A5010726956- Toxic Organic Pollutants Impact
- Petroleum Processing and Analysis
- Mass Spectrometry Techniques and Applications
- Effects and risks of endocrine disrupting chemicals
- Microbial bioremediation and biosurfactants
- Air Quality and Health Impacts
- Pesticide Exposure and Toxicity
- Molecular Sensors and Ion Detection
- Environmental Toxicology and Ecotoxicology
- Pesticide Residue Analysis and Safety
- Analytical Methods in Pharmaceuticals
- Microplastics and Plastic Pollution
- Chromatography in Natural Products
- Electrochemical Analysis and Applications
- Forensic Fingerprint Detection Methods
- Carcinogens and Genotoxicity Assessment
- NMR spectroscopy and applications
- Environmental remediation with nanomaterials
- Pharmacogenetics and Drug Metabolism
- Atmospheric chemistry and aerosols
- Isotope Analysis in Ecology
Siemens (Germany)
2025
University of Tübingen
2025
University of Hohenheim
2017-2022
Abstract Over the last decades, short-chain chlorinated paraffins (SCCPs), medium-chain (MCCPs), and long-chain (LCCPs) have become most heavily produced monomeric organohalogen compound class of environmental concern. However, knowledge about their toxicology is still scarce, although SCCPs were shown to effects on thyroid hormone system. The lack data in case MCCPs LCCPs structural similarity with perfluoroalkyl substances (PFAS) prompted us test CPs novel TTR-TR CALUX assay for transport...
Background: Malignant ascites is a common complication of advanced ovarian and gastrointestinal cancer, significantly affecting metastasis, patient quality life, survival. In here, increased intestinal permeability cannot only result in blood or lymph infiltration but also microbial translocation from the uterine tract. This study aimed to discover microbiota-derived metabolites cancer stages II-III, IV, assess discuss their potential roles tumor progression aggressiveness. Methods: an...
Chlorinated paraffins (CPs) are a group of man-made pollutants growing environmental concern. Short-chain chlorinated (SCCPs) were recently classified as persistent organic (POPs), while medium-chain (MCCPs) still unregulated. Foodstuff is major pathway for the human CP intake, and regular diet has been analyzed in several studies recently. However, dietary supplements (DS) had not on CPs. Our goal was to investigate occurrence CPs DS evaluate possible threat consumers. (n = 25) made from...
Abstract Chlorinated paraffins (CPs) are high-volume chemicals used worldwide in various industries as plasticizers, lubricants, and flame retardants. CPs produced by chlorination of alkane mixtures which leads to complex products thousands homologs congeners. Classic mass spectrometric analyses allow determining carbon chain lengths degrees while information on the substitution patterns cannot be derived. Therefore, we performed different one- two-dimensional nuclear magnetic resonance...
Rationale Quantification of chlorinated paraffins (CPs) via gas chromatography coupled with electron capture negative ionization low‐resolution mass spectrometry (GC/ECNI‐MS) is a very common practice, although the quality results has been disputed due to insufficient resolution and strong impact degree chlorination on GC/ECNI‐MS response. Methods For further tests we synthesized eight single chain length CP standards (C 10 –C 17 ) chlorine contents between 51.1% 61.3%. The individual...
The photolytic transformation of decabromodiphenyl ethane-a current-use brominated flame retardant and major substitute the structurally related ether-was investigated in different solvents (toluene, dichloromethane, chlorobenzene, benzyl alcohol). rate followed pseudo first order kinetics, with increasing half-life ( t1/2) toluene t1/2 = 4.6 min), chlorobenzene 14.0 dichloromethane 27.9 alcohol ≈ 60 min). Formation amount products varied depending on solvent used. A detailed study...
Abstract Chlorinated paraffins (CPs) are anthropogenic pollutants of growing environmental concern. These highly complex mixtures thousands homologs and congeners usually applied as additives in lubricants or flame retardants plasticizers polymers paints. Recent studies indicated the presence high amounts CPs kitchen environment whose sources could not be unequivocally identified. One option was use hinges. To test this hypothesis, we performed wipe tests on 29 hinges different types...
Technical chlorinated paraffins (CPs) are produced via radical chlorination of n-alkane feedstocks with different carbon chain-lengths (∼C10-C30). Short-chain CPs (SCCPs, C10-C13) classified as persistent organic pollutants (POPs) under the Stockholm Convention. This regulation has induced a shift to use longer-chain substitutes. Consequently, medium-chain (MCCPs, C14-C17) and long-chain (LCCPs, C>17) have become dominant homologues in recent environmental samples. However, no suitable...
Chlorinated paraffins (CPs) have been repeatedly detected in the kitchen environment. Especially baking ovens were contaminated with high CP amounts on insides of doors. To investigate if CPs could be transferred into baked food, we spiked self-synthesized single chain C12-CP and C15-CP standards onto inside door an unused, CP-free oven. Experiments performed under different conditions to assess possible transportation pathways. Coconut fat was used as food simulant, exhaust air monitored...