A5008484743- Organ Donation and Transplantation
- Renal Transplantation Outcomes and Treatments
- Renal and Vascular Pathologies
- Organ Transplantation Techniques and Outcomes
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Renal function and acid-base balance
- Neurological Complications and Syndromes
- Pharmacological Effects and Toxicity Studies
- Electrolyte and hormonal disorders
- Palliative Care and End-of-Life Issues
- Pregnancy and Medication Impact
- Muscle and Compartmental Disorders
- Central Venous Catheters and Hemodialysis
- Potassium and Related Disorders
- Acute Kidney Injury Research
- Blood donation and transfusion practices
- Erythropoietin and Anemia Treatment
- Grief, Bereavement, and Mental Health
- Vestibular and auditory disorders
- Renal Diseases and Glomerulopathies
- Immune Cell Function and Interaction
- Magnesium in Health and Disease
- Parathyroid Disorders and Treatments
- Transplantation: Methods and Outcomes
University of California, San Diego
2013-2024
University Hospital of Zurich
2024
Universität Innsbruck
2019
Med Center
2018
University of California San Diego Medical Center
1992-2017
University of Louisville
2004-2017
University of Toledo Medical Center
2014
University of Montana
2013
October 6 University
2011
UC San Diego Health System
2011
Objective This update of a 2008 guideline from the American Academy Otolaryngology-Head and Neck Surgery Foundation provides evidence-based recommendations to benign paroxysmal positional vertigo (BPPV), defined as disorder inner ear characterized by repeated episodes vertigo. Changes prior include consumer advocate added group; new evidence 2 clinical practice guidelines, 20 systematic reviews, 27 randomized controlled trials; enhanced emphasis on patient education shared decision making;...
Objective This update of a 2008 guideline from the American Academy Otolaryngology—Head and Neck Surgery Foundation provides evidence‐based recommendations to benign paroxysmal positional vertigo (BPPV), defined as disorder inner ear characterized by repeated episodes vertigo. Changes prior include consumer advocate added group; new evidence 2 clinical practice guidelines, 20 systematic reviews, 27 randomized controlled trials; enhanced emphasis on patient education shared decision making;...
Reported are the reduction of anti-HLA antibody levels and improvement transplant rates by intravenous immunoglobulin (IVIG) in a randomized, double-blind, placebo-controlled clinical trial. Between 1997 2000, total 101 adult patients with ESRD who were highly sensitized to HLA antigens (panel reactive [PRA] ≥50% monthly for 3 mo) enrolled onto an NIH-sponsored trial (IG02). Patients received IVIG or placebo. Subjects 2 g/kg 4 mo equivalent volume placebo additional infusions at 12 24 after...
Live donor kidney transplantation is the best treatment option for most patients with late-stage chronic disease; however, rate of living donation has declined in United States. A consensus conference was held June 5–6, 2014 to identify practices and knowledge gaps pertaining live donation. Transplant professionals, patients, other key stakeholders discussed processes educating transplant candidates potential donors about donation; efficiencies evaluation process; disparities financial...
Thymoglobulin, a rabbit anti-human thymocyte globulin, was compared with Atgam, horse globulin for the treatment of acute rejection after renal transplantation.A multicenter, double-blind, randomized trial enrollment stratification based on standardized histology (Banff grading) conducted. Subjects received 7-14 days Thymoglobulin (1.5 mg/kg/ day) or Atgam (15 mg/kg/day). The primary end point reversal (return serum creatinine level to below day 0 baseline value).A total 163 patients were...
Background. Intravenous gammaglobulin (IVIG) contains anti-idiotypic antibodies that are potent inhibitors of HLA-specific alloantibodies in vitro and vivo. In addition, highly HLA-allosensitized patients awaiting transplantation can have HLA alloantibody levels reduced dramatically by IVIG infusions, subsequent be accomplished successfully with a crossmatch-negative, histoincompatible organ. Methods. this study, we investigated the possible use to reduce donor-specific anti-HLA arising...
