A5051283952- Behavioral Health and Interventions
- Substance Abuse Treatment and Outcomes
- Mental Health Research Topics
- Decision-Making and Behavioral Economics
- Genetic Associations and Epidemiology
- Functional Brain Connectivity Studies
- Smoking Behavior and Cessation
- Eating Disorders and Behaviors
- Advanced Neuroimaging Techniques and Applications
- Gambling Behavior and Treatments
- Neurotransmitter Receptor Influence on Behavior
- Alcohol Consumption and Health Effects
- Neural and Behavioral Psychology Studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Attention Deficit Hyperactivity Disorder
- Nicotinic Acetylcholine Receptors Study
- Cannabis and Cannabinoid Research
- Personality Disorders and Psychopathology
- Genetics and Neurodevelopmental Disorders
- Obesity, Physical Activity, Diet
- Child and Adolescent Psychosocial and Emotional Development
- Schizophrenia research and treatment
- Bipolar Disorder and Treatment
- Opioid Use Disorder Treatment
- Healthcare Policy and Management
Uniformed Services University of the Health Sciences
2017-2025
Walter Reed National Military Medical Center
2025
University of Alabama at Birmingham
2025
Emory University
2025
Neurobehavioral Systems
2025
VA Palo Alto Health Care System
2025
Stanford University
2025
University of Minnesota
2025
Yale University
2025
University of Georgia
2013-2023
Impulsive personality traits are complex heritable that governed by frontal-subcortical circuits and associated with numerous neuropsychiatric disorders, particularly drug abuse attention-deficit/hyperactivity disorder (ADHD). In collaboration the genetics company 23andMe, we performed 10 genome-wide association studies on measures of impulsive [the short version UPPS-P Behavior Scale, Barratt Impulsiveness Scale (BIS-11)] experimentation (the number classes an individual had tried in their...
The gender gap in physician pay is often attributed part to women working fewer hours than men, but evidence date limited by self-report and a lack of detail regarding clinical revenue differences practice style.
<h3>Importance</h3> This study was designed to determine whether a preventive intervention focused on enhancing supportive parenting could ameliorate the association between exposure poverty and brain development in low socioeconomic status African American individuals from rural South. <h3>Objective</h3> To participation an efficacious prevention program enhance for children will living reduced hippocampal amygdalar volumes adulthood. <h3>Design, Setting, Participants</h3> In southeastern...
The 27-item Monetary Choice Questionnaire (MCQ; Kirby, Petry, & Bickel, 1999) and 30-item Probability Discounting (PDQ; Madden, Johnson, 2009) are widely used, validated measures of preferences for immediate versus delayed rewards guaranteed risky rewards, respectively. MCQ discounting by asking individuals to choose between available immediately larger after a delay. PDQ probability chance at winning rewards. Numerous studies have implicated these in addiction other health behaviors. Unlike...
Genetic factors contribute to the risk for developing alcohol use disorder (AUD). In collaboration with genetics company 23andMe, Inc., we performed a genome-wide association study of identification test (AUDIT), an instrument designed screen misuse over past year. Our final sample consisted 20 328 research participants European ancestry (55.3% females; mean age = 53.8, SD 16.1) who reported ever using alcohol. results showed that 'chip-heritability' AUDIT score, when treated as continuous...
Importance Recently, the US Food and Drug Administration gave premarketing approval to an algorithm based on its purported ability identify individuals at genetic risk for opioid use disorder (OUD). However, clinical utility of candidate variants included in has not been independently demonstrated. Objective To assess 15 from intended predict OUD risk. Design, Setting, Participants This case-control study examined association with using electronic health record data December 20, 1992,...
Abstract Accurate real-time monitoring systems of influenza outbreaks help public health officials make informed decisions that may save lives. We show information extracted from cloud-based electronic records databases, in combination with machine learning techniques and historical epidemiological information, have the potential to accurately reliably provide near regional estimates flu United States.
An Alcohol Purchase Task (APT) is a novel behavioral economic measure for characterizing the incentive value of alcohol to an individual (i.e., demand). Individual differences in demand have been associated with number alcohol-related outcomes and current investigation sought extend these previous findings ways. The goals study were: (a) examine relationship between misuse large sample community adults; (b) sex demand; and, (c) impulsive personality traits, both general as moderating...
Cigarette smoking is associated with increased risk for myriad health consequences including cognitive decline and dementia, but research on the link between brain structure nascent. In current study, we assessed relationship of cigarette gray matter (GM) white (WM) in UK Biobank, controlling numerous confounding demographic variables. We used negative-binomial regression to model association (having ever smoked regularly, cigarettes per day, duration smoked) GM WM (GM N = 19,615; 17,760),...
Abstract Background Previous research has implicated demographic, psychological, behavioral, and cognitive variables in the onset maintenance of pediatric overweight/obesity. No adequately-powered study simultaneously modeled these to assess their relative associations with body mass index (BMI; kg/m 2 ) a nationally representative sample youth. Methods Multiple machine learning regression approaches were employed estimate importance 43 previously associated BMI youth elucidate both fixed...
The aim of the present study was 2-fold: (1) to utilize improved amygdala segmentation and exploratory factor analysis characterize latent volumetric structure among nuclei (2) assess effect adverse childhood experiences (ACEs) on amygdalar morphometry current psychiatric symptoms. To investigate these aims, structural (T1) MRI self-report data were obtained from 119 emerging adults. Regression showed that higher ACE scores related reduced volume right, but not left, segments. Further,...
Despite growing preclinical evidence that glucagon-like peptide-1 receptor agonists (GLP-1RAs) could be repurposed to treat alcohol use disorder (AUD), clinical is scarce. Additionally, the potential impact of dipeptidyl peptidase-4 inhibitors (DPP-4Is) on intake largely unknown. We conducted a large cohort study using 2008-2023 electronic health records data from U.S. Department Veterans Affairs. Changes in Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) scores were compared...
Although personality traits have been linked to internalizing and externalizing psychopathology, the extent which these psychopathological phenotypes share a common neuroanatomical structure is unclear. To address this gap, we used structural neuroimaging self-report data from 1101 participants in Human Connectome Project generate profiles (NAPs) of FFM psychopathology indices composed thickness, surface area, gray matter volume each region Desikan atlas, then profile matching approach...
This study is a replication of an existing large (N = 507) on the surface-based morphometric correlates five-factor model (FFM) personality traits. The same methods were used as original in another sample drawn from population 597) with results then being aggregated both samples 1104), providing largest investigation into neuroanatomical FFM traits to date. Clusters association between brain morphometry and each trait are reported. For neuroticism, agreeableness, openness conscientiousness...
While most primary care physicians treated at least one Medicaid patient in 2013, represented a small share of their payer mix. Following eligibility expansion 2014, maintained or slightly increased participation, with greater increases observed states that expanded eligibility. Nevertheless, patients remained concentrated among relatively few after expansion.
While the neuroanatomical correlates of impulsivity in youths have been examined, there is little research on whether those are consistent across childhood/adolescence. The current study uses data from age 11/12 (N = 7,083) visit Adolescent Brain Cognitive Development Study to investigate replicability previous work (Owens et al., 2020) impulsive personality traits identified at 9/10. Neuroanatomy was measured using structural and diffusion magnetic resonance imaging, UPPS-P Impulsive...