A5103963973- Burn Injury Management and Outcomes
- Characterization and Applications of Magnetic Nanoparticles
- Wound Healing and Treatments
- Disaster Response and Management
- Microfluidic and Capillary Electrophoresis Applications
- Cardiac Arrest and Resuscitation
- Electrohydrodynamics and Fluid Dynamics
- Traumatic Brain Injury and Neurovascular Disturbances
- Injury Epidemiology and Prevention
- Advanced MRI Techniques and Applications
- Micro and Nano Robotics
- Fluid Dynamics and Vibration Analysis
- Lattice Boltzmann Simulation Studies
- Fluid Dynamics and Turbulent Flows
- Cardiac, Anesthesia and Surgical Outcomes
- Knee injuries and reconstruction techniques
- Colorectal Cancer Screening and Detection
- Intensive Care Unit Cognitive Disorders
- Art Therapy and Mental Health
- Extracellular vesicles in disease
- Muscle and Compartmental Disorders
- Engineering Education and Pedagogy
- Mechanical Circulatory Support Devices
- Spectroscopy and Chemometric Analyses
- Clinical Reasoning and Diagnostic Skills
United States Army Institute of Surgical Research
2020-2025
Carolinas Medical Center
2025
Brooke Army Medical Center
2020-2024
Joint Base San Antonio
2020-2024
OrthoCarolina
2024
Wilford Hall Ambulatory Surgical Center
2022
Baylor University
2021
Virginia Tech
2006-2021
Cornell Lab of Ornithology
2021
Cornell University
2021
Traumatic brain injury resulting from an explosive blast is one of the most serious wounds suffered by warfighters, yet effects overpressure directly impacting head are poorly understood. We developed a rodent model direct cranial (dcBI), in which could be delivered exclusively to head, precluding indirect via thoracic transmission wave. constructed and validated Cranium Only Blast Injury Apparatus (COBIA) deliver overpressures generated detonating .22 caliber cartridges smokeless powder....
Background: Loss of motion and arthrofibrosis after anterior cruciate ligament (ACL) reconstruction (ACLR) can be devastating complications for athletes. The cellular molecular pathogenesis is poorly understood, limiting prevention treatment options. Synovial inflammation may contribute to post-ACLR arthrofibrosis. Hypothesis: Higher synovial immune cell infiltration inflammatory/catabolic gene expression patterns at the time ACLR would correlate with poorer motion-related outcomes. Study...
Abstract Prospective discovery of molecular glues degraders for a specific therapeutic target protein interest is an emerging strategy in drug discovery. Modification pre-existing ligands with fragments that can alter the surface lead to creation novel compounds (‘’targeted glues’’) able induce neo-interactions between and E3 ligase, resulting targeted degradation. By screening library potential BRD9 glue compounds, we have discovered potent selective, reversibly covalent degrader, AMPTX-1 ....
Abstract Introduction Psychosocial distress is common among burn survivors, and early detection crucial for timely intervention referrals. Many studies highlight the benefits of psychological support during hospitalization, yet numerous centers lack embedded behavioral health services. Additionally, well-being non-burn patients (e.g., those with soft tissue infections or other skin conditions) treated in understudied. Reliance on psychosocial screening outpatient visits may miss symptoms...
Abstract Though coffee was traditionally grown as an understory crop beneath mature trees (i.e. ‘shade‐grown’ coffee), most farms have been converted to full‐sun monocultures over time, which fail support ecosystem services or biodiversity. The conversion from shade‐ sun‐grown has prompted the development of environmentally focused certifications, such Smithsonian Bird Friendly ® coffee, one market‐based strategy incentivize sustainable production coffee. Birdwatchers, there are 45 million...
Using focused shadowgraphs, we investigate steady flows of a magnetically non-susceptible fluid interacting with ferrofluid aggregates comprised superparamagnetic nanoparticles. The aggregate is retained at specific site within the flow channel using two different applied magnetic fields. bulk induces shear stresses on aggregate, which give rise to development interfacial disturbances, leading Kelvin-Helmholtz (K-H) instabilities and shedding structures. Herein, effects Reynolds number,...
Gluteal Compartment Syndrome (GCS) is a rare subtype of acute compartment syndrome (ACS), complex to diagnose and potentially fatal if left untreated. The incidence ACS estimated be 7.3 per 100,000 in males 0.7 females [1–3]. Given its occurrence, the GCS not well reported. In case GCS, most common etiologies are surgical positioning, prolonged immobilization secondary substance use or loss consciousness, traumatic injury. Clinical findings pulselessness, pallor, parasthesia, paralysis,...
Abstract Background Applied Research Associates (ARA) and the United States Army Institute of Surgical (USAISR) have been developing a tablet-based simulation environment for burn wound assessment shock resuscitation. This application aims to supplement current gold standard in care education, Advanced Burn Life Support (ABLS) curriculum. Results Subject matter experts validate total body surface area (TBSA) identification analysis show that visual fidelity tablet virtual patients is...
The physics of steady and pulsatile flows laden with superparamagnetic nanoparticles in a square channel accumulating under the influence 0.5 Tesla permanent magnet are studied by means focused shadowgraphs. accumulation these nanoscale particles is explored as functions flow type (steady unsteady) (injected from top versus bottom channel). Ferrofluid accumulated injection streakline that enters test section upstream magnet, where an aggregate forms. interfacial phenomena resulting...
Ferrohydrodynamics research has been approached predominantly from either numerical or basic experimental techniques. However, to date, these techniques have limited ultrasonic point measurements shadowgraphs due the opacity of ferrofluids. As a result, complete dynamics many ferrohydrodynamics flows remained unexplored. In this work, Time Resolved Digital Particle Image Velocimetry (TRDPIV) is employed fully resolve dynamic interaction ferrofluid aggregates with bulk nonmagnetic fluids....
Abstract NOTE: The first page of text has been automatically extracted and included below in lieu an abstract Using Fluid Mechanics Research Examples to Enhance Stimulate Undergraduate Engineering Education Introduction Approximately 62% the undergraduate students who graduated 2000 with engineering B.S. United States received their degree from I II institutions. 1 Although these universities successfully recruit undergraduates by proudly displaying research infrastructure state-of-the-art...
Abstract Introduction Nutrition is a core component of care for the critically ill burn patient. The Society Critical Care Medicine recommends initiating enteral nutrition (EN) within 4–6 hours injury patients, while simultaneously recommending waiting until hemodynamic stability achieved critical patients. goal this analysis was to evaluate tolerance EN during periods different pressor requirements and lactate levels. Methods We performed retrospective evaluation on all patients admitted...
Abstract Introduction Patients who require extracorporeal membrane oxygenation (ECMO) have a very high mortality if they develop septic shock. Extracorporeal blood purification has been studied as an adjunct to antimicrobials but yielded mixed or even disappointing results. The Seraph-100 Microbind Affinity Blood Filter (ExThera Medical Corporation, Martinez, CA) is currently undergoing clinical trials. filter consists of polyethylene beads, coated in heparin sulfate, that irreversibly binds...