Jennifer Greco
A5037581593- Stellar, planetary, and galactic studies
- Astro and Planetary Science
- Astronomy and Astrophysical Research
- Planetary Science and Exploration
- Astrophysics and Star Formation Studies
- Isotope Analysis in Ecology
- Astronomical Observations and Instrumentation
- Gamma-ray bursts and supernovae
- Space Exploration and Technology
- Genetic Associations and Epidemiology
- Primary Care and Health Outcomes
- Substance Abuse Treatment and Outcomes
- Glaucoma and retinal disorders
- Diabetes and associated disorders
- Ophthalmology and Visual Impairment Studies
- Nuclear physics research studies
- Aortic aneurysm repair treatments
- Lipoproteins and Cardiovascular Health
- Suicide and Self-Harm Studies
- Health Policy Implementation Science
- Molecular Spectroscopy and Structure
- Pancreatic function and diabetes
- Chronic Kidney Disease and Diabetes
- Diabetes Treatment and Management
- Opioid Use Disorder Treatment
VA Boston Healthcare System
2022-2024
Geriatric Research Education and Clinical Center
2024
Boston University
2024
Harvard University
2024
Sioux Falls VA Health Care System
2024
VA Office of Research and Development
2019-2023
University of Toledo
2016-2022
Swedish Collegium for Advanced Study
2022
Uppsala University
2022
Durham VA Health Care System
2021
Coronavirus disease 2019 (COVID-19) confers significant risk of acute kidney injury (AKI). Patients with COVID-19 AKI have high mortality rates.Individuals African ancestry 2 copies apolipoprotein L1 (APOL1) variants G1 or G2 (high-risk group) significantly increased rates disease. We tested the hypothesis that APOL1 high-risk group is associated a higher-risk COVID-19-associated and death.This retrospective cohort study included 990 participants enrolled in Million Veteran Program who were...
Importance Recently, the US Food and Drug Administration gave premarketing approval to an algorithm based on its purported ability identify individuals at genetic risk for opioid use disorder (OUD). However, clinical utility of candidate variants included in has not been independently demonstrated. Objective To assess 15 from intended predict OUD risk. Design, Setting, Participants This case-control study examined association with using electronic health record data December 20, 1992,...
We use the AllWISE Data Release to continue our search for WISE-detected motions. In this paper, we publish another 27,846 motion objects, bringing total number 48,000 when objects found during original survey are included. list, along with lists of confirmed WISE-based from recent papers by Luhman and Schneider et al. candidate paper Gagne widely separated, common-proper-motion systems. identify 1,039 such All further analyzed using color-color color-mag plots provide possible...
The Wide-field Infrared Survey Explorer (WISE) was reactivated in December of 2013 (NEOWISE) to search for potentially hazardous near-Earth objects. We have conducted a survey using the first sky pass NEOWISE data and AllWISE catalog identify nearby stars brown dwarfs with large proper motions ($\mu_{\rm total}$ $\gtrsim$ 250 mas yr$^{-1}$). A total 20,548 high motion objects were identified, 1,006 which are new discoveries. This has uncovered significantly larger sample fainter (W2...
ι Ori is a well-studied massive binary consisting of an O9 III + B1 III/IV star. Due to its high eccentricity (e = 0.764) and short orbital period (Porb 29.133 76 d), it has been considered be good candidate show evidence tidal effects; however, none have previously identified. Using photometry from the BRIght Target Explorer (BRITE)-Constellation space mission, we confirmed existence distortions through presence heartbeat signal at periastron. We combine spectroscopic light-curve analyses...
We present the discoveries of WISEA J041451.67-585456.7 and J181006.18-101000.5, two low-temperature (1200$-$1400 K), high proper motion T-type subdwarfs. Both objects were discovered via their ($>$0.5 arcsec yr$^{-1}$); J181006.18-101000.5 as part NEOWISE survey citizen science project Backyard Worlds; Planet 9. have confirmed both brown dwarfs with follow-up near-infrared spectroscopy. Their spectra colors are unique amongst known dwarfs, some consistent L-type other resembling those...
