A5064393241- Diabetes and associated disorders
- Diabetes Management and Research
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Diabetes Management and Education
- COVID-19 Clinical Research Studies
- Diet, Metabolism, and Disease
- Health Literacy and Information Accessibility
- Birth, Development, and Health
- Sexual Differentiation and Disorders
- Thyroid Disorders and Treatments
- Dietary Effects on Health
- Growth Hormone and Insulin-like Growth Factors
- Innovations in Medical Education
- Chronic Disease Management Strategies
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Mobile Health and mHealth Applications
- Pharmacology and Obesity Treatment
- Social Media in Health Education
- Liver Disease Diagnosis and Treatment
- Soft tissue tumor case studies
- Clinical Reasoning and Diagnostic Skills
- Web and Library Services
- Educational Environments and Student Outcomes
Kuwait University
2014-2024
Dasman Diabetes Institute
2019-2024
Ministry of Health
2019-2024
Mubarak Al Kabeer Hospital
2019-2021
Farwaniya Hospital
2015
Hospital for Sick Children
2009-2013
Approved treatments for type 2 diabetes in pediatric patients include metformin, liraglutide, and insulin. However, approximately one-half of the youth fail metformin monotherapy within 1 year, insulin therapy is associated with challenges, liraglutide requires daily injections. Consequently, efficacy safety once-weekly injections exenatide treatment was evaluated.Participants (aged 10 to <18 years) were randomized (5:2) mg or placebo, respectively. The primary end point change glycated...
Abstract We examined the frequency and severity of diabetic ketoacidosis (DKA) in 679 children adolescents (0–14 years) at diagnosis Type 1 Diabetes Mellitus (T1DM) Kuwait. Between st January 2011 31 December 2013, all newly diagnosed with diabetes were registered prospectively a population-based electronic register. DKA was using standard criteria based on levels venous pH serum bicarbonate. At time diagnosis, mild/moderate present 24.8% children, while severe 8.8%. Incidence significantly...
AIMS This study had 2 aims: to report data on the incidence of childhood-onset type 1 diabetes in Kuwaiti children aged 0-14 years during 2011 2013 and compare recent with those collected 1992 1997. METHODS All newly diagnosed patients were registered through Childhood-Onset Diabetes eRegistry (CODeR) 2011-2013, based DiaMond protocol used 1992-1997. RESULTS A total 515 (247 boys 268 girls) from January 31 December 2013. Data ascertainment 96.7%. The mean age ± SD at diagnosis was 8.7 3.4...
Objective: In recent decades, the Arab population has experienced an increase in prevalence of type 2 diabetes (T2DM), particularly within Gulf Cooperation Council. this context, early intervention programmes rely on ability to identify individuals at risk T2DM. We aimed build prognostic models for T2DM using machine-learning algorithms vs. conventional logistic regression (LR) and simple non-invasive clinical markers over three different time scales (3, 5, 7 years from baseline). Design:...
Abstract Introduction The COVID‐19 pandemic might have a multifaceted effect on children with type 1 diabetes (T1D), either directly through infection itself or indirectly due to measures implemented by health authorities control the pandemic. Objective To compare data newly diagnosed T1D in Kuwait during pre‐pandemic period. Research Design and Methods We analysed aged 12 years less registered Childhood‐Onset Diabetes electronic Registry (CODeR) Kuwait. Data were incidence rate (IR),...
Professionalism is a core competency in the medical profession worldwide. Numerous studies investigate how this taught and learned. However, there are few reports on students' views experiences with professionalism especially Arab world. Our aim was to explore of Kuwait final-year students professionalism. This questionnaire study at University (n = 95). Open- close-ended questions were used determine on: definition, teaching, learning, assessment Eighty-five completed (89.5%). A total 252...
Abstract Genetic variants responsible for Maturity-Onset-Diabetes of the Young (MODY) in Kuwait were investigated. A newly established a National Referral Clinic, Dasman Diabetes Institute (DDI-NRC), assessed forty-five members from 31 suspected MODY families by whole exome sequencing. Thirty-three 45 samples independently sequenced at DDI-NRI, Exeter University, UK ( https://www.diabetesgenes.org/ ) using targeted 21-gene panel approach. Pathogenic mutations GCK, HNF1A, HNF1B, HNF4A, and...
Abstract Aims This study reports the prevalence and characteristics related to development of thyroid autoimmunity among children newly diagnosed with type I diabetes (T1D) during COVID‐19 pandemic in Kuwait. Materials Methods is a prospective observational all under age 14 years T1D We define duration from official declaration first identified positive case on 24 February 2020 until 31 December 2022. For comparison, we use time period directly before pandemic, 1 January 2017 23 2020....
Educational environment of an institution affects the quality learning. We aim to assess educational undergraduate curriculum Faculty Medicine, Kuwait University (FOMKU).A cross-sectional study was carried out during April 2014. The validated Dundee Ready Education Environment Measure (DREEM) questionnaire e-mailed 607 students. Mean scores main domains questionnaire, and for each item, were calculated, their association with students' background information measured using Student's t-test...
