A5047447631- Toxoplasma gondii Research Studies
- Cytomegalovirus and herpesvirus research
- Viral Infections and Vectors
- Hepatitis C virus research
- Olfactory and Sensory Function Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Liver Disease Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Urban Stormwater Management Solutions
- SARS-CoV-2 detection and testing
- Bacteriophages and microbial interactions
- Hepatitis B Virus Studies
- Flood Risk Assessment and Management
- interferon and immune responses
- Long-Term Effects of COVID-19
- Hydraulic flow and structures
Guangzhou Medical University
2024-2025
Guangzhou Institutes of Biomedicine and Health
2024-2025
First Affiliated Hospital of Guangzhou Medical University
2024
State Key Laboratory of Respiratory Disease
2024
Chinese Academy of Sciences
2024
Hangzhou Medical College
2021-2022
Zhejiang Academy of Medical Sciences
2020-2021
Chongqing Jiaotong University
2018
SARS-CoV-2-induced excessive inflammation in brain leads to damage of blood-brain barrier, hypoxic-ischemic injury, and neuron degeneration. The production inflammatory cytokines by microvascular endothelial cells microglia is reported be critically associated with the pathology COVID-19 patients. However, cellular mechanisms for SARS-CoV-2-inducing activation subsequent neuroinflammation remain fully delineated. Our research, along others', has recently demonstrated that accumulation mast...
Naf1 (Nef-associated factor 1) is a host protein that interacts with human immunodeficiency virus type 1 (HIV-1) Nef protein. We and others have previously demonstrated restricts HIV-1 infection of T-lymphocytes. Myeloid cells are targets for HIV infection, but expression in myeloid whether it also regulates these not yet identified. In this study, we found had higher CD14+ monocytes than monocyte-derived dendritic (MDDCs), its both types could be induced by gp120 glycoproteins or viral...
Toxoplasma gondii is an obligate intracellular protozoan parasite that causes toxoplasmosis and threatens warm-blooded animal human health worldwide. Simple applicable diagnostic methods are urgently needed to guide development of effective approaches for prevention toxoplasmosis. Most molecular tools T. infection require high technical skills, sophisticated equipment, a controlled lab environment. In this study, we developed loop-mediated isothermal amplification-lateral-flow-dipstick...
The coronavirus disease 2019 (COVID-19) is outbreaking all over the world. To help fight this disease, it necessary to establish an effective and rapid detection method. nucleocapsid (N) protein of severe acute respiratory syndrome 2 (SARS-CoV-2) involved in viral replication, assembly, immune regulation plays important role life cycle. Moreover, N also could be a diagnostic factor potential drug target. Therefore, by synthesizing gene sequence SARS-CoV-2, constructing pET-28a (+)-N...
Bioretention can be an effective measure for stormwater treatment. However, there is a lack of systematic analysis the impact bioretention design parameters on hydrologic performance. Herein, SWMM and RECARGA models were applied to generate typical annual rainfall runoff simulate water balance system in expressway service area. The purpose investigation was identify key delineate priorities developing design. Results showed that average groundwater recharge ratios basins with without...
Abstract Background: Toxoplasma gondii ( T. ) is worldwide spread caused Toxoplasmosis threatening warm-blooded animal and human health, especially for immunodeficient population pregnant women. Simple applicable diagnostic methods are urgently needed the prevention of toxoplasmosis. The molecular diagnosis infection generally requires high technical skills, sophisticated equipment a controlled lab environment. Methods: In this study, we developed loop-mediated isothermal...