Background: The relationship between radiologic instability and its symptoms is controversial. Previous authors consider flexion–extension radiographs to be of little value in evaluating instability; however, the current variation results result limitations previous researchers' methods. Methods: In this report, sagittal translation angulation at L4–L5 segment were measured films 1090 outpatients with low back and/or leg pain using a three-landmark measuring method. four groups without 3-mm...

A prospective study involving 56 patients with cervical spondylotic myelopathy (CSM) was conducted.To investigate the outcomes and prognostic factors for CSM after nonsurgical treatment.The superiority of surgical treatment over has not been confirmed in mild forms CSM. Outcomes are well understood.Clinical signs symptoms were assessed by Japanese Orthopedic Association (JOA) scores. Nonsurgical selected (JOA >or=13 patients). Seventy enrolled between 1995 2003. The follow-up rate 80.0%....

In Brief Study Design. vivo studies using a rat model were performed to determine the feasibility of microbubble-enhanced ultrasound gene transfer technique intervertebral disc. Objectives. 1) To establish this therapy for disc cells in without viral vectors and 2) estimate duration transgene expression vivo. Summary Background Data. Intervertebral degeneration associated spinal disorders remain formidable problem. Although approaches have been reported as having promising therapeutic...

Because the main pathology of cervical spondylotic myelopathy (CSM) is spinal cord damage due to compression, surgical treatment usually recommended improve patient symptoms and prevent exacerbation. However, lack clarity prognosis in cases that present with insignificant symptoms, particularly those mild CSM, lead one question veracity this course action. The purpose study was elucidate CSM without intervention by evaluation clinical MR imaging findings.Sixty (42 males 18 females, average...

In Brief Study Design. A prospective minimum 5-year follow-up study of the cervical spine in patients with rheumatoid arthritis (RA) initially without involvement. Objective. To clarify incidence and aggravation instabilities their predictive risk factors RA. Summary Background Data. Many reports have shown progression involvement However, few articles described comprehensive evaluation its prognostic factors. Methods. total 140 "definite" or "classical" RA were prospectively followed for...

Cyclic mechanical stress (CMS) was applied to cultured nucleus pulposus and anulus fibrosus cells, the production of inflammatory agents by these cells evaluated.To investigate involvement CMS in disc cells.It has been reported that affects degeneration disc. However, little is known about effect on both cell types vitro.Cells derived from Sprague-Dawley rat tails were with or without Flexercell Strain Unit (Flexcell International Corp., Hillsborough, NC) presence absence stimulus. Doses...

Clinical and imaging findings of patients diagnosed with pyogenic sacroiliitis were retrospectively analyzed.To characterize the clinical magnetic resonance features acute without usually known predisposing conditions to investigate diagnostic value in detecting early stages sacroiliitis.Pyogenic is relatively uncommon, accurate diagnosis frequently delayed due lack awareness by clinicians nonspecific presentation. There have been few reports that evaluated investigated capabilities...

The expression of cyclooxygenase-2 was studied immunohistologically in specimens from lumbar disc herniation. cultured cells also were examined to evaluate the significance cyclooxygenase-2, which might be involved pathogenesis herniation.To investigate whether herniation.Prostaglandin E2 is one most important mediators contributing pathogenetic components Cyclooxygenase-2, rate-limiting enzyme prostaglandin synthesis, has been identified and extensively investigated other inflammatory...

Object The pedicle screw has been reported to provide the strongest fixation for cervical spine, but there is a possibility of malpositioning screws, which may cause fatal complications such as vertebral artery and neural injuries. Using conventional freehand technique, between 6.7 29% screws have found be malpositioned. If an accurate entry point insertion trajectory through isthmus can maintained during surgery, safer should achieved. authors developed new method, called “CT cutout” report...

A prospective study.To identify outcomes of aged patients with lumbar spinal stenosis (LSS) treated conservatively and to examine factors that control the prognosis.There have been no reports evaluating conservative treatments for elderly LSS patients.A total 89 patients, 70 years age older, who underwent in-hospital treatment were included. The Japanese Orthopedic Association's score (JOA score) disturbance level activities daily living (ADL) used evaluation. Nerve involvement was...

Object Current surgical techniques for patients with pyogenic spondylitis (PS) and tuberculous (TS) are as follows: anterior debridement/decompression fusion bone autografts (A); fusion, followed by simultaneous or sequential posterior instrumentation (AP); instrumentation, (PA); decompression (P). In the present study authors compared, between disease types techniques, clinical radiological outcomes of surgery these patients. Methods Fifty-two were involved in study, comprising 25 PS 27 TS,...

A prospective long-term follow-up study of nonoperative treatment for lumbar spinal stenosis (LSS) and multivariable analysis the prognosis.To clarify outcomes LSS over a follow-up, to extrapolate factors relating prognosis treatment.The indicators remain controversial, few reports have evaluated its treatment, or extrapolated that aid prognosis.One hundred twenty patients who received inpatient were followed up 5 years longer. Patients' nerve involvement myelographic findings classified,...

Retrospective clinical analyses of patients with cervical spondylotic amyotrophy (CSA).To report the outcomes and predictive factors relating to prognosis in conservative surgical treatments for CSA.CSA is a entity characterized by muscle atrophy upper extremity without marked sensory disturbance or spastic tetraparesis. The indications for, CSA have not been clearly enunciated.Ninety were enrolled this study. All them initially received continuous traction 2 3 weeks as inpatients. If...

Molecular biological and immunohistological examinations.To clarify whether nondegenerated degenerated discs produce inflammatory agents such as prostaglandin (PG)E2, interleukin (IL)-6, IL-1β, tumor necrosis factor (TNF)α, which have been reported to play pivotal roles in lumbar disc diseases, the presence or absence of macrophages.A recent study discogenic low back pain might be caused by annular disruption followed vascularized granulation formation extending from outer layer annulus...