Modified Ivy bleeding time (template) and platelet aggregation to ADP, epinephrine, collagen were studied in 26 uremic patients who had not recently ingested anti-platelet drugs. Regardless of the aggregating agent used, abnormalities often mild, even with advanced uremia, frequently less severe than effects common The inhibition collagen-induced was significantly correlated both increased blood urea nitrogen. Platelet discriminative between clinically non-bleeding groups patients, but...
The American Academy of Otolaryngology—Head and Neck Surgery Foundation has published a supplement to this issue Otolaryngology–Head featuring the “Clinical Practice Guideline: Benign Paroxysmal Positional Vertigo (Update).” To assist in implementing guideline recommendations, article summarizes rationale, purpose, key action statements. 14 recommendations developed emphasize diagnostic accuracy efficiency, reducing inappropriate use vestibular suppressant medications, decreasing ancillary...
In light of continued uncertainty regarding postkidney donation medical, psychosocial and socioeconomic outcomes for traditional living donors especially meeting more relaxed acceptance criteria, a was held in September 2010 to (1) review limitations existing data on kidney donors; (2) assess define the need long-term follow-up (3) identify potential system requirements, infrastructure costs donor United States (4) explore practical options future development funding collection, metrics...
The specific mechanism whereby superficial nephron glomerular filtration rate (sngfr) is reduced after the administration of benzolamide, a carbonic anhydrase inhibitor with primary inhibitory effect in proximal tubule, have been examined by measuring pertinent pressures, flows, and permeabilities hydropenic Munich-Wistar rat, strain surface glomeruli. Because benzolamide decreases absolute reabsorptive rate, delivery tubular fluid to distal should be at least transiently increased may...
In chronic sodium depletion the glomerular filtration rate may be reduced, and alterations in proximal tubular function contribute to maintenance of antinatriuresis. Measurements were made by micropuncture technique superficial nephrons Munich-Wistar rat (a) determinants rate, (b) peritubular capillary hydrostatic oncotic pressure, (c) fractional absolute reabsorption both a control group (group 1, n = 12) chronically sodium-depleted rats 2, 12). Single nephron (sngfr) was 37.2±1.2 1...
De novo post donation renal diseases, such as glomerulonephritis or diabetic nephropathy, are infrequent and distinct from the loss of GFR at that all living kidney donors experience. Medical findings increase risks disease (e.g. microscopic hematuria,borderline hemoglobin A1C) often prompt donor refusal by centers. These risk factors part more comprehensive low end-stage (ESRD) diseases in general population equally relevant. Such data profile ages onset, rates progression, prevalence...
The Best Practice in Live Kidney Donation Consensus Conference held June of 2014 included the Practices Living Donor Education Workgroup, whose charge was to identify best practice strategies education living donors, community outreach initiatives, commercial media, solicitation, and state registries. workgroup's goal critical content include kidney donor methods deliver educational content. A detailed summary considerations regarding issues for potential donors is presented, including...
Background.Protein–energy wasting is common in patients on maintenance hemodialysis and strongly associated with poor quality of life mortality. However, clinical assessment protein–energy remains difficult. Predialysis creatinine levels are mortality risk but may be influenced by both muscle mass dialysis dose. This might overcome examining the rate rise between sessions.
Recent studies from the United States and Norway have suggested an unexpected 8- to 11-fold relative risk of ESRD after kidney donation, but a low long-term absolute risk. Abundant renal epidemiologic data predict that these underestimated The 1% lifetime post-donation in US study requires medical screening 96 100 candidates. This is particularly unlikely 30-35% candidates under age 35, half whose will occur 64. Many experts attributed increased risks loss GFR at which ultimately means...
Ten stable, normocalcemic renal transplant patients with good allograft function, hyperparathyroidism, and variable hypophosphatemia were treated for 2 to 9 months oral calcium carbonate replacement doses of vitamin D analogues. Parathyroid hormone levels (PTH) phosphate wasting not autonomous or fixed but decreased therapy. Although serum 1–25(OH)2D3 could be shown rise appropriately during therapy fall afterwards, a separate study in larger group showed no effect elevated parathyroid...