<sec> <title>BACKGROUND</title> Gender plays a role healthcare simulation in multiple areas: communication, specific treatments, outcomes, anatomy, biases, and others. Often female simulators virtual patient avatars are only skin deep, not considering the vast physiological differences at play between biological sex of chosen gender associated state patient. It is important that as evolves, communicated taught to prospective students variety experiences. </sec> <title>OBJECTIVE</title> We...

Background: There is a limitation in understanding complete cardiopulmonary function during moments of exhaustive exercise due to invasive measurement techniques. We asked how perturbed times different age cohorts: 6–11 and 11–18. sought broadly analyze oxidative stress differ across cohorts. Methods: present whole-body physiology model that connects the nervous, cardiovascular, respiratory, oxygen transport binding systems. connect these models using lumped parameter representation...

This article provides models and code for numerically simulating muscle-fluid-structure interactions (FSIs). work was presented as part of the symposium on Leading Students Faculty to Quantitative Biology through Active Learning at society-wide meeting Society Integrative Comparative in 2015. Muscle mechanics simple mathematical describe forces generated by muscular contractions are introduced most biomechanics physiology courses. Often, however, derived simplifying cases such isometric or...

Using virtual patients, facilitated by natural language processing, provides a valuable educational experience for learners. Generating large, varied sample of realistic and appropriate responses patients is challenging. Artificial intelligence (AI) programs can be viable source these responses, but their utility this purpose has not been explored.

Sepsis is a debilitating condition associated with high mortality rate that greatly strains hospital resources. Though advances have been made in improving sepsis diagnosis and treatment, our understanding of the disease far from complete. Mathematical modeling has potential to explore underlying biological mechanisms patient phenotypes contribute variability septic outcomes. We developed comprehensive, whole-body mathematical model pathophysiology using BioGears Engine, robust open-source...

Opioid use in the United States and abroad is an endemic part of society with yearly increases overdose rates deaths. In response, safe effective reversal agent, naloxone, being fielded used by emergency medical technicians at a greater rate. There evidence that repeated dosing naloxone nasal spray becoming more common. Despite this we lack guidelines as function amount opiate patient has taken.

We have created a model of systemic burn pathophysiology by incorporating mathematical acute inflammation within the BioGears Engine. This produces outputs consistent with burns varying severities and leverages existing functionality to simulate effect treatment on virtual patient outcome. The performs well for standard resuscitation scenarios we thus expect it be useful educational training purposes.

BioGears is an open-source, lumped parameter, full-body human physiology engine. Its purpose to provide realistic and comprehensive simulations for medical training, research, education. incorporates a physiologically based pharmacokinetic/pharmacodynamic (PK/PD) model that designed be applicable diversity of drug classes patients extensible future drugs. In addition, also supports interactions with various patient insults interventions allowing research framework accurate dose-patient...

BioGears is an open source, extensible human physiology computational engine that designed to enhance medical education, research, and training technologies.BioGears primarily written in C++ uses electric circuit analog characterize the fluid dynamics of cardiopulmonary system.As requirements become more complex, there a need supplement traditional simulators with simulations.To this end, provides extensive number validated injury models related interventions may be applied simulated...

<sec> <title>BACKGROUND</title> Misidentification of dermatologic manifestations systemic infection can lead to life-threatening developments including sepsis. </sec> <title>OBJECTIVE</title> Training medical providers accurately identify and respond infections using simulation could reduce these rates. Moulage are static require a manual “scene change” during scenarios. <title>METHODS</title> A high-fidelity, automated physiology-driven dynamic model was developed the Modular Healthcare...

Abstract Background Applied Research Associates (ARA) and the United States Army Institute of Surgical (USAISR) have been developing a tablet-based simulation environment for burn wound assessment shock resuscitation. This application aims to supplement current gold standard in care education, Advanced Burn Life Support (ABLS) curriculum. Results Subject matter experts validate total body surface area (TBSA) identification analysis show that visual fidelity tablet virtual patients is...

<h3>Background</h3> Communication aids can facilitate advance care planning (ACP) conversations. The vignette technique involves using scenarios of sensitive clinical circumstances to explore research participants' perspectives. Its use in ACP remains unexplored. <h3>Aim</h3> To examine the discussions with cancer patients and their caregivers. <h3>Methods</h3> Secondary analysis qualitative methods on data from three previous studies examining patients' caregivers' perspectives...

Heart failure (HF) is associated with impaired renal function and sodium retention. This has been attributed to systemic hemodynamic changes: forward causing decreased artery pressure (RAP) backward venous congestion increased (RVP). In this work we investigate how changes in RAP RVP separately combination affect reabsorptive function. We use a published well-characterized mathematical kidney model incorporating superficial deep nephrons hemodynamics (including myogenic response, MR,...

Abstract Opioid use in the United States and abroad is an endemic part of culture with yearly increases overdose rates deaths. As incidence increases, safe effective reversal agent, naloxone, form a nasal rescue spray being fielded used by emergency medical technicians (EMTs) at greater rate. Despite advances deployment these products, deaths are continuing to increase. There evidence that repeated dosing naloxone (such as Narcan) becoming more common due amount type opiate abused. benefits...

<sec> <title>BACKGROUND</title> Using virtual patients, facilitated by natural language processing, provides a valuable educational experience for learners. Generating large, varied sample of realistic and appropriate responses patients is challenging. Artificial intelligence (AI) programs can be viable source these responses, but their utility this purpose has not been explored. </sec> <title>OBJECTIVE</title> In study, we explored the effectiveness generative AI (ChatGPT) in developing...

<title>Abstract</title> Opioid use in the United States and abroad is an endemic part of culture with yearly increases overdose rates deaths. As incidence increases, safe effective reversal agent, naloxone, form a nasal rescue spray being fielded used by emergency medical technicians (EMTs) at greater rate. Despite advances deployment these products, deaths are continuing to increase. There evidence that repeated dosing naloxone (such as Narcan) becoming more common due amount type opiate...

Background In oncology, informal caregivers often partake in patient-medical consultations and treatment decision making, yet little is known about their views on advance care planning (ACP). Understanding what want to communicate with cancer patients health workers, regarding wishes goals, may complement potentially further the development of an appropriate ACP framework integrative centre. Aim To understand caregivers' perspectives relation potential limitations, barriers, facilitators...