Abstract Background Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are associated with self-reported problems cognition as well risk for Alzheimer’s disease related dementias (ADRD). Overlapping symptom profiles observed in cognitive disorders, psychiatric environmental exposures (e.g., head injury) can complicate the detection of early signs ADRD. The interplay between PTSD, injury, subjective (self-reported) concerns genetic ADRD is also not understood, particularly...
Elevated Lipoprotein(a) [Lp(a)] is a causal risk factor for atherosclerotic cardiovascular disease, but the mechanisms of are debated. Studies have found inconsistent associations between Lp(a) and measurements atherosclerosis. We aimed to assess relationship Lp(a), low-density lipoprotein cholesterol (LDL-C) coronary artery plaque severity.
Background: Familial hypercholesterolemia (FH) is characterized by inherited high levels of LDL-C (low-density lipoprotein cholesterol) and premature coronary heart disease. Over a thousand low-frequency variants in LDLR, APOB, PCSK9 have been implicated FH, but few examined at the population level. We aim to estimate phenotypic effects subset FH on clinical outcomes among 331 107 multiethnic participants. Methods: individual collective association between putatively pathogenic included...
Abstract With an increased focus on the observing and modeling of mini-Neptunes, there comes a need to better understand tools we use model their atmospheres. In this Paper, present protocol for Comparing Atmospheric Models Extrasolar Mini-Neptunes Building Envisioning Retrievals Transits, CAMEMBERT, project, intercomparison general circulation models (GCMs) used by exoplanetary science community simulate atmospheres mini-Neptunes. We two targets well studied both observationally...
Abstract The late-type Be star β CMi is remarkably stable compared to other stars that have been studied. This has led a realistic model of the outflowing disk by Klement et al. These results showed likely truncated at finite radius from star, which suggest evidence for an unseen binary companion in orbit. Here we report on analysis Ritter Observatory spectroscopic archive search elusive companion. We detect periodic Doppler shifts wings H α line with period 170 days and amplitude 2.25 km s...
To characterize high type 1 diabetes (T1D) genetic risk in a population where 2 (T2D) predominates.
We present low-resolution near-infrared spectra of discoveries from an all-sky proper motion search conducted using multi-epoch data the Wide-field Infrared Survey Explorer. Using NEOWISE, along with AllWISE catalog, Schneider et al. (2016) survey to for nearby objects high motions. Here, we a follow-up spectroscopic 65 their discoveries, which focused primarily on potentially (d < 25 pc), candidate late-type brown dwarfs (>L7), and subdwarf candidates. found 31 new M dwarfs, 18 L 11 T...
Abstract The Phenome-Wide Association Study (PheWAS) is increasingly used to broadly screen for potential treatment effects, e.g., IL6R variant as a proxy antagonists. This approach offers an opportunity address the limited power in clinical trials study differential effects across patient subgroups. However, methods exist efficiently test differences subgroups thousands of multiple comparisons generated part PheWAS. In this study, we developed that maximizes heterogeneous genotype–phenotype...
Importance Glucagon-like peptide 1 receptor agonists (GLP-1RAs) may have nephroprotective properties beyond those related to weight loss and glycemic control. Objective To investigate the association of genetically proxied GLP-1RAs with kidney disease progression. Design, Setting, Participants This genetic study assembled a national retrospective cohort veterans aged 18 years or older from US Department Veterans Affairs Million Veteran Program between January 10, 2011, December 31, 2021....
Background: Ensuring enhanced delivery of care to women Veterans is a top Affairs (VA) priority; however, are historically underrepresented in research that informs evidence-based health care. A primary barrier women's participation the inability engage with person due number documented challenges. The VA Million Veteran Program (MVP) committed increasing access for participate research, thereby better understanding conditions specific this population and how disease manifests differently...
Abstract Background Genome-wide Association Studies (GWAS) aims to uncover the link between genomic variation and phenotype. They have been actively applied in cancer biology investigate associations variations phenotypes, such as susceptibility certain types of predisposed responsiveness specific treatments. Since GWAS primarily focuses on finding individual there are limitations understanding mechanisms by which phenotypes cooperatively affected more than one variation. Results This paper...