A5104293820- Nonmelanoma Skin Cancer Studies
- Cancer and Skin Lesions
- Immune Cell Function and Interaction
- Cutaneous lymphoproliferative disorders research
- T-cell and B-cell Immunology
- Cutaneous Melanoma Detection and Management
- Diversity and Career in Medicine
- Food Security and Health in Diverse Populations
- Reproductive System and Pregnancy
- Health and Medical Research Impacts
- International Student and Expatriate Challenges
- Neuroblastoma Research and Treatments
- Innovations in Medical Education
- International Business and FDI
- Family Business Performance and Succession
- Hair Growth and Disorders
- Cancer Diagnosis and Treatment
- CAR-T cell therapy research
- Hedgehog Signaling Pathway Studies
- Protein purification and stability
- 14-3-3 protein interactions
- History of Medicine Studies
- Reproductive Physiology in Livestock
- Economic Growth and Productivity
- Oral and gingival health research
St. Jude Children's Research Hospital
2009-2025
Harvard University
2021-2024
Dundalk Institute of Technology
2024
Brigham and Women's Hospital
2021-2024
Jiwaji University
2024
Case Western Reserve University
2021-2023
University School
2021-2023
University Hospitals of Cleveland
2022
Northeast Ohio Medical University
2021
IMSAR (United States)
2017
Killer cell Ig-like receptors (KIRs) on NK cells have been linked to a wide spectrum of health conditions such as chronic infections, autoimmune diseases, pregnancy complications, cancers, and transplant failures. A small subset effector memory T also expresses KIRs. In this study, we use modern analytic tools including genome-wide multiplex molecular, phenotypic, functional assays characterize the KIR(+) in human blood. We find that primarily reside CD56(+) population is distinctively...
Abstract Transcription factors are frequent cancer driver genes, exhibiting noted specificity based on the precise cell of origin. We demonstrate that ZIC1 exhibits loss-of-function (LOF) somatic events in group 4 (G4) medulloblastoma through recurrent point mutations, subchromosomal deletions and mono-allelic epigenetic repression (60% G4 medulloblastoma). In contrast, highly similar SHH distinct diametrically opposed gain-of-function mutations copy number gains (20% Overexpression...
<h3>Importance</h3> Tobacco 21 (T21) policies raise the minimum legal age to purchase tobacco from 18 years curb youth access products. While some studies have found that T21 is associated with reducing prevalence of use, little known about impact it may on different racial and ethnic identities. <h3>Objective</h3> To evaluate association policy high school use across sex, race, ethnicity. <h3>Design, Setting, Participants</h3> This survey study used representative data collected local...
Problem To overcome availability of the purified native zona pellucida ( ZP ) glycoproteins for immunocontraception, porcine 3, and 4 were expressed in E. coli . Method study Purified recombinant proteins characterized by SDS ‐ PAGE W estern blot, immunogenicity contraceptive efficacy determined F v B / J female mice. Results 3 with promiscuous T ‐cell epitope tetanus toxoid, incorporating bovine RN ase revealed ~44‐, ~49‐, ~53‐, ~55‐ kD a bands SDS‐PAGE Western respectively. Immunization...
Abstract Smooth muscle organs of the lower urinary tract comprise bladder detrusor and urethral wall, which have a reciprocal contractile relationship during urine storage micturition. As fills with urine, smooth cells (DSMCs) remain relaxed to accommodate increases in intravesical pressure while (USMCs) sustain tone occlude orifice, preventing leakage. While neither organ displays coordinated regular contractions as occurs small intestine, lymphatics or renal pelvis, they do exhibit...
Foramen Vesalius is a small, variable and an inconstant foramen located in the greater wing of sphenoid, anteromedial to ovale, middle cranial fossa.This also known as emissary sphenoidal it transmits small vein which drains Cavernous sinus.The importance this lies fact that infected thrombus from extracranial source may reach cavernous present study was undertaken observe incidence adult human crania north India.For purpose, 200 macerated skulls unknown age sex were observed.These obtained...
BACKGROUND Risk stratification can identify individuals in primary care settings who are at increased risk of developing melanoma. OBJECTIVE Converting and implementing a validated tool as patient self-administered tablet-based survey. METHODS Mackie was transformed into questionnaire. The questionnaire completed academic dermatologist practices by patients dermatologists revised to optimize sensitivity specificity using physician assessment gold standard. optimized survey administered...