A5052022545- Global Cancer Incidence and Screening
- Health Policy Implementation Science
- Smoking Behavior and Cessation
- Hereditary Neurological Disorders
- Cancer Risks and Factors
- COVID-19 and healthcare impacts
- Advances in Oncology and Radiotherapy
- Cellular transport and secretion
- Healthcare Systems and Technology
- Primary Care and Health Outcomes
- Colorectal Cancer Screening and Detection
- Neurogenetic and Muscular Disorders Research
- Endoplasmic Reticulum Stress and Disease
- Cancer survivorship and care
- Health Promotion and Cardiovascular Prevention
- Interprofessional Education and Collaboration
- Genetic Neurodegenerative Diseases
- Health and Medical Research Impacts
- Economic and Financial Impacts of Cancer
University of Wisconsin–Madison
2018-2024
University of Wisconsin Carbone Cancer Center
2021-2023
Quitting smoking improves patients' clinical outcomes, yet is not commonly addressed as part of cancer care. The Cancer Center Cessation Initiative (C3I) supports National Institute-designated centers to integrate tobacco treatment programs (TTPs) into routine C3I vary in size, implementation strategies used, and approaches. We examined associations these contextual factors with reach cessation effectiveness.
Length-dependent axonopathy of the corticospinal tract causes lower limb spasticity and is characteristic several neurological disorders, including hereditary spastic paraplegia (HSP) amyotrophic lateral sclerosis. Mutations in Trk-fused gene (TFG) have been implicated both diseases, but pathomechanisms by which these alterations cause neuropathy remain unclear. Here, we biochemically genetically define impact a mutation within TFG coiled-coil domain, underlies early-onset forms HSP. We find...
Delivering evidence-based tobacco dependence treatment in oncology settings improves smoking abstinence and cancer outcomes. Leadership engagement/buy-in is critical for implementation success, but few studies have defined buy-in or described how to secure programs (TTPs) care. This study examines during the establishment of at National Cancer Institute (NCI)-designated centers. We utilized a sequential, explanatory mixed-methods approach analyze quantitative data qualitative interviews with...
Background: Recent reports suggest that racial differences in breast cancer incidence rates have decreased. We examined whether these findings apply to mortality while considering age, period, and cohort influences on both absolute relative measures of mortality. Methods: Using publicly available datasets (CDC WONDER, Human Mortality Database), we developed an age–period–cohort model deaths as a proportion all during 1968–2019 among women by 5 race/ethnicity groups with sufficient numbers...
Abstract Introduction The COVID-19 pandemic disrupted cancer screening and treatment delivery, but COVID-19’s impact on tobacco cessation for patients who smoke has not been widely explored. Aims Methods We conducted a sequential cross-sectional analysis of data collected from 34 National Cancer Institute (NCI)-designated centers participating in NCI’s Center Cessation Initiative (C3I), across three reporting periods: one prior to (January–June 2019) two during the 2020, January–June 2021)....
In 2017, the National Cancer Institute (NCI) funded Center Cessation Initiative (C3I) to implement and expand tobacco treatment programs in routine oncology care. Many C3I developed specialty care staffed by specialists (TTSs) deliver evidence-based adult patients who smoke. People involved can help identify implementation strategies adaptations that may enhance reach effectiveness cancer more with quit using tobacco.
Background Cancer patients who receive evidence-based tobacco-dependence treatment are more likely to quit and remain abstinent, but tobacco programs (TTPs) not consistently offered. In 2017, the U.S. National Institute, through Moonshot, funded Center Cessation Initiative (C3I). C3I supports 52 cancer centers implement expand in routine oncology care. Integration into care involves use of health information technology (IT), including modifying electronic records clinical workflows. Here, we...
Length-dependent axonopathy of the corticospinal tract causes lower limb spasticity and weakness is characteristic several neurological disorders, including hereditary spastic paraplegia (HSP) amyotrophic lateral sclerosis (ALS). Mutations in tropomyosin-receptor kinase fused gene (TFG) have been implicated both disease states, but pathomechanisms by which these alterations cause neuropathy remain unclear. Here, we biochemically genetically define impact a mutation within coiled coil domain...