A5066343086- Trauma and Emergency Care Studies
- Diversity and Career in Medicine
- Health and Medical Research Impacts
- Cardiac Arrest and Resuscitation
- Emergency and Acute Care Studies
- Injury Epidemiology and Prevention
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Policy and Management
- Gun Ownership and Violence Research
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Opioid Use Disorder Treatment
- Dental Education, Practice, Research
- Suicide and Self-Harm Studies
- Hip and Femur Fractures
- Trauma Management and Diagnosis
- Global Health Workforce Issues
- Traffic and Road Safety
- Abdominal Trauma and Injuries
- Pediatric Pain Management Techniques
- Urban Transport and Accessibility
- Autopsy Techniques and Outcomes
- Hospital Admissions and Outcomes
- Immune Cell Function and Interaction
- Traumatic Brain Injury Research
- Aortic aneurysm repair treatments
University of Utah
2021-2024
Primary Children's Hospital
2021-2023
East Kent Hospitals University NHS Foundation Trust
2023
Indiana University – Purdue University Indianapolis
2015-2020
Indiana University School of Medicine
2015-2020
Indiana University
2018-2020
Riley Hospital for Children
2016-2020
Indiana University Health
2015-2020
University School
2019-2020
Children's Hospital
2019
PURPOSE To conduct a pilot study to determine the safety, feasibility, and engraftment of haploidentical natural killer (NK) cell infusions after an immunosuppressive regimen in children with acute myeloid leukemia (AML). PATIENTS AND METHODS Ten patients (0.7 21 years old) who had completed chemotherapy were first complete remission AML enrolled on Pilot Study Haploidentical Natural Killer Cell Transplantation for Acute Myeloid Leukemia (NKAML) study. They received cyclophosphamide (60...
Abstract Background By the traditional definition of unintended weight loss, cachexia develops in ~80% patients with pancreatic ductal adenocarcinoma (PDAC). Here, we measure longitudinal body composition changes advanced PDAC undergoing 5‐fluorouracil, leucovorin, irinotecan, and oxaliplatin therapy. Methods We performed a retrospective review 53 on as first line therapy at Indiana University Hospital from July 2010 to August 2015. Demographic, clinical, survival data were collected. Body...
<h3>Abstract</h3> Consolidation therapies for children with intermediate- or high-risk acute myeloid leukemia (AML) are urgently needed to achieve higher cure rates while limiting therapy-related toxicities. We determined if adoptive transfer of natural killer (NK) cells from haploidentical immunoglobulin–like receptor (KIR)–human leukocyte antigen (HLA)-mismatched donors may prolong event-free survival in intermediate-risk AML who were first complete remission after chemotherapy. Patients...
BACKGROUND Hospital-based violence intervention programs (HVIP) aim to reduce violent-injury recidivism by providing intensive case management services high-risk patients who were violently injured. Although HVIP have been found effective at reducing recidivism, few studies sought identity how long their effects last. Additionally, prior limited the fact that typically rely on self-report or data within own healthcare system identify new injuries. Our was quantify long-term rate of...
Disparities in outcomes for uninsured trauma patients have been well documented. This study investigates whether failure to rescue (FTR) is a driver of mortality disparities after injury and treated at hospitals with large volume are more likely die complication.A retrospective cohort that analyzed patient records included the National Trauma Data Bank from years 2008 2010 was performed. Hierarchical logistic regression used examine probability insurance type would be associated...
The aim of this study was to compare the outcomes simultaneous and delayed implantation kidney grafts in combined liver-kidney transplantation (CLKT).Delayed function renal graft (DGF), which can result from hypotension pressor use related liver (LT), may cause worse CLKT.A total 130 CLKTs were performed at Indiana University between 2002 2015 studied an observational cohort study. All kidneys underwent continuous hypothermic pulsatile machine perfusion until transplant: 69 with (KT) (at...
