Shaohua Zheng

ORCID: 0000-0002-4697-3778
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiac electrophysiology and arrhythmias
  • Multicomponent Synthesis of Heterocycles
  • Electrochemical Analysis and Applications
  • Electrochemical sensors and biosensors
  • Venous Thromboembolism Diagnosis and Management
  • Circular RNAs in diseases
  • Blood donation and transfusion practices
  • Reproductive tract infections research
  • Advanced Chemical Sensor Technologies
  • MicroRNA in disease regulation
  • Antifungal resistance and susceptibility
  • Microwave-Assisted Synthesis and Applications
  • Cardiac Imaging and Diagnostics
  • Anesthesia and Sedative Agents
  • Synthesis and biological activity
  • Extracellular vesicles in disease
  • Nail Diseases and Treatments
  • Heart Rate Variability and Autonomic Control
  • Analytical Chemistry and Sensors
  • Cardiac Arrhythmias and Treatments
  • Anesthesia and Pain Management
  • Anodic Oxide Films and Nanostructures
  • Acute Ischemic Stroke Management
  • Microbial Metabolic Engineering and Bioproduction

Wenzhou Medical University
2023

Dongyang People's Hospital
2023

First Affiliated Hospital of Xi'an Jiaotong University
2016-2022

Shaanxi Normal University
2018

China XD Group (China)
2018

Shandong University
2013-2015

Shandong Provincial QianFoShan Hospital
2013-2015

State Key Laboratory of Chemical Engineering
2015

East China University of Science and Technology
2015

Fujian Normal University
2012

Background A critical mechanism in atrial fibrillation (AF) is cardiac autonomic nerve remodeling (ANR). MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level. Numerous miRNAs involved diseases of nervous and cardiovascular systems. Objective We aimed to assess underlying role regulating ANR AF by right tachypacing (A-TP) canines. Methods Results Following 4-week A-TP, superior left ganglionated plexuses (SLGPs), which embedded fat pads...

10.1371/journal.pone.0122674 article EN cc-by PLoS ONE 2015-03-27

BackgroundThe potential mechanisms of microRNA-1 (miR-1) in the electrical remodeling atrial fibrillation remain unclear. The purpose this study was to evaluate effects miR-1 on effective refractory period (AERP) a right tachypacing model and elucidate mechanisms. Methods ResultsQRT-PCR western blot were used detect expression miR-1, KCNE1, KCNB2 genes after 1-week New Zealand white rabbits. AERP measured using programmable multichannel stimulator, induced by burst stimulation vivo. slowly...

10.1371/journal.pone.0085639 article EN cc-by PLoS ONE 2013-12-30

The remarkable activation of stable titanocene dichloride (Cp2TiCl2) was achieved using N-donor ligand urea in an alcoholic solvent, leading to the formation a Ti(iv) species [(MeO)2Ti(NHCONH2)]+, existence which verified by ESI-MS, ESI-MS/MS, and NMR. Catalyzed newly formed species, myriad 3,4-dihydropyrimidin-2-(1H)-ones were produced via three-component Biginelli reaction. Further mechanistic investigation indicated that reaction had taken place imine route.

10.1039/c8ra01208c article EN cc-by RSC Advances 2018-01-01

Background No evidence has been presented to show whether autonomic neural remodeling occurs in pulmonary vein‐left atrium (PV‐LA) junction and what an important role it may play AF. This study aims find out these issues a prolonged rapid atrial pacing canine model. Methods Twelve healthy mongrel dogs were randomly divided into two groups, six each: the paced group underwent right at 400 beats per minute for 4 weeks, control was not paced. The effective refractory period (ERP) of left...

10.1111/pace.12338 article EN Pacing and Clinical Electrophysiology 2013-12-20

A sensitive electrochemical sensor based on immobilized multiwalled carbon nanotubes (MWCNTs) and 1-butyl-3-methylimidazolium hexafluorophosphate (BMIM·PF6) a glassy electrode (GCE) for o-sec-butylphenol (osBP) was proposed. The electro-oxidation behavior studied, the experimental conditions were optimized kinetic parameters calculated. results indicated that this has advantages of fast electron-transfer rate, minimal fouling electrodes, high sensitivity stability o-sec-butylphenol. Upon...

10.1039/c2an35557d article EN The Analyst 2012-01-01

A rapid analytical method based on online solid-phase extraction with high-performance liquid chromatography and mass spectrometry has been established applied to the determination of tannin compounds that may cause adverse effects in traditional Chinese medicine injections. Different sorbents have compared elution buffer was optimized. The performance verified by evaluation recovery (≥40%), repeatability (RSD ≤ 6%), linearity (r(2) ≥ 0.993), limit quantification (≤0.35 μg/mL). Five...

10.1002/jssc.201501037 article EN Journal of Separation Science 2016-01-06

Abstract A growing number of reports have shown that oxidative stress is an important contributing factor for atrial fibrillation (AF). The identification stress-related blood biomarkers patients with AF has great significance the early prevention and treatment AF. purpose this study was to illuminate relationship several markers This enrolled hospitalized from January 2018 December 2020 at Department Cardiology in a tertiary center east China.Clinical data, emphasis on biomarkers, were...

10.21203/rs.3.rs-3063179/v1 preprint EN cc-by Research Square (Research Square) 2023-06-30

Objective To compare the blood-saving effect when acute hypervolemic hemodilution (AHH) was performed with hydroxyethyl starch (HES) 130/0.4 dissolved in electrolyte injection (HES-E) and HES sodium chloride (HES-NaCl). Methods Thirty patients of both sexes, aged 18-60 yr, American Society Anesthesiologists physical statusⅠ or Ⅱ, body mass index 18-25 kg/m2, hemoglobin (Hb)>100 g/L, hematocrit (Hct)> 35%, scheduled for elective abdominal operations under general anesthesia, were...

10.3760/cma.j.issn.0254-1416.2016.07.016 article EN Zhonghua mazuixue zazhi 2016-07-20

This study aimed to observe the effect of internship in a pre-anesthetic clinic on teaching quality pre-anesthesia evaluation for undergraduates.A total 120 undergraduates from July 2017 2018 anesthesia department our hospital were randomly divided into two groups: group (n = 60) and traditional 60). The knowledge chapters was evaluated between groups undergraduates.There no significant differences demographic information groups. scores case analysis theoretical test significantly higher...

10.17245/jdapm.2021.21.3.207 article EN Journal of Dental Anesthesia and Pain Medicine 2021-01-01
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