A5082886161- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Treatment of Major Depression
- Mechanical Circulatory Support Devices
- Liver Disease and Transplantation
- Palliative Care and End-of-Life Issues
- Dementia and Cognitive Impairment Research
- Mental Health Research Topics
- Geriatric Care and Nursing Homes
- Mental Health Treatment and Access
- Grief, Bereavement, and Mental Health
- Cardiac Structural Anomalies and Repair
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Sleep and related disorders
- Schizophrenia research and treatment
- Heart Failure Treatment and Management
- Family and Patient Care in Intensive Care Units
- Bipolar Disorder and Treatment
- Polyomavirus and related diseases
- Family Support in Illness
- Family Caregiving in Mental Illness
- Cardiac Arrest and Resuscitation
- Alcohol Consumption and Health Effects
University of Pittsburgh
2016-2025
University of Pittsburgh Medical Center
2015-2025
International Society for Heart and Lung Transplantation
2005-2024
IFC Research (United Kingdom)
2024
UPMC Health System
2000-2023
University of Kansas
2023
National Institute on Alcohol Abuse and Alcoholism
2023
Hudson Institute
2018-2020
John Wiley & Sons (United States)
2016-2020
Prevent Alzheimer’s Disease 2020
2020
ContextElderly patients with major depression are at high risk for recurrence, increased mortality, and chronic disability.ObjectiveTo determine the efficacy of maintenance nortriptyline hydrochloride interpersonal psychotherapy (IPT) in preventing recurrence depressive episodes older than 59 years.DesignA 2×2 randomized, double-blind, placebo-controlled clinical trial, stratified by therapist.SettingUniversity-based psychiatric research clinic.PatientsOf a total 187 recurrent nonpsychotic...
<h3>Context</h3> Cognitive impairment in late-life depression (LLD) is highly prevalent, disabling, poorly understood, and likely related to long-term outcome. <h3>Objectives</h3> To determine the characteristics determinants of neuropsychological functioning LLD. <h3>Design</h3> Cross-sectional study groups LLD patients control subjects. <h3>Setting</h3> Outpatient, university-based research clinic. <h3>Participants</h3> One hundred without dementia 60 years older who...
Objective Evidence concerning whether sleep disturbances in older adults predict mortality is mixed. However, data are limited to self-reported problems and may be confounded with other comorbidities. We examined electroencephalographic (EEG) parameters predicted survival time independently of known predictors all-cause mortality. Methods A total 185 healthy adults, primarily their 60s through 80s, no history mental illness, complaints, or current cognitive impairment, were enrolled one...
Background. Despite the impact of medical regimen nonadherence on health outcomes after organ transplantation, there is mixed and conflicting evidence regarding prevalence predictors posttransplant nonadherence. Clinicians require precise information rates in order to evaluate patients' risks for this problem. Methods. A total 147 studies kidney, heart, liver, pancreas/kidney-pancreas, or lung/heart-lung recipients published between 1981 2005 were included a meta-analysis. Average calculated...
Despite recommendations that patients be involved in the design and testing of health technologies, few reports describe how to involve systematic meaningful ways ensure applications are customized meet their needs. User-centered is an approach involves end users throughout development process so technologies support tasks, easy operate, value users. In this article, we provide overview user-centered use Pocket Personal Assistant for Tracking Health (Pocket PATH) illustrate these principles...
Elderly patients with major depression, including those having a first episode, are at high risk for recurrence of disability, and death.
For patients with end-stage liver disease, commonly used indices of nutritional status (ie, body weight and mass index) are often inflated because fluid overload ascites peripheral edema), this results in an underdiagnosis malnutrition. Because muscle is the largest protein reservoir body, estimate may be a more reliable valid status. Therefore, we pretransplant computed tomography data for 338 transplantation (LT) candidates to identify fat on basis specific abdominal transverse section...
Individuals use social media with varying quantity, emotional, and behavioral at- tachment that may have differential associations mental health outcomes. In this study, we sought to identify distinct patterns of (SMU) assess between those depression anxiety symptoms.In October 2014, a nationally-representative sample 1730 US adults ages 19 32 completed an online survey. Cluster analysis was used SMU. Depression were measured using respective 4-item Patient-Reported Outcome Measurement...
Live donor kidney transplantation is the best treatment option for most patients with late-stage chronic disease; however, rate of living donation has declined in United States. A consensus conference was held June 5–6, 2014 to identify practices and knowledge gaps pertaining live donation. Transplant professionals, patients, other key stakeholders discussed processes educating transplant candidates potential donors about donation; efficiencies evaluation process; disparities financial...
Black patients have a higher incidence of kidney failure but lower rate deceased- and living-donor transplantation compared with White patients, even after taking differences in comorbidities into account. We assessed whether social determinants health (e.g., demographics, cultural, psychosocial, knowledge factors) could account for race receiving transplantation.Via medical record review, we prospectively followed 1056 referred transplant (2010-2012), who completed an interview soon...
OBJECTIVE: Anxiety disorders are common in adults with depressive disorders, but several studies have suggested a relatively low prevalence of anxiety older individuals depression. This cross-sectional study measured current and lifetime rates associated clinical features depressed elderly patients. METHOD: History was assessed by using structured diagnostic instrument 182 subjects aged 60 seen primary care psychiatric settings. Associations between comorbid baseline characteristics were...
<h3>Background:</h3> Predictors of treatment response and recovery from depression in late life remain poorly understood. Previous studies have focused on a narrow range variables; namely, whether patients achieve or do not defined outcome time to the outcome. Whether vary their pathways toward those outcomes—and extent which such variation can be anticipated by patient characteristics prior treatment—has been empirically examined. <h3>Methods:</h3> Depression symptom levels were monitored...
For patients who receive a liver transplant (LTX) for alcoholic disease (ALD), investigators are focusing beyond survival to determine specific alcohol use outcomes. Studies suggest the of ranges from 8 22% first post-transplant year with cumulative rates reaching 30 40% by 5 years following transplantation. Yet while interested in determining and predictors use, only three studies since 1990 have been prospective. In 1998, we began prospective study post-LTX consumption ALD recipients using...