A5079444927- Colorectal Cancer Screening and Detection
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Global Cancer Incidence and Screening
- Colorectal Cancer Surgical Treatments
- Diverticular Disease and Complications
- Pancreatic and Hepatic Oncology Research
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Esophageal Cancer Research and Treatment
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Colorectal Cancer Treatments and Studies
- Gastroesophageal reflux and treatments
- Gastrointestinal disorders and treatments
- Colorectal and Anal Carcinomas
- Health Systems, Economic Evaluations, Quality of Life
- Healthcare Policy and Management
- Cancer Genomics and Diagnostics
- Microscopic Colitis
- Multiple and Secondary Primary Cancers
- Neonatal Respiratory Health Research
- Eosinophilic Esophagitis
- Economic and Financial Impacts of Cancer
- Food Security and Health in Diverse Populations
University of California, San Diego
2016-2025
VA San Diego Healthcare System
2016-2025
UC San Diego Health System
2014-2024
Moores Cancer Center
2015-2024
Durham University
2019-2024
CancerCare Manitoba
2024
University of Manitoba
2024
St. Michael's Hospital
2024
Unity Health Toronto
2024
University of Toronto
2022-2024
Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria assessment the identification of who are carriers pathogenic genetic variants. The NCCN Guidelines Genetic/Familial High-Risk Assessment: Colorectal provide recommendations management patients high-risk colorectal syndromes. These Insights focus on evaluation Lynch syndrome considerations use multigene testing in
Colorectal cancer (CRC) incidence and mortality are rising among young adults. Our aim was to contrast the relative of CRC other common cancers adults in USA. We used Surveillance, Epidemiology, End Results registry data compare site-specific age-specific incident rates for younger than age 50. summarized extracted data, both overall, stratified by sex. found third leading cause death 50, after breast lung (1.67 cases per 100,000). Among women, fourth (1.51 men, second (1.82 most men women...
This is a focused update highlighting the most current NCCN Guidelines for diagnosis and management of Lynch syndrome. syndrome common cause hereditary colorectal cancer, usually resulting from germline mutation in 1 4 DNA mismatch repair genes (MLH1, MSH2, MSH6, or PMS2), deletions EPCAM promoter. Patients with are at an increased lifetime risk, compared general population, endometrial other cancers, including stomach ovary. As 2016, panel recommends screening all patients cancer provides...
<h3>Importance</h3> Colorectal cancer (CRC) screening saves lives, but participation rates are low among underserved populations. Knowledge on effective approaches for the underserved, including best test type to offer, is limited. <h3>Objective</h3> To determine (1) if organized mailed outreach boosts CRC compared with usual care and (2) FIT superior colonoscopy in an population. <h3>Design, Setting, Participants</h3> We identified uninsured patients, not up date screening, age 54 64 years,...
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Colorectal provide recommendations the management of patients with high-risk syndromes associated an increased risk colorectal cancer (CRC). Panel meets at least annually to assess comments from reviewers within their institutions, examine relevant data, and reevaluate update recommendations. These Insights focus on genes newly CRC multigene panels, evidence, currently recommended strategies.
Background & AimsColorectal cancer (CRC) incidence and mortality are increasing among persons younger than 50 years old in the United States, but risk factors associated with early-onset CRC (EOCRC) have not been widely studied.MethodsWe conducted a case-control study of US veterans 18 to 49 who underwent colonoscopy examinations from 1999 through 2014. EOCRC cases were identified national registry; free at their baseline 3 follow-up as controls. We collected data on age, sex,...
Colonoscopy with polypectomy reduces the incidence of and mortality from colorectal cancer (CRC).1,2 It is cornerstone effective prevention.3 The National Polyp Study showed that removal adenomas during colonoscopy associated a reduction in CRC by up to 50% relative population controls.1,2 lifetime risk develop United States approximately 4.3%, 90% cases occurring after age 50 years.4 recent reductions have been largely attributed widespread uptake screening polypectomy.5 techniques outcomes...
Colonoscopy is performed routinely for colorectal cancer (CRC) screening, follow-up of other abnormal screening tests, workup signs and symptoms gastrointestinal disease, surveillance after CRC polyp removal. Post procedure, colonoscopists are expected to provide recommendations patients referring physicians. Recommendations normal colonoscopy among individuals age-eligible post-polypectomy all with polyps the most common clinical scenarios requiring guidance.1 Risk metachronous advanced...
Colorectal cancer is the third most diagnosed in adults United States. Early detection could prevent more than 90% of colorectal cancer-related deaths, yet one screening-eligible population not up to date with screening despite multiple available tests. A blood-based test has potential improve adherence, detect earlier, and reduce mortality.
Identifying individuals with hereditary syndromes allows for timely cancer surveillance, opportunities risk reduction, and syndrome-specific management. Establishing criteria assessment the identification of who are carriers pathogenic genetic variants. The NCCN Guidelines Genetic/Familial High-Risk Assessment: Colorectal provides recommendations management patients at or diagnosed high-risk colorectal syndromes. panel meets annually to evaluate update their based on clinical expertise new...
is the most common cause of infection-associated cancer worldwide. We aimed to evaluate impact H. pylori infection and treatment on colorectal (CRC) incidence mortality.
Hepatocellular carcinoma (HCC) surveillance is underutilized among patients with cirrhosis. Understanding which steps in the process are not being conducted essential for designing effective interventions to improve rates. The aim of our study was characterize reasons failure HCC a cohort cirrhotic HCC. We retrospective diagnosed at large urban safety-net hospital between 2005 and 2011. Patients were characterized by receipt over two-year period before diagnosis. Among without surveillance,...
The NCCN Guidelines for Colorectal Cancer (CRC) Screening outline various screening modalities as well recommended strategies individuals at average or increased-risk of developing sporadic CRC. panel meets least annually to review comments from reviewers within their institutions, examine relevant data, and reevaluate update recommendations. These Insights summarize 2018 updates the Guidelines, with a primary focus on used screen average-risk