Neonatal abstinence syndrome (NAS) is a postnatal drug withdrawal primarily caused by maternal opiate use. No national estimates are available for the incidence of use at time delivery or NAS.To determine NAS and antepartum to characterize trends in health care expenditures associated with between 2000 2009.A retrospective, serial, cross-sectional analysis nationally representative sample newborns NAS. The Kids' Inpatient Database (KID) was used identify International Classification...

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The objective was to describe the characteristics of pediatric discharges associated with long-term mechanical ventilation (LTMV) compared those complex chronic conditions (CCCs), and evaluate trends over time in health care utilization for LTMV.The Kids' Inpatient Database, compiled by Agency Healthcare Research Quality, used. Routine newborn excluded. Discharges LTMV were identified using International Classification Diseases, Ninth Revision, code v46.1x CCCs 2006 simple regression χ(2)...

Objectives: Establishing protocols to wean mechanical ventilation and assess readiness for extubation, with the goal of minimizing morbidity associated extubation failure prolonged ventilation, have become increasingly important in contemporary PICUs. The aim this quality improvement initiative is establish a respiratory therapist–led daily spontaneous breathing trial protocol standardize assessment documentation our PICU. Design: A project. Setting: Single center, tertiary care Children’s...

The study objective was to describe characteristics and utilization patterns of tirzepatide users with type 2 diabetes (T2D) using the Healthcare Integrated Research Database in USA. Adults (≥18 years) included had T2D diagnosis; ≥1 claim (May 2022–January 2023; first date = index date); continuous medical pharmacy enrollment during 6-month baseline follow-up periods from date. Baseline demographics, clinical characteristics, dosing treatment were summarized descriptively. 15,665 patients...

To describe characteristics and overlap associated with various ventilator-associated infection criteria in the PICU.Retrospective observational study.A quaternary care children's hospital PICU.Children ventilated more than 48 hours, excluding patients tracheostomy.None.Ventilator-associated infection, including pneumonia, infection-related condition, tracheobronchitis, lower respiratory tract were defined according to from Centers for Disease Control Prevention or medical literature....

Diabetes has been identified as a high-risk comorbidity for COVID-19 hospitalization. We evaluated additional risk factors hospitalization and in-hospital mortality in nationwide US database. This retrospective study utilized the UnitedHealth Group Clinical Discovery Database (January 1, 2019–July 15, 2020) containing de-identified administrative claims, SARS-CoV-2 laboratory test results, inpatient admissions data. Logistic regression was used to understand among people with type 2 diabetes...

This prospective study aimed to describe the clinical course in terms of glycemic outcomes, body weight, and adverse events during first 12 weeks following a switch from glucagon-like peptide-1 receptor agonists (GLP-1 RAs) directly tirzepatide 5 mg.

<h3>Objective</h3>To determine whether hospital discharges for intussusception in children younger than 1 year have changed since the reintroduction of rotavirus vaccine United States.<h3>Design</h3>Serial cross-sectional analysis.<h3>Setting</h3>US hospitals.<h3>Participants</h3>Children with a discharge diagnosis identified Kids' Inpatient Database, series nationally representative data sets pediatric States 4 available years prior to (1997, 2000, 2003, and 2006) after (2009).<h3>Main...

Background: Cardiac tumors in children are rare. Of the cases reported literature, nearly all benign and managed conservatively. Methods: This is a retrospective, observational study of pediatric patients &lt;18 years who presented for surgical evaluation cardiac tumor, between 1969 2014 at tertiary care children’s hospital. Presentation, pathology, management, outcomes were evaluated. Results: Over last 45 years, 64 evaluated resection tumor. Rhabdomyoma was most common neoplasm (58%), 17%...

Thrombosis is a cause of morbidity in 4-15% children who undergo pediatric cardiac surgery. Data on how to prevent this complication are sorely needed. We aimed identify risk factors for thrombosis following surgery and determine if use low molecular weight heparin prophylaxis associated with reduction risk.Retrospective cohort study.Tertiary cardiovascular ICU.Patients underwent between June 2014 December 2015.None.Data from patients venous or arterial confirmed by radiologic studies were...

Newer incretin-based therapies for type 2 diabetes (T2D) have the potential to substantially reduce glycated hemoglobin (HbA1c) and weight with a low associated risk of hypoglycemia. This study aimed assess percentage participants randomized tirzepatide or comparator who achieved composite endpoint HbA1c ≤ 6.5% reduction ≥ 10% without hypoglycemia across prespecified baseline characteristics: T2D duration (≤ 5, > 5-10, 10 years), sex, 8.5% 8.5%), age (< 65 body mass index 30, 30 < 35, 35 kg/m

OBJECTIVE: Timely, high quality communication with families is essential to family-centered decision-making. Quality represented by widespread documentation of prognostic, goals-of-care conversations (PGOCC) in the pediatric intensive care unit (PICU) and should occur without variation patient characteristics. METHODS: Cohort included 645 PICU admissions top decile risk mortality on admission over six years. Electronic medical records were used determine PGOCC, diagnosis complex chronic...

Inpatient administrative data sources describe the care provided to hospitalized children. The Kids' Database (KID) provides nationally representative estimates, while Pediatric Health Information System (PHIS, a consortium of pediatric facilities) derives more detailed information from revenue codes. objective was contextualize diagnosis and procedure-based definition critical illness revenue-based definition; then compare it across hospitals with different levels care. This retrospective,...

: media-1vid110.1542/5789654354001PEDS-VA_2017-3082Video Abstract BACKGROUND: Management of pediatric emergencies is challenging for ambulatory providers because these rare events require preparation and planning tailored to the expected emergencies. The current recommendations in settings are based on 20-year-old survey data. We aimed objectively identify frequency etiology practices.We examined emergency medical services (EMS) runs originating from practices greater Indianapolis...

Objectives: Early extubation following pediatric cardiac surgery is common, but debate exists whether location affects outcome, with some centers performing routine early extubations in the operating room (odds ratio) and others ICU. We aimed to define practice variation across hospitals assess impact of on hospital length-of-stay other outcomes. Design: Secondary analysis Pediatric Cardiac Critical Care Consortium registry. Setting: Twenty-eight hospitals. Patients: Patients undergoing...

Guidelines recommend surgical antibiotic prophylaxis for clean-contaminated procedures but none clean procedures. The purpose of this study was to describe variations in outpatient urological at United States children's hospitals.Using the PHIS (Pediatric Health Information System®) database we performed a retrospective cohort patients younger than 18 years who underwent and/or from 2012 2014. We excluded those with concurrent nonurological or an abscess/infected wound. compared...

Background: Tracheostomy following congenital heart disease (CHD) surgery is a rare event and associated with significant mortality. Hospital survival has been reported from 20% to 40%. Late mortality for these patients not well characterized. Methods: We performed retrospective observational study of who had tracheostomy CHD (excluding isolated patent ductus arteriosus ligation) between January 2000 December 2013. Patients were categorized into single-ventricle or biventricular physiology...