A5078084142- Immune Response and Inflammation
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- vaccines and immunoinformatics approaches
- interferon and immune responses
- Herpesvirus Infections and Treatments
- HIV Research and Treatment
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Immune cells in cancer
University of Edinburgh
2020-2024
University of Cambridge
2016-2022
Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well a public health concern due zoonotic pathogens. Unlike typical mammals, histocompatibility complex (MHC) can confer decisive resistance or susceptibility many viral diseases. An iconic example is Marek’s disease, caused by oncogenic herpesvirus with over 100 genes. Classical MHC class I II molecules present antigenic peptides T lymphocytes, it has been...
B-cell adaptor protein (BCAP) is a multimodular, multifunctional signal transducer that regulates transduction pathways in leukocytes, including macrophages, B-cells, and T-cells. In particular, BCAP suppresses inflammatory signaling by Toll-like receptors (TLRs). However, how itself regulated what its interaction partners are unclear. Here, using human immune cell lines, THP-1 cells, we characterized the complex phosphorylation patterns of used novel trapping strategy, called virotrap, to...
Abstract Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well a public health concern due zoonotic pathogens. Unlike typical mammals, histocompatibility complex (MHC) can confer decisive resistance or susceptibility many viral diseases. An iconic example is Marek’s disease, caused by oncogenic herpesvirus with over 100 genes. Classical MHC class I II molecules present antigenic peptides T lymphocytes, it...