Because of the unique physiology and comorbidities injured geriatric patients, specific interventions are needed to improve outcomes. The purpose this study was assess effect a change in triage criteria for patients evaluated at an American College Surgeons Level I trauma center.As October 1, 2013, all 70 years or older were mandated have highest-level activation upon emergency department (ED) arrival regardless mechanism injury. Patients admitted before that date designated as PRE; those...
Objective Determine drivers of academic productivity within U.S. departments surgery. Methods Eighty metrics for 3,850 faculty at the top 50 NIH-funded university- and 5 outstanding hospital-based surgical were collected using websites, Scopus, NIH RePORTER. Results Mean size was 76. Overall, there 35.3% assistant, 27.8% associate, 36.9% full professors. Women comprised 21.8%; 4.9% MD-PhDs 6.1% PhDs. By faculty-rank, median publications/citations were: 14/175, 39/649 full-professor, 97/2250....
BACKGROUND Psychological impairment among injury survivors is well documented. Little known about the prevalence of treatment psychological impairment, however. We aimed to determine proportion treated for depression and posttraumatic stress disorder (PTSD) in year after as potential barriers treatment. METHODS Adults (18 older) admitted a Level I trauma center with an severity score greater than 10 but without traumatic brain or spinal cord were eligible study inclusion. The Center...
Because Saudi Arabia (SA) has struggled with the burden of Road Traffic Injuries (RTIs) for decades, a new automated citations system was implemented in 2018 to improve compliance seatbelt and mobile phone laws. Therefore, purpose this study is evaluate impact on prevalence use among drivers Riyadh. This an observational conducted between 2017 2018. A Pre-Post evaluation employed determine camera detection use. Two research coordinators collected observations at several highways inner...
This descriptive epidemiology study describes trends in paediatric sports-related injuries resulting from 21 selected sports presenting to US emergency departments (EDs) over a 13-year period. The was retrospective using data the Consumer Product Safety Commission's National Electronic Injury Surveillance System (NEISS) for years 2001-2013. Inclusion criteria included people NEISS related one of and between ages 5 18 years. Frequencies linear regressions were calculated provided sample...
To determine the academic contribution as measured by number of publications, citations, and National Institutes Health (NIH) funding from PhD scientists in US departments surgery.The faculty working medical school clinical now exceeds basic science departments. The impact PhDs surgery has not been previously evaluated.Academic metrics for 3850 faculties at top 55 NIH-funded university hospital-based were collected using NIH RePORTER, Scopus, departmental websites.MD/PhDs had significantly...
Repair of abdominal aortic aneurysms (AAA) decreases the incidence rupture and death. In cancer patients, sarcopenia has been associated with increased surgical complications mortality. The impact on survival after AAA repair yet to be described.Patient demographic, laboratory, body composition measurements data were obtained from patients undergoing at Indiana University medical campus over a 5-year period. Univariate multivariate analyses performed identify factors overall survival....
BACKGROUND Injury can greatly impact patients' long-term quality of life. Resilience refers to an individual’s ability positively adapt after facing stress or trauma. The objective this study was examine the relationship between preinjury resiliency scores and life injury. METHODS Two hundred twenty-five adults admitted with Severity Score greater than 10 but without neurologic injury were included. 36-item Short Form administered at time admission repeated 1 month, 2 months, 4 12 months...
BACKGROUND Injured adolescents have a 56% increased risk of developing substance use disorder (SUD) within 3 years their injury. The transition from medical prescription opioid to nonmedical in adolescent trauma patients has not been longitudinally studied long-term. aim this study is describe 5-year patterns cohort injured as well the proportion experiencing overdose and SUD diagnoses. METHODS Our retrospective consisted 736 aged 12 18 who were admitted for 2011 2013. We examined up 5...
Despite being unable to purchase firearms directly, many adolescents have access guns, leading increased risk of injury and death. We sought determine if the National Instant Criminal Background Check System (NICS) changed adolescents' gun-carrying behavior.We performed a repeated cross-sectional study using Youth Risk Behavior Survey data from years 1993 2017. used survey-weighted multivariable logistic regression model NICS had an effect on adolescent gun carrying, controlling for state...