Hyperparathyroidism Jaw-Tumour Syndrome (HPT-JT) is characterized by primary hyperparathyroidism (PHPT), maxillary/mandible ossifying fibromas and parathyroid carcinoma in 15% of cases. Inactivating mutations the tumour suppressor CDC73/HRPT2 gene have been found HPT-JT patients also as genetic determinants sporadic carcinoma/atypical adenomas and, rarely, typical adenomas, familial PHPT. Here we report molecular analysis three affected PHPT due to atypical one case belonging Flag-tagged WT...
Continuous subcutaneous insulin infusion (CSII) and multiple daily injections (MDI) are two methods currently used to manage type I diabetes mellitus (T1DM). Here we compare our experiences with CSII MDI in a large cohort of pediatric patients Kuwait.Data on 326 T1DM who were started between 2007 2012 retrospectively compared those MDI. They matched for sex, age at diagnosis, duration, glycemic control, requirement, body mass index (BMI). Data collected baseline every three months included...
Recombinant Growth hormone (rGH) therapy is approved in many countries for treatment of short stature a number childhood diagnoses. Despite the increasing body international literature on rGH use, there paucity data use Kuwait and broader Middle-East which share unique ethnic socio-cultural backgrounds. This study aimed to describe pattern outcomes Kuwait.This cross-sectional retrospective review children treated with Department Pediatrics, major hospital between December 2013 2014. Data...
Background To evaluate the safety of fasting during holy month Ramadan among children and adolescent with type 1 diabetes (T1D). Methods A retrospective cohort study 50 adolescents T1D whose mean age was 12.7 ± 2.1 years conducted. Twenty-seven patients (54%) were on multiple daily injections (MDI) insulin regimen 23 (46%) pump therapy. Before for Ramadan, their families evaluated educated about management Ramadan. Hemoglobin A1c (HbA1c), weight, number days fasted, hypoglycemia...
Background: Type 2 Diabetes (T2D) in children and adolescents has become an important public health concern due to the increase childhood obesity worldwide. The urgency address T2D is evident as are at a higher risk of complications prolonged disease duration. We aimed estimate incidence rate (IR) Kuwaiti aged 14 years younger between 2011-2013 describe their clinical characteristics time diagnosis. Material Methods: All newly diagnosed patients were registered through Childhood-Onset...
Background: Celiac disease (CD) is a chronic inflammatory of the small intestine triggered by gluten ingestion. The objective this study to describe our experience with CD children in Kuwait. Methods: records seen pediatric gastroenterology unit between February 1998 and December 2010 were retrospectively reviewed. Patients referred because symptoms or positive antibody screening high-risk group (type 1 diabetes Down syndrome). Results: Forty-seven patients diagnosed: 53% symptomatic 47%...
With the rapid transmission of COVID-19 globally, countries have implemented strict governmental measures and social distancing rules that aimed to minimize spread virus. School closures, quarantine orders, isolation, coupled with a surge in family stress lack peer interactions, are probable causes mental health complications psychological symptoms faced by children. This study aims at comparing HRQoL children adolescents type 1 diabetes (T1D) affected infection (personal or familial) those...
Background: The aim of the study was to describe referral pattern, baseline characteristics, and etiological profile children referred with short stature in Kuwait.
The "accelerator hypothesis" predicts early onset of Type 1 diabetes (T1D) in heavier children. Studies testing direction correlation between body mass index (BMI) and age at T1D different continental populations have reported differing results-inverse, direct, neutral. Evaluating the diverse ethnic is required to generalize accelerator hypothesis.The study cohort comprised 474 Kuwaiti children Arab ethnicity diagnosed with 6 18 years during 2011-2013. Age- sex-adjusted BMI z-scores were...
Background: Lockdown was a unique experience that affected many aspects of life, particularly during the challenge Ramadan fasting (RF). Studying this can increase understanding effects lifestyle changes on quality life (QoL) for children with type 1 diabetes (T1D) RF. Methods: A cross-sectional study assessed effect lockdown and QoL living T1D in Middle East North Africa region (2020-2021). We compared child (self) parent (proxy) reports using PEDQoL v3.0 disease specific questionnaire...
Monitoring the trends in presentation of T1D over decades cannot be underestimated as it provides a rich source information on diabetes-related complications like DKA. DKA represents medical emergency, with potentially fatal outcome, and thus prevention is priority diabetes care. The aim this study to report children newly diagnosed Kuwait.This based retrospective review aged 14 years or less at three Governmental Hospitals representing health sectors out total six country during period...
Purpose The purpose of the study was to assess feasibility use and reliability Arabic version Newest Vital Sign (NVS-Ar) in parents children with type 1 diabetes (T1D). Methods final translated NVS-Ar administered 175 adult caregivers T1D who are native speakers. association between scores for parents/legal guardians A1C their assessed. internal consistency evaluated by Cronbach’s α, assessed test-retest method. Results median (interquartile range) score 4.0 (3-5). moderate (α = .58)....