A5075478425- Arsenic contamination and mitigation
- Heavy Metal Exposure and Toxicity
- Epigenetics and DNA Methylation
- Advanced biosensing and bioanalysis techniques
- SARS-CoV-2 and COVID-19 Research
- Gene expression and cancer classification
- Telomeres, Telomerase, and Senescence
- Animal Vocal Communication and Behavior
- Primate Behavior and Ecology
- Heavy metals in environment
- Air Quality and Health Impacts
- Ovarian function and disorders
- RNA Research and Splicing
- Microplastics and Plastic Pollution
- Selenium in Biological Systems
- Healthcare and Environmental Waste Management
- Carcinogens and Genotoxicity Assessment
- MicroRNA in disease regulation
- Glioma Diagnosis and Treatment
- Adipose Tissue and Metabolism
- Occupational and environmental lung diseases
- Health, Environment, Cognitive Aging
- Genomics, phytochemicals, and oxidative stress
- Glutathione Transferases and Polymorphisms
- Chromium effects and bioremediation
University of Calcutta
2016-2025
University of Zurich
2019-2023
Institut de Génétique Moléculaire de Montpellier
2019-2022
Université de Montpellier
2022
Epigenomics (Germany)
2022
Indian Institute of Chemical Biology
2011-2013
Council of Scientific and Industrial Research
2011
Abstract Arsenic in drinking water may cause major deleterious health impacts including death. Although arsenic rice has recently been demonstrated to be a potential exposure route for humans, there date no direct evidence the impact of such on human health. Here we show first time, through cohort study West Bengal, India, involving over 400 subjects not otherwise significantly exposed water, elevated genotoxic effects, as measured by micronuclei (MN) urothelial cells, associated with staple...
The gene for glutathione-S-transferase (GST) M1 (GSTM1), a member of the GST-superfamily, is widely studied in cancer risk with regard to homozygous deletion (GSTM1 null), leading lack corresponding enzymatic activity. Many these studies have reported inconsistent findings regarding its association risk. Therefore, we employed silico, vitro and vivo approaches investigate whether absence functional GSTM1 enzyme null variant can be compensated by other family members. Through silico approach,...
The pandemic COVID-19 outbreak has been caused due to SARS-CoV-2 pathogen, resulting in millions of infections and deaths worldwide, the United States being on top at present moment. long, complex orf1ab polyproteins play an important role viral RNA synthesis. To assess impact mutations this domain, we analyzed 1134 complete protein sequences polyprotein from NCBI virus database affected patients across various states December 2019 25 April 2020. Multiple sequence alignment using Clustal...
Ectopic fat deposition is more strongly associated with obesity-related health problems including type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), hypothyroidism, arthritis, etc. Our study aimed at identifying the cumulative role of several risk factors in developing obesity and ectopic (visceral fat) predicting disease varied age groups among urban adult academic professionals West Bengal. 650 adults (Male = 456; Female 194) job (age 20-65 years) Bengal were randomly selected...
Abstract Menstruation is a natural phenomenon for every female, starting from adolescents to menopausal age. Any disturbances in menstrual patterns can eventually affect one’s physical as well psychological health which turn hamper the quality of life women. Several factors including genetic predisposition lifestyle modifications adversely normal patterns. Hence, this study aims evaluate prevalence disorders among and young women associated risk factors. A cross-sectional random survey was...
Arsenic (As) induces pre-malignant and malignant dermatological lesions, non-dermatological health effects cancers in humans. Senescence involves telomere length changes acquisition of senescence-associated secretory phenotype (SASP), which promotes carcinogenesis. Though vitro studies have shown that As senescence, population based are lacking. We investigated the arsenic-induced alteration its contribution towards development As-induced skin cancer. The study participants included 60 each...
Urbanization has drastically altered natural habitats, forcing non-human primates (NHPs) to adapt human-modified environments. This study examines one such adaptation undertaken by free-ranging Hanuman langurs residing in Dakshineswar, a temple area and tourist hub West Bengal. Our observations reveal that they have come up with solicitation behaviors resembling human begging wherein ask for food from nearby humans using various gestures. Notably, we identified seven distinct 'begging'...
Background: The brain tumour classification of WHO in 2016 introduced molecular characterization samples with histopathology, and that was further elaborated 2021. Detecting the characteristic state to promote prognostic outcome is now a key interest area present cancer research. This work aims explore such important aspects from low-grade post-operative CNS samples. Methods: Post-ablative tumours were collected hospital patient metadata, identified graded histopathologically. They...
Tea is the most popularly consumed beverage in world. Theaflavin and thearubigins are key bioactive compounds of black tea that have anticarcinogenic properties as reported several studies. However, epigenetic potential these has not yet been explored. DNA methyltransferase (DNMT) enzymes induce methylation at cytosine residues play a significant role regulation cancer therapy. The present study explored DNMT inhibitor prevention cancer. Herein, effect theaflavin studied colon cell line...