophageal cancer represent the two gastrointestinal (GI) tumor entities with highest incidence of brain metastatic (BM) disease, data on clinical course BM patients from hepatopancreatobiliary malignancies are rare. Patients cholangiocarcinoma (CCA), hepatocellular carcinoma (HCC), pancreatic ductal adenocarcinoma (PDAC) gastroenteropancreatic neuroendocrine neoplasms (GEP NEN). Treated for between 1991 2017 at an academic care center were included. Brain...

10.1007/s10585-023-10201-1 article EN cc-by Clinical & Experimental Metastasis 2023-03-22

Background: Parenteral nutrition is controversial in patients with advanced cancer. Nevertheless, this treatment common practice near the end of life. Aim: We aimed to identify factors which were associated outcome on parenteral at an academic tertiary palliative care unit. Design: In retrospective cohort study assigned two groups according treatment. Inferential statistics used assess whether dynamics laboratory variables over 2 weeks survival. Setting/Participants: Patients admitted...

10.1177/02692163211073939 article EN cc-by Palliative Medicine 2022-02-20

Parenteral nutrition (PN) is frequently administered in palliative care patients suffering from cachexia. The evidence regarding the use of PN terminally ill scarce. Routine laboratory parameters might help to decide whether start or forgo PN, which could decrease overtreatment at end life. Kidney failure was associated with survival. However, a relation between kidney function and parenteral has not been observed thus far. aim this retrospective cohort study analyze under as well these overall

10.3390/nu14040769 article EN Nutrients 2022-02-11
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